Results 1 to 10 of about 810,225 (279)

Placental studies elucidate discrepancies between NIPT showing a structural chromosome aberration and a differently abnormal fetal karyotype. [PDF]

Prenat Diagn, 2019
Placental cytogenetic studies may reveal the origin of discordant noninvasive prenatal testing (NIPT). We performed placental studies to elucidate discordances between NIPT showing a structural chromosome aberration and the fetus having a different ...
Van Opstal D, van Veen S, Joosten M, Diderich KEM, Govaerts LCP, Polak J, van Koetsveld N, Boter M, Go ATJI, Papatsonis DNM, Prinsen K, Hoefsloot LH, Srebniak MI.   +12 more
europepmc   +2 more sources

Dose-Response Curve of Chromosome Aberrations in Human Lymphocytes Induced by Gamma-Rays [PDF]

Atom Indonesia, 2013
Chromosome aberration is a biomarker to predict the level of cell damage caused by exposure to ionizing radiation on human body. Dicentric chromosome is a specific chromosome aberration caused by ionizing radiation and is used as a gold standard ...
Y. Lusiyanti, Z. Alatas, M. Lubis, V.A. Suvifan, D. Ramadhani, S. Purnami   +5 more
doaj   +5 more sources

Renormalization of radiobiological response functions by energy loss fluctuations and complexities in chromosome aberration induction: deactivation theory for proton therapy from cells to tumor control. [PDF]

Eur Phys J D At Mol Opt Phys, 2019
We employ a multi-scale mechanistic approach to investigate radiation induced cell toxicities and deactivation mechanisms as a function of linear energy transfer in hadron therapy.
Abolfath R, Helo Y, Bronk L, Carabe A, Grosshans D, Mohan R.   +5 more
europepmc   +2 more sources

Titanium dioxide nanoparticles: an in vitro study of DNA binding, chromosome aberration assay, and comet assay. [PDF]

Cytotechnology, 2017
Patel S, Patel P, Bakshi SR.
europepmc   +2 more sources

Genotoxic and antigenotoxic effects of Fucus vesiculosus extract on cultured human lymphocytes using the chromosome aberration and Comet assays

Genetics and Molecular Biology, 2007
The brown seaweed Fucus vesiculosus (Fucales, Fucaceae) was screened for its protective activity using doxorubicin-induced DNA damage in human lymphocytes.
Cleide Leite-Silva, Cássia Lima Silva Gusmão, Catarina Satie Takahashi   +2 more
doaj   +2 more sources

Analysis of the Chromosomal Aberrations in Hepatitis B Virus (HBV), Hepatitis C Virus (HCV), and Hepatocellular Carcinoma Patients (HCC) in Mosul City, Iraq

NTU Journal of Pure Sciences, 2022
. Hepatocellular carcinoma (HCC) (also known as liver cancer) is one of the most frequent cancers in humans. HCC is linked to chronic hepatitis B and C virus infection, cirrhosis, and excessive alcohol consumption.
Alaa Younis Mahdy Alhamadany, Wajdi Sabeeh Sadek   +1 more
doaj   +1 more source

Risk factor analysis for adverse prognosis of the fetal ventricular septal defect (VSD)

BMC Pregnancy and Childbirth, 2023
Background Ventricular septal defect (VSD) is the most common subtype of congenital heart disease. In the present study, we aimed to determine whether chromosome aberration was associated with the occurrence of VSD and evaluate the association of VSD ...
Wang Shan, Xia Yuanqing, Zhu Jing, Wu Xi, Guo Huifeng, Wu Yi   +5 more
doaj   +1 more source

Alpha-particle-induced complex chromosome exchanges transmitted through extra-thymic lymphopoiesis in vitro show evidence of emerging genomic instability [PDF]

, 2015
Human exposure to high-linear energy transfer α-particles includes environmental (e.g. radon gas and its decay progeny), medical (e.g. radiopharmaceuticals) and occupational (nuclear industry) sources.
A Duran, AA Edwards, BD Loucas, CA Whitehouse, CL Limoli, CS Griffin, D Becker, DL Henshaw, DT Goodhead, DT Goodhead, Dudley T. Goodhead, EG Wright, Ester Hammond, FE Alexander, FK Kong, G Kendall, GB Curwen, GB Curwen, GE Watson, GE Watson, H Jadvar, H Nikjoo, HA Foster, HG Paretzke, HT Petrie, I, J Sevc, JD Harrison, JE Moquet, JM Samet, JR Savage, KA George, KL Johnson, KM Greulich, L Al-Harthi, LG Littlefield, M Ahmad, M Durante, M Kadhim, M Themis, MA Kadhim, MA Kadhim, MA Kadhim, MA Kadhim, MA Kadhim, MD Hazenberg, MJ Ramsey, MN Cornforth, MR Speicher, Natalia Sumption, NV Sotnik, RF Hobbs, Rhona M. Anderson, RM Anderson, RM Anderson, RM Anderson, RM Anderson, RM Anderson, S Bonassi, S Chakraborty, S Darby, S Darby, T Lapidot, W Friedland, W Vuong, WF Morgan, Y Kodama   +66 more
core   +11 more sources

Modeling of ionizing radiation-induced chromosome aberration and tumor prevalence based on two classes of DNA double-strand breaks clustering in chromatin domains

Ecotoxicology and Environmental Safety, 2023
There has been some controversy over the use of radiobiological models when modeling the dose-response curves of ionizing radiation (IR)-induced chromosome aberration and tumor prevalence, as those curves usually show obvious non-targeted effects (NTEs ...
Lei Zhao, Aiping Tang, Fei Long, Dong Mi, Yeqing Sun   +4 more
doaj   +1 more source

Aberrations of chromosome 8 in myelodysplastic syndromes: Clinical and biological significance [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2006
Introduction: Rearrangements of any single chromosome in human karyotype have been reported in patients with pMDS. Objective: To examine the role of aberrations of chromosome 8 in pathogenesis, clinical presentation and progression of myelodysplastic ...
Marisavljević Dragomir, Pantić-Ludoški Milena, Novak Angelina, Đorđević Vesna   +3 more
doaj   +1 more source