Results 31 to 40 of about 21,431 (261)

Cytogenetic analysis of 1284 cases of Down syndrome [PDF]

Journal of Kerman University of Medical Sciences, 1997
Among 17786 karyotyres performed in our center,during 18 years (1357-1375),1300(7.3%) cases of chromosome 21 aberration,including 1284(98.77%) of Down syndrome have been detected.1191 of cases (92.76%) born free trisomy 21:61 cases (4.75%) revealed ...
M.H Kariminejhad, R Kariminejhad, F Azimi, N Nabavi nia, K Alavi, M.T Takyar, Y Shafeghati   +6 more
doaj  

Cytogenetic Study among Chemical Bombardment Survivors in Shekh Wasan & Balisan Valley Kurdistan Region-Iraq [PDF]

Eurasian Journal of Science and Engineering, 2017
This study was performed randomly on 40 individuals selected within a specific period, between January 2014 to October 2014 in order to a certain whether or not a sample of chemical weapons used on Shekh Wasan & Balisan valley in 16 April 1987, have ...
Hazha Jamal Hidayet, Sheeman Hameed Mohammed   +1 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Dose-Response Curve of Chromosome Aberrations in Human Lymphocytes Induced by Gamma-Rays

Atom Indonesia, 2013
Chromosome aberration is a biomarker to predict the level of cell damage caused by exposure to ionizing radiation on human body. Dicentric chromosome is a specific chromosome aberration caused by ionizing radiation and is used as a gold standard ...
Y. Lusiyanti, Z. Alatas, M. Lubis, V.A. Suvifan, D. Ramadhani, S. Purnami   +5 more
doaj  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Study on the cytotoxicity and chromosome aberration following implantation of sea coral in rabbits

Dental Journal, 2006
Coral has been used as a bone substitute in many experimental studies. It has been proven to be biocompatible, biodegradable and easy to handle: and it has not been found to cause any inflammatory responses.
Kannan TP, Freeda Woon Faiza Woon Tai Keat, Widowati Witjaksono, Abdul Rani Samsudin   +3 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Induction of Chromosomes Aberration and Micronucleus by Glyphosate Herbicide in Bone Marrow Cell of Male Mice Mus Musculus

مجلة علوم ذي قار, 2019
The present study was designed to investigate the ability of the herbicide Glyphosate to induce cytogenetic effects in the laboratory mice Mus musculus, using chromosomal aberration and micronucleus parameters.
Faizah W. Ahmed
doaj   +4 more sources

Study of Indicators for Early and Rapid Diagnosis of Radiation Injury Is the Most Important in Patients With Cancer During Radiotherapy

Dose-Response, 2020
Objective: To establish a complete technical solution for the radiation biological dose estimation, to enable prediction of individuals’ response to radiotherapy (RT), and to control treatment dose for reduced irradiation injury and promote repair; and ...
Gang Liu, Li-Mei Niu, Li-Qin Wang, Ye Li, Xiao-Qin Wu, Yin-Yin Liu, Rong Zhang   +6 more
doaj   +1 more source

In vitro Evaluation of Antigenotoxic Effects of Phloridzin

Cumhuriyet Science Journal, 2022
Phytochemicals have a vast number of properties contributing to human health by acting on numerous different mechanisms. Phloridzin, a phytochemical mainly found in Malus species, possesses diverse biological activities including anti-diabetic and ...
Mehmet Sarimahmut, Sindi Vekshari, Serap Celikler, Merve Demirbag Karaali   +3 more
doaj   +1 more source