This study was carried out to investigate the cytogenetic effects of crude aqueous extract of Lycium barbarum on the roots tip of Allium cepa Using three concentration 125, 25, 50 mg/ ml for 2, 4, 6 hours treatment periods.This study were included some
Baghdad Science Journal
doaj +1 more source
No increase in radiation-induced chromosome aberration complexity detected by m-FISH after culture in the presence of 5’-bromodeoxyuridine [PDF]
The thymidine analogue, 5’-bromodeoxyuridine (BrdU), is a known mutagen that is routinely introduced into culture media for subsequent Harlequin stain analysis and determination of cell cycle status.
Anderson +38 more
core +1 more source
Comparison of Radiosensitivity of Human Chromosomes 1, 2 and 4 from One Healthy Donor
In general, it was assumed that the chromosome aberration induced by ionizing radiation is proportional to the chromosome size. From this viewpoint, the higher chromosome size, the more resistant to radiation.
D. Ramadhani, S. Purnami, M. Yoshida
doaj +1 more source
Genotoxicity of Di (2-ethyl hexyl) phthalate
ObjectiveTo assess the genotoxicity of Di(2-ethylhexyl) phthalate (DEHP).MethodsA series of guideline-compliant assays were performed to evaluate mutagenicity, chromosomal or DNA damage of DEHP, including Ames test, in vitro mammalian chromosome ...
LI Juntao +9 more
doaj +1 more source
Rapid metaphase and interphase detection of radiation-induced chromosome aberrations in human lymphocytes by chromosomal suppression in situ hybridization [PDF]
Chromosomal in situ suppression (CISS)-hybridization of biotinylated phage DNA-library inserts from sorted human chromosomes was used to decorate chromosomes 1 and 7 specifically from pter to qter and to detect structural aberrations of these chromosomes
Cremer, Christoph +4 more
core +1 more source
Acute toxicity and genotoxicity studies on new melatonergic antidepressant GW117
GW117, a novel derivate compound of agomelatine that acts as both a 5-HT2C receptor antagonist and a MT1/MT2 receptor agonist, likely underlines the potent antidepressant action with less hepatotoxicity than agomelatine.
Mei Gao +8 more
doaj +1 more source
The micronucleus assay as a biological dosimeter of in vivo ionising radiation exposure [PDF]
Biological dosimetry, based on the analysis of micronuclei (MN) in the cytokinesis-block micronucleus (CBMN) assay can be used as an alternative method for scoring dicentric chromosomes in the field of radiation protection.
Fenech, Michel +2 more
core +2 more sources
Placing women in Cytogenetics: Lore Zech and the chromosome banding technique
Background Scholars agree that Torbjörn Caspersson’s lab at the Institute of Medical Cell Research and Genetics at the Karolinska Institute, Sweden, played a key role in the first description of the so-called Q-banding technique.
Felicitas Söhner, Nils Hansson
doaj +1 more source
Efficacy and functionality of sugarcane original vinegar on mice
IntroductionDue to their bioactive compounds and beneficial health effects, functional foods and plant-based natural medicines are widely consumed. Due to its bioactivities, vinegar is one of them that helps humans.
Feng-Jin Zheng +11 more
doaj +1 more source
Chromosome breakage after G2 checkpoint release [PDF]
DNA double-strand break (DSB) repair and checkpoint control represent distinct mechanisms to reduce chromosomal instability. Ataxia telangiectasia (A-T) cells have checkpoint arrest and DSB repair defects. We examine the efficiency and interplay of ATM's
Beucher, Andrea +8 more
core +4 more sources

