PLoS ONEMulti-layer Complex networks are commonly used for modeling and analysing biological entities. This paper presents the advantage of using COMBO (Combining Multi Bio Omics) to suggest a new role of the chromosomal aberration as a cancer driver factor ...
Ilaria Cosentini +6 more
doaj +1 more source
9q21.13q21.31 deletion in a patient with intellectual disability severe speech delay and and dysmorphic features a newly recognized microdeletion syndrome [PDF]
, 2019 The increased use of chromosomal microarray analysis has led to the identification of new microdeletion/microduplication syndromes, enabling better genotype-phenotype correlations.
Correia, Hildeberto +6 more
core +1 more source
The effect of paclitaxel alone and in combination with cycloheximide on the frequency of premature centromere division in vitro [PDF]
Archives of Biological Sciences, 2010 Premature centromere division (PCD) can be viewed as a manifestation of chromosome instability. In order to evaluate the ability of Paclitaxel (Ptx) and Cycloheximide (Cy) to induce PCD we used a cytokinesis block micronucleus assay (CBMN), fluorescent ...
Bajić V. +5 more
doaj +1 more source
, 2004 Genotoxicity studies on toxic metals and their organic compounds are very important, especially so in the investigation of the effects of these compounds on the aquatic environments where they tend to accumulate.
M. Ferraro +4 more
semanticscholar +1 more source
Time Course of PR of UV-Induced Chromosomal Aberrations and Lethal Damage in G1 Xenopus Cells [PDF]
, 1977 Synchronous cultures of early G1 cells were exposed to UV and their ability to photoreactivate lethal and aberrational damage was determined as a function of time following UV exposure.
Griggs, H. Gaston, Payne, Jan
core +2 more sources
Modelling radiation-induced cell cycle delays
, 2009 Ionizing radiation is known to delay the cell cycle progression. In particular after particle exposure significant delays have been observed and it has been shown that the extent of delay affects the expression of damage such as chromosome aberrations ...
AD Virgilio +34 more
core +1 more source
The protective effect of vitamin E against genotoxicity of lead acetate intraperitoneal administration in male rat [PDF]
Archives of Biological Sciences, 2013 Lead is an industrial pollutant that may exert specific toxic effects on male mammals. The aim of this study was to investigate further the protective effects of vitamin E on lead acetate (Pb)-induced reproductive toxicities and genotoxic ...
Hamadouche Nadia Ait +4 more
doaj +1 more source
, 2022 Eunnara Cho +12 more
openalex +1 more source
Hyperforin Exhibits Antigenotoxic Activity on Human and Bacterial Cells
Molecules, 2017 Hyperforin (HF), a substance that accumulates in the leaves and flowers of Hypericum perforatum L. (St. John’s wort), consists of a phloroglucinol skeleton with lipophilic isoprene chains. HF exhibits several medicinal properties and is mainly used as an
Petronela Imreova +10 more
doaj +1 more source
Life, 2020 During space travel, humans are continuously exposed to two major environmental stresses, microgravity (μG) and space radiation. One of the fundamental questions is whether the two stressors are interactive.
Sakuya Yamanouchi +6 more
doaj +1 more source