Combination of QF‐PCR and aCGH is an efficient diagnostic strategy for the detection of chromosome aberrations in recurrent miscarriage [PDF]
Molecular Genetics & Genomic Medicine, 2019 Background Our aim was to conduct a comprehensive genetic evaluation using the combination of QF‐PCR (quantitative fluorescence polymerase chain reaction) and aCGH (array comparative genomic hybridization) for the detection of the frequency and type of ...
Luca Lovrečić +4 more
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Impact of Radiation Quality on Microdosimetry and Chromosome Aberrations for High-Energy (>250 MeV/n) Ions [PDF]
Life, 2022 Studying energy deposition by space radiation at the cellular scale provides insights on health risks to astronauts. Using the Monte Carlo track structure code RITRACKS, and the chromosome aberrations code RITCARD, we performed a modeling study of single-
Floriane Poignant +3 more
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Chromosome aberrations in pressure-induced triploid Atlantic salmon [PDF]
BMC Genetics, 2020 Background Triploid organisms have three sets of chromosomes. In Atlantic salmon, hydrostatic pressure treatment of newly fertilized eggs has been extensively used to produce triploids which are functionally sterile due to their unpaired chromosomes ...
K. A. Glover +8 more
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Chromosome-specific aberrations, rather than general aneuploidy, may drive mouse embryonic stem cell-derived teratoma metastasis [PDF]
Stem Cell Research & TherapyIntroduction Pluripotent stem cells (PSC) are known to recurrently acquire genetic aberrations including chromosomal aneuploidy during long-term culture of which the consequences remain largely unknown.
Joaquin Montilla-Rojo +4 more
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Radiation and Chromosome Aberration
Japanese Journal of Health Physics, 1966 In a recent decade, human cytogenetics has been developed very rapidly with advancement of tissue culture technique. This review introduces the basic mechanism of chromosome aberrations in human somatic cells, especially, leucocytes and relationship between abnormalities and irradiation.
Koji OHKURA
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Chromosomal Aberrations in Cattle [PDF]
Genes, 2021 Chromosomal aberrations and their mechanisms have been studied for many years in livestock. In cattle, chromosomal abnormalities are often associated with serious reproduction-related problems, such as infertility of carriers and early mortality of embryos.
Beáta Holečková +7 more
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Sporadic chromosome translocation frequencies in lymphocyte cultures – a retrospective study in a cohort of patients from Bosnia and Herzegovina [PDF]
Medicinski Glasnik, 2022 Aim Chromosome translocations are considered as one of the most severe forms of genome defects. Because of the clinical significance of chromosome translocations and scarce data on the incidence of sporadic translocations in population of Bosnia and ...
Sanin Haverić +5 more
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Aberrations Involving Chromosome 1 as a Possible Predictor of Odds Ratio for Colon Cancer--Results from the Krakow Case-Control Study. [PDF]
PLoS ONE, 2016 There is still an open question how to predict colorectal cancer risk before any morphological changes appear in the colon.The purpose was to investigate aberrations in chromosomes 1, 2 and 4 in peripheral blood lymphocytes analyzed by fluorescence in ...
Aleksander Galas, Justyna Miszczyk
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Toxics, 2022 Ionizing radiation is a well-known carcinogen that causes genomic instability. However, the biological and carcinogenetic effects of occupational radiation exposure at low doses have not been extensively studied.
Yang Jee Kim +5 more
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Aberrations of chromosome 8 in myelodysplastic syndromes: Clinical and biological significance [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2006 Introduction: Rearrangements of any single chromosome in human karyotype have been reported in patients with pMDS. Objective: To examine the role of aberrations of chromosome 8 in pathogenesis, clinical presentation and progression of myelodysplastic ...
Marisavljević Dragomir +3 more
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