Why it is crucial to analyze non clonal chromosome aberrations or NCCAs? [PDF]
Current cytogenetics has largely focused its efforts on the identification of recurrent karyotypic alterations, also known as clonal chromosomal aberrations (CCAs).
Heng HH, Regan SM, Liu G, Ye CJ.
europepmc +2 more sources
Impact of Radiation Quality on Microdosimetry and Chromosome Aberrations for High-Energy (>250 MeV/n) Ions [PDF]
Studying energy deposition by space radiation at the cellular scale provides insights on health risks to astronauts. Using the Monte Carlo track structure code RITRACKS, and the chromosome aberrations code RITCARD, we performed a modeling study of single-
Floriane Poignant +3 more
doaj +2 more sources
Combination of QF‐PCR and aCGH is an efficient diagnostic strategy for the detection of chromosome aberrations in recurrent miscarriage [PDF]
Background Our aim was to conduct a comprehensive genetic evaluation using the combination of QF‐PCR (quantitative fluorescence polymerase chain reaction) and aCGH (array comparative genomic hybridization) for the detection of the frequency and type of ...
Luca Lovrečić +4 more
doaj +2 more sources
Chromosome aberrations in pressure-induced triploid Atlantic salmon [PDF]
Background Triploid organisms have three sets of chromosomes. In Atlantic salmon, hydrostatic pressure treatment of newly fertilized eggs has been extensively used to produce triploids which are functionally sterile due to their unpaired chromosomes ...
K. A. Glover +8 more
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Human cytomegalovirus UL76 induces chromosome aberrations
Background Human cytomegalovirus (HCMV) is known to induce chromosome aberrations in infected cells, which can lead to congenital abnormalities in infected fetuses. HCMV UL76 belongs to a conserved protein family from herpesviruses.
Wang Shang-Kwei +2 more
doaj +2 more sources
To assess the genotoxicity of 14 chemical agents used in dental practice, the ability of these agents to induce chromosome aberrations was examined using Syrian hamster embryo (SHE) cells.
Hirohito Hikiba +3 more
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Radiation and Chromosome Aberration
In a recent decade, human cytogenetics has been developed very rapidly with advancement of tissue culture technique. This review introduces the basic mechanism of chromosome aberrations in human somatic cells, especially, leucocytes and relationship between abnormalities and irradiation.
Koji OHKURA
openalex +3 more sources
Chromosome-specific aberrations, rather than general aneuploidy, may drive mouse embryonic stem cell-derived teratoma metastasis [PDF]
Introduction Pluripotent stem cells (PSC) are known to recurrently acquire genetic aberrations including chromosomal aneuploidy during long-term culture of which the consequences remain largely unknown.
Joaquin Montilla-Rojo +4 more
doaj +2 more sources
Chromosomal Aberrations in Cattle [PDF]
Chromosomal aberrations and their mechanisms have been studied for many years in livestock. In cattle, chromosomal abnormalities are often associated with serious reproduction-related problems, such as infertility of carriers and early mortality of embryos.
Beáta Holečková +7 more
openaire +3 more sources
Sporadic chromosome translocation frequencies in lymphocyte cultures – a retrospective study in a cohort of patients from Bosnia and Herzegovina [PDF]
Aim Chromosome translocations are considered as one of the most severe forms of genome defects. Because of the clinical significance of chromosome translocations and scarce data on the incidence of sporadic translocations in population of Bosnia and ...
Sanin Haverić +5 more
doaj +1 more source

