Combination of QF‐PCR and aCGH is an efficient diagnostic strategy for the detection of chromosome aberrations in recurrent miscarriage [PDF]
Molecular Genetics & Genomic Medicine, 2019 Background Our aim was to conduct a comprehensive genetic evaluation using the combination of QF‐PCR (quantitative fluorescence polymerase chain reaction) and aCGH (array comparative genomic hybridization) for the detection of the frequency and type of ...
Luca Lovrečić +4 more
doaj +2 more sources
Impact of Radiation Quality on Microdosimetry and Chromosome Aberrations for High-Energy (>250 MeV/n) Ions [PDF]
Life, 2022 Studying energy deposition by space radiation at the cellular scale provides insights on health risks to astronauts. Using the Monte Carlo track structure code RITRACKS, and the chromosome aberrations code RITCARD, we performed a modeling study of single-
Floriane Poignant +3 more
doaj +2 more sources
Chromosome aberrations in pressure-induced triploid Atlantic salmon [PDF]
BMC Genetics, 2020 Background Triploid organisms have three sets of chromosomes. In Atlantic salmon, hydrostatic pressure treatment of newly fertilized eggs has been extensively used to produce triploids which are functionally sterile due to their unpaired chromosomes ...
K. A. Glover +8 more
doaj +2 more sources
A polymer physics model of the interphase cell nucleus for radiobiological simulations [PDF]
Scientific ReportsAdvances in chromatin architectures achieved through super-resolution imaging and high-throughput chromosome conformation capture (Hi-C) techniques remain to be integrated into the modeling framework of radiobiology.
Man Zhao +4 more
doaj +2 more sources
Biological effects of conventional and ultra high dose rate radiation in human cells [PDF]
Scientific ReportsFLASH radiotherapy (FLASH-RT) that uses an ultra-high dose rate (UHDR) radiation is emerging as an effective cancer treatment modality but the biological effects of UHDR are not fully understood.
Terri L. Ryan +13 more
doaj +2 more sources
Sporadic chromosome translocation frequencies in lymphocyte cultures – a retrospective study in a cohort of patients from Bosnia and Herzegovina [PDF]
Medicinski Glasnik, 2022 Aim Chromosome translocations are considered as one of the most severe forms of genome defects. Because of the clinical significance of chromosome translocations and scarce data on the incidence of sporadic translocations in population of Bosnia and ...
Sanin Haverić +5 more
doaj +1 more source
Aberrations Involving Chromosome 1 as a Possible Predictor of Odds Ratio for Colon Cancer--Results from the Krakow Case-Control Study. [PDF]
PLoS ONE, 2016 There is still an open question how to predict colorectal cancer risk before any morphological changes appear in the colon.The purpose was to investigate aberrations in chromosomes 1, 2 and 4 in peripheral blood lymphocytes analyzed by fluorescence in ...
Aleksander Galas, Justyna Miszczyk
doaj +1 more source
Toxics, 2022 Ionizing radiation is a well-known carcinogen that causes genomic instability. However, the biological and carcinogenetic effects of occupational radiation exposure at low doses have not been extensively studied.
Yang Jee Kim +5 more
doaj +1 more source
Taiwanese Journal of Obstetrics & Gynecology, 2006 Objective: To retrospectively investigate the 10-year experience of prenatal diagnosis of fetal chromosome aberrations by second-trimester amniocentesis.
Jenn-Jhy Tseng +5 more
doaj +1 more source
Journal of Health Sciences, 2016 Introduction: Cigarette smoking is associated with severe health problems, especially cancers. In addition, cigarette smoking causes different genotoxic effects. Chromosome aberrations are one of well-known intermediate end points in carcinogenesis.
Anja Haverić +2 more
doaj +1 more source