Relative proximity of chromosome territories influences chromosome exchange partners in radiation-induced chromosome rearrangements in primary human bronchial epithelial cells [PDF]
, 2013 Copyright © 2013 The Authors. This article is made available through the Brunel Open Access Publishing Fund. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-No Derivative Works License, which ...
Anderson, RM +6 more
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Comparative analysis of the yields of dicentrics and chromosomal translocations [PDF]
arXiv, 2023 Purpose: Chromosomal dicentrics and translocations are commonly employed as biomarkers to estimate radiation doses. The main goal of this article is to perform a comparative analysis of yields of both types of aberrations. The objective is to determine if there are relevant distinctions between both yields, allowing for a comprehensive assessment of ...
arxiv
Modelling radiation-induced cell cycle delays [PDF]
Published online: Radiation and Environmental Biophysics, 2009.
The original publication is available at
http://www.springerlink.com/content/l33041651m10815w/, 2009 Ionizing radiation is known to delay the cell cycle progression. In particular after particle exposure significant delays have been observed and it has been shown that the extent of delay affects the expression of damage such as chromosome aberrations.
arxiv +1 more source
Chromosome breakpoint distribution of damage induced in peripheral blood lymphocytes by densely ionising radiation [PDF]
, 2006 Purpose: To assess the chromosomal breakpoint distribution in human peripheral blood lymphocytes (PBL) after exposure to a low dose of high linear energy transfer (LET) α-particles using the technique of multiplex fluorescence in situ hybridisation (m ...
Anderson, RM +3 more
core +1 more source
Biomarkers of leukemia risk: benzene as a model. [PDF]
, 1998 Although relatively rare, leukemias place a considerable financial burden on society and cause psychologic trauma to many families. Leukemia is the most common cancer in children.
Smith, MT, Zhang, L
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Study of Ultraviolet-Induces Chromatid and Chromosome Aberrations as a Function of Dose in G1 Phase Vertebrate Tissue Cultures [PDF]
, 1976 G1 phase A8 Xenopus laevis (toad) and V79B Cricetulus griseus (hamster) tissue cultures were used to observe the frequency of ultraviolet-induced chromosomal aberrations as a function of dose.
Griggs, H. Gaston, Orr, Troy V.
core +2 more sources
Detection of chromosome aberrations in metaphase and interphase tumor cells by in situ hybridization using chromosome-specific library probes [PDF]
, 1988 Chromosome aberrations in two glioma cell lines were analyzed using biotinylated DNA library probes that specifically decorate chromosomes 1, 4, 7, 18 and 22 from pter to qter.
A Al-Saadi +38 more
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Hematopoietic cancers and Nup98 fusions: determining common mechanisms of malignancy [PDF]
, 2012 Chromosomal aberrations are very frequent in leukemias and several recurring mutations capable of malignant transformation have been described. These mutations usually occur in hematopoietic stem cells (HSC), transforming them into leukemia stem cells.
arxiv +1 more source
Effect of linear energy transfer (LET) on complexity of alpha-particle-induced chromosome aberrations in human CD34+ cells. [PDF]
, 2007 The aim of this study was to assess the relative influence of linear energy transfer (LET) of α-particles on chromosome aberration complexity in the absence of significant other track structure differences.
Anderson, RM +5 more
core
Development of a Biological Dosimeter for Translocation Scoring Based on Two-Color Fluorescence in Situ Hybridization of Chromosome Subsets [PDF]
, 1992 Recently fluorescence in situ hybridization protocols have been developed which allow the paining of individual chromosomes using DNA-libraries from sorted human chromosomes.
Cremer, Thomas, Popp, Susanne
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