Human cytomegalovirus UL76 induces chromosome aberrations
Journal of Biomedical Science, 2009 Background Human cytomegalovirus (HCMV) is known to induce chromosome aberrations in infected cells, which can lead to congenital abnormalities in infected fetuses. HCMV UL76 belongs to a conserved protein family from herpesviruses.
Wang Shang-Kwei +2 more
doaj +2 more sources
Why it is crucial to analyze non clonal chromosome aberrations or NCCAs? [PDF]
Mol Cytogenet, 2016 Current cytogenetics has largely focused its efforts on the identification of recurrent karyotypic alterations, also known as clonal chromosomal aberrations (CCAs).
Heng HH, Regan SM, Liu G, Ye CJ.
europepmc +2 more sources
Whole chromosome loss and genomic instability in mouse embryos after CRISPR-Cas9 genome editing
Nature Communications, 2021 Karyotype alterations have emerged as on-target complications from CRISPR-Cas9 genome editing. However, the events that lead to these karyotypic changes in embryos after Cas9-treatment remain unknown. Here, using imaging and single-cell genome sequencing
Stamatis Papathanasiou +6 more
semanticscholar +1 more source
RITCARD: Radiation-Induced Tracks, Chromosome Aberrations, Repair and Damage.
Radiation Research, 2019 Chromosome aberrations (CA) are one of the effects of radiation exposure and can have implications for human health in the space environment, since they are related to cancer risk.
I. Plante +4 more
semanticscholar +1 more source
Aberrations of chromosome 8 in myelodysplastic syndromes: Clinical and biological significance [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2006 Introduction: Rearrangements of any single chromosome in human karyotype have been reported in patients with pMDS. Objective: To examine the role of aberrations of chromosome 8 in pathogenesis, clinical presentation and progression of myelodysplastic ...
Marisavljević Dragomir +3 more
doaj +1 more source
Biomarkers of leukemia risk: benzene as a model. [PDF]
, 1998 Although relatively rare, leukemias place a considerable financial burden on society and cause psychologic trauma to many families. Leukemia is the most common cancer in children.
Smith, MT, Zhang, L
core +3 more sources
Journal of Health Sciences, 2016 Introduction: Cigarette smoking is associated with severe health problems, especially cancers. In addition, cigarette smoking causes different genotoxic effects. Chromosome aberrations are one of well-known intermediate end points in carcinogenesis.
Anja Haverić +2 more
doaj +1 more source
Chromosome aberrations and micronuclei in bone marrow cells and peripheral blood lymphocytes in humans exposed to ethylene oxide [PDF]
Hereditas, 2008 Twenty-eight individuals occupationally exposed to ethylene oxide have been compared with 20 controls regarding cytogenetic effects in peripheral blood lymphocytes and in bone marrow cells. The exposure levels of ethylene oxide were estimated and none of
Benkt Högstedt +6 more
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Biomolecules & Biomedicine, 2014 Endogenious opiod met-enkephalin throughout previous research manifested cytoprotective and anti-inflammatory effects. Previous research suggests that met-enkephalin has cytogenetic effects.
Maida Rakanović-Todić +3 more
doaj +1 more source
Alpha-particle-induced complex chromosome exchanges transmitted through extra-thymic lymphopoiesis in vitro show evidence of emerging genomic instability [PDF]
, 2015 Human exposure to high-linear energy transfer α-particles includes environmental (e.g. radon gas and its decay progeny), medical (e.g. radiopharmaceuticals) and occupational (nuclear industry) sources.
A Duran +66 more
core +6 more sources