Results 31 to 40 of about 119,997 (335)

Induction of chromosome damage by ultraviolet light and caffeine: Correlation of cytogenetic evaluation and flow karyotype [PDF]

, 1982
Asynchrononously growing cells of a M3-1 Chinese hamster line were ultraviolet (UV) irradiated ( = 254 nm) with UV fluences up to 7.5 J/m2. After irradiation, cells were incubated with or without 2 mM caffeine for 20 hr, then mitotic cells were selected ...
Carrano, Carrano, Carrano, Chu, Cremer, Cremer, Cremer, Cremer, Gray, Gray, Gray, Horan, Kato, Kihlman, Langlois, Lovelace, Moore, Nilsson, Otto, Roberts, Yu   +20 more
core   +1 more source

Dose assessment by quantification of chromosome aberrations and micronuclei in peripheral blood lymphocytes from patients exposed to gamma radiation [PDF]

Genetics and Molecular Biology, 2005
Scoring of unstable chromosome aberrations (dicentrics, rings and fragments) and micronuclei in circulating lymphocytes are the most extensively studied biological means for estimating individual exposure to ionizing radiation (IR), which can be used as ...
Isvânia Silva-Barbosa, Símey Pereira-Magnata, Ademir Amaral, Graça Sotero, Homero Cavalcanti Melo   +4 more
doaj   +1 more source

Rapid generation of chromosome-specific alphoid DNA probes using the polymerase chain reaction [PDF]

, 1992
Non-isotopic in situ hybridization of chromosome-specific alphoid DNA probes has become a potent tool in the study of numerical aberrations of specific human chromosomes at all stages of the cell cycle. In this paper, we describe approaches for the rapid
A Gnirke, AHN Hopman, AR Mitchell, C Huxley, C Lengauer, Christoph Lengauer, D Pinkel, ED Green, EW Jabs, HF Willard, HF Willard, HF Willard, HM Rosenberg, Ian Dunham, J Anastasi, J Meyne, JE Koch, JS Waye, JS Waye, JS Waye, L Manuelidis, L Manuelidis, M Klever, P Emmerich, PJ Poddighe, PR Langer, S Popp, T Cremer, T Cremer, T Cremer, T Imai, T Maniatis, Terry Featherstone, Thomas Cremer   +33 more
core   +1 more source

A Systematic Review of Reproductive Counseling in Cases of Parental Constitutional Reciprocal Translocation (9;22) Mimicking BCR-ABL1

Frontiers in Genetics, 2022
We aim to determine the spectrum of cytogenetic abnormalities and outcomes in unbalanced offspring of asymptomatic constitutional balanced t(9;22) carriers through a systematic literature review. We also include a case of a constitutional balanced t(9;22)
Zimeng Gao, Stephanie M. Rice, Sascha Wodoslawsky, Sara C. Long, Zi-Xuan Wang, Mehnoosh Torkzaban, Ana Milena Angarita Africano, Jinglan Liu, Huda B. Al-Kouatly   +8 more
doaj   +1 more source

Chromosomal damage among medical staff occupationally exposed to volatile anesthetics, antineoplastic drugs, and formaldehyde

Scandinavian Journal of Work, Environment & Health, 2013
OBJECTIVES: Structural chromosomal aberrations in blood lymphocytes represent a biomarker for cellular damage caused by genotoxic carcinogens and are an indicator of increased cancer risk.
Ludovit Musak, Zdenek Smerhovsky, Erika Halasova, Oto Osina, Lucia Letkova, Ludmila Vodickova, Veronika Polakova, Janka Buchancova, Kari Hemminki, Pavel Vodicka   +9 more
doaj   +1 more source

Genomic alterations in primary gastric adenocarcinomas correlate with clinicopathological characteristics and survival. [PDF]

, 2004
Background & aimsPathogenesis of gastric cancer is driven by an accumulation of genetic changes that to a large extent occur at the chromosomal level. In order to investigate the patterns of chromosomal aberrations in gastric carcinomas, we performed
Albertson, Donna, Kuipers, Ernst J, Meijer, Gerrit A, Meuwissen, Stefan GM, Pinkel, Daniel, Postma, Cindy, Snijders, Antoine M, Weiss, Marjan M   +7 more
core   +3 more sources

Human cytomegalovirus UL76 induces chromosome aberrations

Journal of Biomedical Science, 2009
Background Human cytomegalovirus (HCMV) is known to induce chromosome aberrations in infected cells, which can lead to congenital abnormalities in infected fetuses. HCMV UL76 belongs to a conserved protein family from herpesviruses.
Wang Shang-Kwei, Duh Chang-Yih, Siew Voon-Kwan   +2 more
doaj   +1 more source

Chromosome Aberrations of East Asian Bullfrog (Hoplobatrachus rugulosus) around a Gold Mine Area with Arsenic Contamination [PDF]

EnvironmentAsia, 2016
The objectives of this study are to investigate the chromosome aberrations of the East Asian Bullfrog (Hoplobatrachus rugulosus) in the gold mine area compared to an unaffected area. Three H.
Atidtaya Suttichaiya , Arthone Khammanichanh , Isara Patawang , Manop Sriuttha , Alongklod Tanamtong , Lamyai Neeratanaphan   +5 more
doaj   +1 more source

Chromosome breakage after G2 checkpoint release [PDF]

, 2006
DNA double-strand break (DSB) repair and checkpoint control represent distinct mechanisms to reduce chromosomal instability. Ataxia telangiectasia (A-T) cells have checkpoint arrest and DSB repair defects. We examine the efficiency and interplay of ATM's
Beucher, Andrea, Birraux, Julie, Deckbar, Dorothee, Jeggo, Penny, Krempler, Andrea, Löbrich, Markus, Stiff, Tom, Tchouandong, Leopoldine, Walker, Sarah   +8 more
core   +4 more sources

Conventional and Molecular Cytogenetic Analyses in Turkish Patients with Multiple Myeloma

Turkish Journal of Hematology, 2012
OBJECTIVE: Multiple myeloma (MM) is characterized by the accumulation and proliferation of malignant plasma cells, secreting monoclonal immunoglobulins and genetic abnormalities in MM have implications for disease progression and survival. In the present
Beyhan Durak Aras, Olga Meltem Akay, Gülçin Sungar, Güney Bademci, Vahap Aslan, Jülide Caferler, Muhsin Özdemir, Oğuz Çilingir, Sevilhan Artan, Zafer Gülbaş   +9 more
doaj   +1 more source