Results 151 to 160 of about 24,510 (263)

Single Nucleotide Polymorphism Microarray Analysis Unveils Copy-Number Abnormalities and Genetic Heterogeneity in Malaysian Childhood B-Cell Precursor Acute Lymphoblastic Leukemia. [PDF]

Mol Genet Genomic Med
Mohd Dali NS, Aziz NA, Zulkifle MF, Zamri DA, Kamaluddin NR, Yeoh SL, Ho BL, Din ND, Ab Ghani AS, Wan Hassan WAH, Zakaria Z, Esa E, Mat Yusoff Y.   +12 more
europepmc   +1 more source

Gene signatures characterizing driver mutations in lung squamous carcinoma are predictive of the progression of pre‐cancer lesions

International Journal of Cancer, EarlyView.
What's New? Lung squamous cell carcinoma (LUSC) is more aggressive than lung adenocarcinoma, and is most often diagnosed at an advanced stage. Here, the authors evaluated gene expression data from LUSC tumors and came up with gene signatures for 34 genetic abnormalities whose expression changes throughout different precancerous stages. Several of these
Yupei Lin, Venugopalareddy Mekala, Jianrong Li, Xiang Wang, Muhammad Aminu, Jia Wu, Jianjun Zhang, Robert Taylor Ripley, Christopher I. Amos, Chao Cheng   +9 more
wiley   +1 more source

Quinacrine Bands in Isolated Chromosomes

CYTOLOGIA, 1976
Wray, Wayne, Stefos, Katherine
openaire   +3 more sources

Trisomy 8 clonal expansion during disease progression and azacitidine resistance in VEXAS syndrome: a case report. [PDF]

Front Immunol
Sato K, Zaimoku Y, Kano Y, Kobayashi M, Kazama S, Morikawa T, Kazumoto H, Ishii W, Ueki T, Sumi M, Kobayashi H, Nannya Y, Ogawa S, Ichikawa N.   +13 more
europepmc   +1 more source

Evaluation of Mutation Risk Using Patient‐Derived Organoids in Patients With Lynch Syndrome

International Journal of Cancer, EarlyView.
ABSTRACT Lynch syndrome (LS) is a hereditary cancer predisposition syndrome caused by germline mutation of DNA mismatch repair (MMR) genes, most notably associated with colorectal cancer. Although LS patients face high risk of CRC, risk can vary even among those with the same pathogenic MMR germline mutations. We suggest a functional assay platform for
Youmi Shin, Dong Keon Kim, Yoojeong Seo, Hyeon Hee Lee, Jihye Park, Soo Jung Park, Jae Jun Park, Jae Hee Cheon, Jongwon Oh, Sanghoo Lee, Tae Il Kim   +10 more
wiley   +1 more source

Array Comparative Genomic Hybridization Analysis of Products of Conception in Recurrent Pregnancy Loss for specific anomalies detected by USG. [PDF]

Reprod Fertil
Gajjar K, Patel A, Patel B, Chettiar S, Jhala D.   +4 more
europepmc   +1 more source

Bazi Bushen Capsule restores fertility by targeting mitochondrial health in aging endometrium

iMeta, EarlyView.
Bazi Bushen Capsule (BZBS) mitigates age‐related endometrial dysfunction by activating AMPK − SIRT3 signaling. Luteolin, a key bioactive component, restores mitochondrial homeostasis via PINK1/Parkin−mediated mitophagy and Drp1 inhibition, improving endometrial function and fertility potential.
Shangqi Li, Feng Deng, Hongjuan Niu, Meng Li, Zeyang Lin, Jiayi Ma, Yue Wang, Yueqi Leng, Yunlong Hou, Wenwen Cui, Yang Yu, Heng Pan, Ping Zhou, Rong Li   +13 more
wiley   +1 more source

Characterization of neocentromeric marker chromosome derived from chromosome 11: a rare entity in four patients with acute leukemia. [PDF]

Chromosome Res
Mendlikova I, Brezinova J, Svobodova K, Pavlistova L, Valerianova M, Valka J, Stastna MM, Jonasova A, Zemanova Z, Ransdorfova S.   +9 more
europepmc   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Frequency and Distribution of Incidental Chromosomal Abnormalities Detected by Peripheral Blood Karyotyping: A Retrospective Study. [PDF]

Genet Res (Camb)
Zhang Y, Bai Z, Li R, Yang H, Wang J, Chen Y.   +5 more
europepmc   +1 more source