Results 201 to 210 of about 27,794 (295)

GATA1 Transcriptionally Upregulates LMCD1, Promoting Ferroptosis in Sepsis‐Associated Acute Kidney Injury Through the Hippo/YAP Pathway

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Sepsis‐associated acute kidney injury (SA‐AKI) is associated with morbidity and mortality. Ferroptosis is associated with the pathophysiology of SA‐AKI. Here, we investigated the role of LIM and cysteine‐rich domain 1 (LMCD1) in the regulation of ferroptosis during SA‐AKI progression.
You‐Qi Zhang   +5 more
wiley   +1 more source

Derivative Complex Small Supernumerary Marker Chromosomes (sSMC) Involving Chromosomes 2 and 15-A Novel Report. [PDF]

open access: yesClin Case Rep
Alayed Y   +8 more
europepmc   +1 more source

Long Noncoding RNA TOB1‐AS1 Represses Cervical Cancer Cell Proliferation, Invasion, and Migration via the MicroRNA‐27a‐3p/Thioredoxin‐Interacting Protein Molecular Axis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Cervical cancer (CC) remains a major global health concern, particularly due to its aggressive nature and limited treatment options in advanced stages. Long noncoding RNA (lncRNA) TOB1‐AS1 has been proposed as a tumor suppressor, yet its regulatory mechanism in CC remains unclear.
Yang Wang   +4 more
wiley   +1 more source

Vitexin Attenuates the Growth and Glycolysis of Acute Myeloid Leukemia Cells by Suppressing the HIF‐1α‐Modulated YAP Pathway Under Hypoxic Conditions

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Vitexin, an apigenin flavone glycoside, exhibits antitumor activity against various cancers including leukemia. Hypoxia enhances glycolysis, thereby promoting tumor growth. In this study, we aimed to explore the effects of vitexin on hypoxia‐induced growth and glycolysis in acute myeloid leukemia (AML) cells and determine the underlying ...
Ping Wang   +4 more
wiley   +1 more source

Chromosomal abnormalities of mesenchymal stromal cells in hematological malignancies. [PDF]

open access: yesOncogene
Lisboa MO   +5 more
europepmc   +1 more source

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