Harnessing bacterial extracellular vesicles for bone and cartilage organoids
This review presents bacterial extracellular vesicles (BEVs) as programmable bioactive regulators for bone and cartilage organoids by delivering functional cargos that modulate skeletal remodeling. It highlights key engineering strategies and future directions to advance next‐generation organoid models for bone aging related diseases.
Han Liu +8 more
wiley +1 more source
Regulation of Leishmania surface coat proteins by the nuclear protein ESB1. [PDF]
Arias Del Angel JA +4 more
europepmc +1 more source
ABSTRACT Heat stress (HS) is an increasing threat to male reproductive health, disrupting spermatogenesis through complex and interdependent cellular responses within the seminiferous epithelium. Although excessive reactive oxygen species (ROS) production is a hallmark of HS, ROS also act as central regulators of cell fate decisions beyond their role ...
Ribrio Ivan Tavares Pereira Batista
wiley +1 more source
Generational variation and stabilization in resynthesized allotetraploid Brassica juncea derived from diploid progenitors B. rapa and B. nigra. [PDF]
Tripathi S +12 more
europepmc +1 more source
Modulation of Epigenetic Control by Advanced Molecular Tweezers
Tailored dimeric molecular tweezers recognize the DNA‐binding part of Histone H4 and interrupt the essential histone‐DNA interaction. ABSTRACT This work addresses the question if supramolecular systems can be tailored to interfere with posttranslational modifications (PTM) and epigenetics.
My‐Hue‐Le +9 more
wiley +1 more source
Transcriptome and metabolome profiling uncover phenotypic divergence of gigantic and dwarf mutant genotypes in induced Pakchoi autotetraploids. [PDF]
Tang W, Zheng J, Sun C, Pan Q.
europepmc +1 more source
Oogenesis and germinal bed morphology of the brown anole (A. sagrei)
Abstract Background The brown anole is a model species of the genus Anolis, a squamate (encompassing lizards and snakes) group widely studied in evolutionary, behavioral, and developmental biology. Full genome annotation, the establishment of gene editing techniques, and comprehensive description of reproductive tract morphology and embryogenesis in ...
Bonnie K. Kircher +12 more
wiley +1 more source
Isolating and Validating Fibroblast-like Cells from the Skeletal Muscle of the Siamese Crocodile (<i>Crocodylus siamensis</i>). [PDF]
Akrimajirachoote N +7 more
europepmc +1 more source
Abstract Background The promoters and enhancers of heat shock genes, such as the 1.5‐kb promoter of the zebrafish hsp70l gene, are valuable tools for temporal activation of transgenes. It has been widely purported that heat shock treatments result in ubiquitous expression of hsp70l‐driven transgenes.
Jong‐Su Park, Xiangyun Wei
wiley +1 more source
A two-stage screening approach integrated with GWAS for rare phenotypes such as spontaneous haploid genome doubling in maize. [PDF]
Fakude M +7 more
europepmc +1 more source

