Results 241 to 250 of about 3,192,378 (312)

Decoding chromatin-associated RNA (caRNA) interaction networks: from genome-wide dynamic capture to epigenetic mechanisms in plants and animals. [PDF]

Epigenetics
Liu C, Li W, Lv Q, Su R.
europepmc   +1 more source

TP53 Loss Elevates NF‐κB‐IFN‐β‐MHC‐Ia Signaling to Promote NK Cell Resistance in Osteosarcoma

Advanced Science, EarlyView.
TP53 loss in a transforming or osteosarcoma cell promotes cytosolic DNA accumulation, activating NF‐κB‐dependent IFN‐β production. Autocrine IFN‐β signaling increases cell‐surface HLA‐Ia expression, strengthens inhibitory KIR signaling in natural killer cells, and thereby enables the affected cell to evade NK cell‐mediated cytotoxicity.
Guihui Qin, Cheung Kwan Yeung, Ye Yi, Dejin Zheng, Miaoman Ye, Chi‐Chong Chio, Jinjie Wu, Siyi Fu, Chu‐Xia Deng, Ren‐He Xu   +9 more
wiley   +1 more source

Matrix Rigidity Mechanoprimes Microglia for Inflammation Through Cytoskeletal‐to‐Nuclear Signaling and 3D Spatio‐Epigenomic Remodeling

Advanced Science, EarlyView.
Pathological tissue rigidity mechanoprimes microglia by enhancing actin cytoskeleton–nucleus coupling and chromatin opening at rigidity‐responsive cis‐regulatory elements (mechanoCREs). Subsequent NF‐κB/p65 signaling converges on this permissive regulatory state to amplify inflammatory gene expression and microglial activation.
Yu Xuan Meng, Jaegeon Joo, Yu Meng Li, Cheng Ji Li, Ali Taghizadeh, Seung Jae Shin, Buuvee Bayarkhangai, Tae‐Woo Ha, Sak Lee, Jaewoo Chung, Bo‐Eun Yoon, Hye Sung Kim, Inkyung Jung, Jung‐Hwan Lee, Kam W. Leong, Hae‐Won Kim   +15 more
wiley   +1 more source

Application of artificial intelligence in identification of chromosome aberration

Zhiye weisheng yu yingji jiuyuan
LIU Huasen
doaj   +1 more source

Molecular cytogenetic analysis of some Picea species from Eurasia and East Asia. [PDF]

Vavilovskii Zhurnal Genet Selektsii
Goryachkina OV, Badaeva ED, Shcherban AB, Muratova EN.   +3 more
europepmc   +1 more source

DDX21 Enhances Radiosensitivity in Head and Neck Squamous Cell Carcinoma by Suppressing MK2‐Mediated DNA Damage Response

Advanced Science, EarlyView.
DDX21 suppresses MK2 activation by directly inhibiting Thr334 phosphorylation in a p38‐independent manner, thereby impairing DNA damage response. Clinically, patients with well‐differentiated tumors exhibiting high DDX21 expression are more likely to benefit from adjuvant radiotherapy, whereas those with low DDX21 levels are predisposed to ...
Tianru Yang, Ting Shen, Yanfang Qiu, Wei Zhang, Ziran Zheng, Jiayi Sun, Yuedi Yao, Mianfeng Yao, Jiang Li   +8 more
wiley   +1 more source

EasyCen: A Lightweight Framework for Centromere Localisation and Repeat-Organisation Profiling in Telomere-to-Telomere Genomes. [PDF]

Mol Ecol Resour
Lv Y, Li Y, Li J, Mu X.
europepmc   +1 more source

HVSnp: A manually curated database of human SNPS associated with viral infections. [PDF]

Genet Mol Biol
Paganin ACL, Freire CCM.
europepmc   +1 more source

Multi-dimensional identification and quality evaluation of <i>Paris polyphylla</i> cultivated populations using morphological, molecular, cytological and metabolic traits. [PDF]

Front Plant Sci
Jiang J, Qin Y, Yu Z, Chen J, Wang J, Yang S, Liu Y, Liu T.   +7 more
europepmc   +1 more source

Rapid turnover of sex chromosomes is associated with speciation in Neotropical armored catfish Harttia (Siluriformes, Loricariidae). [PDF]

Biol Direct
Sassi FMC, de Souza FHS, Perez MF, Shams F, Ezaz T, Deon GA, Liehr T, Xu L, Cioffi MB.   +8 more
europepmc   +1 more source