Results 61 to 70 of about 3,192,378 (312)

Detection of chromosome aberrations in metaphase and interphase tumor cells by in situ hybridization using chromosome-specific library probes [PDF]

, 1988
Chromosome aberrations in two glioma cell lines were analyzed using biotinylated DNA library probes that specifically decorate chromosomes 1, 4, 7, 18 and 22 from pter to qter.
Cremer, Thomas, Manuelidis, L., Lichter, Peter, Borden, J., Ward, D. C.   +4 more
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

The creation of new aneuploid lines of the cotton (Gossypium hirsutum L.) with identification of chromosomes by translocation and SSR-markers

Вавиловский журнал генетики и селекции, 2016
The use of monosomic lines significantly increases the effectiveness of molecular-genetic analysis and the development of superior quality breeding lines via substitutions by alien chromosomes.
M. F. Sanamyan, Sh. U. Bobokhujaev, A. X. Makamov, S. G. Achilov, I. Y. Abdurakhmonov   +4 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Chromosome painting and its applications in cultivated and wild rice

BMC Plant Biology, 2018
Background The chromosome-specific probe is a fundamental tool of chromosome painting and has been commonly applied in mammalian species. The technology, however, has not been widely applied in plants due to a lack of methodologies for probe development.
Lili Hou, Meng Xu, Tao Zhang, Zhihao Xu, Weiyun Wang, Jianxiang Zhang, Meimei Yu, Wen Ji, Cenwen Zhu, Zhiyun Gong, Minghong Gu, Jiming Jiang, Hengxiu Yu   +12 more
doaj   +1 more source

Characterization, Identification and Evaluation of Wheat-Aegilops sharonensis Chromosome Derivatives

Frontiers in Plant Science, 2021
Aegilops sharonensis, a wild relative of wheat, harbors diverse disease and insect resistance genes, making it a potentially excellent gene source for wheat improvement. In this study, we characterized and evaluated six wheat-A.
Xiaolu Wang, Xiaolu Wang, Xiaolu Wang, Zhihui Yu, Hongjin Wang, Jianbo Li, Jianbo Li, Jianbo Li, Ran Han, Ran Han, Ran Han, Wenjing Xu, Wenjing Xu, Wenjing Xu, Guangrong Li, Jun Guo, Jun Guo, Jun Guo, Yan Zi, Yan Zi, Yan Zi, Faji Li, Faji Li, Faji Li, Dungong Cheng, Dungong Cheng, Dungong Cheng, Aifeng Liu, Aifeng Liu, Aifeng Liu, Haosheng Li, Haosheng Li, Haosheng Li, Zujun Yang, Jianjun Liu, Jianjun Liu, Jianjun Liu, Cheng Liu, Cheng Liu, Cheng Liu   +39 more
doaj   +1 more source

FISH mapping and identification of canine chromosomes [PDF]

Journal of Heredity, 1999
The karyotype of the domestic dog (Canis familiaris) is widely accepted as one of the most difficult mammalian karyotypes to work with. The dog has a total of 78 chromosomes; all 76 autosomes are acrocentric in morphology and show only a gradual decrease in length. Standardization of the canine karyotype has been performed in two stages.
M, Breen, C F, Langford, N P, Carter, N G, Holmes, H F, Dickens, R, Thomas, N, Suter, E J, Ryder, M, Pope, M M, Binns   +9 more
openaire   +2 more sources

The inexorable spread of a newly arisen neo-Y chromosome [PDF]

, 2008
This work was financially supported by a Natural Environment Research Council grant to RAN. (NER-B-S-2003-00859) and a studentship from Queen Mary University of London to PV.A newly arisen Y-chromosome can become established in one part of a species ...
Keller, Irene, Irene Keller, Keller Irene, Veltsos, Paris, Nichols Richard A., Veltsos, P, Nichols, Richard A., Veltsos Paris, Richard A. Nichols, Nichols, R A, Richard A Nichols, Keller, I, Nichols, RA, Paris Veltsos, Veltsos, Paris (author), P Veltsos, Keller, Irene (author), Nichols, Richard A. (author)   +17 more
core   +2 more sources

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Sequential cross-species chromosome painting among river buffalo, cattle, sheep and goat: a useful tool for chromosome abnormalities diagnosis within the family Bovidae. [PDF]

PLoS ONE, 2014
The main goal of this study was to develop a comparative multi-colour Zoo-FISH on domestic ruminants metaphases using a combination of whole chromosome and sub-chromosomal painting probes obtained from the river buffalo species (Bubalus bubalis, 2n = 50 ...
Alfredo Pauciullo, Angela Perucatti, Gianfranco Cosenza, Alessandra Iannuzzi, Domenico Incarnato, Viviana Genualdo, Dino Di Berardino, Leopoldo Iannuzzi   +7 more
doaj   +1 more source