Results 271 to 280 of about 194,576 (309)
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Standard maps of chromosome 10
Annals of Human Genetics, 1990SUMMARYTo achieve consensus more exact definitions of genetical maps are required, of which standard, comprehensive and skeletal might be some. A standard genetic map gives distance from pter in centimorgans (cM), uses the international nomenclature for assigned loci, is sex‐specific, and allows as well as possible for interference and typing errors. A
Morton, Newton, Collins, Andrew
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Linkage maps of human chromosomes
Genome, 1989Finding the chromosomal location of human genes that heretofore have been defined solely by phenotypes, in particular clinical phenotypes that are transmitted in Mendelian fashion in families, is an early and often crucial step in the process of identifying the molecular basis of a disease.
Peter O'Connell +5 more
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Annals of Human Genetics, 1984
SummaryThe genetic map of chromosome 1 reported by Keats, Morton & Rao (1981) has been updated using recent recombination data and regional assignments from the Galton Laboratory (King, 1982a) and from the current literature. A maximum likelihood mapping technique using pairwise recombination data without a chiasma map was developed, based on the ...
Stephanie L. Sherman +3 more
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SummaryThe genetic map of chromosome 1 reported by Keats, Morton & Rao (1981) has been updated using recent recombination data and regional assignments from the Galton Laboratory (King, 1982a) and from the current literature. A maximum likelihood mapping technique using pairwise recombination data without a chiasma map was developed, based on the ...
Stephanie L. Sherman +3 more
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1991
In order to map the human genome, the gene, as indicated by expressed gene products, abnormal phenotypes, or markers representing it, must first be assigned to a particular chromosome (from Greek, khroma, colour, and soma, body). For some genes, analysis of pedigree data alone may confirm their localisation.
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In order to map the human genome, the gene, as indicated by expressed gene products, abnormal phenotypes, or markers representing it, must first be assigned to a particular chromosome (from Greek, khroma, colour, and soma, body). For some genes, analysis of pedigree data alone may confirm their localisation.
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Advances in Y chromosome mapping
Current Opinion in Obstetrics and Gynaecology, 1999The human Y chromosome has long been recognized as being responsible for sex determination. In fact, it also encodes more than 30 genes and gene families that participate in a variety of cellular functions, including bone development, tooth growth, and spermatogenesis.
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A mapping function for human chromosomes
Annals of Human Genetics, 1976The available simple mapping functions are surveyed, and a new mapping function that provides for positive interference within chromosome arms and no interference across the centromere is proposed, together with the corresponding formula for centromeric linkage.
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Mapping the human Y chromosome
Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1988This paper reviews past and present trends in mapping the human Y chromosome. So far, mapping has essentially used a combination of cytogenetic and molecular analyses of Y-chromosomal anomalies and sex reversal syndromes. This deletion mapping culminated recently in the isolation of the putative sex-determining locus TDF
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Human Genetics, 1983
Starting with the male chiasma distribution for chromosome 2, a significantly better fit is obtained to lod scores for the X chromosome if terminalization of distal chiasmata is assumed. The linkage data are not consistent with a uniform distribution of chiasmata, absence of terminalization, or restriction of terminalization to the distal band.
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Starting with the male chiasma distribution for chromosome 2, a significantly better fit is obtained to lod scores for the X chromosome if terminalization of distal chiasmata is assumed. The linkage data are not consistent with a uniform distribution of chiasmata, absence of terminalization, or restriction of terminalization to the distal band.
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The map of the cell is in the chromosome
Current Opinion in Genetics & Development, 1997Antoine Danchin, Alain Hénaut
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