Results 101 to 110 of about 10,937,438 (374)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Morfo-anatomia de plântulas e número cromossômico de Cybistax antisyphilitica (Mart.) Mart. (Bignoniaceae) Seedling morpho-anatomy and chromosome number of Cybistax antisyphilitica (Mart.) Mart. (Bignoniaceae)

Acta Botânica Brasílica, 2008
Plântulas de Cybistax antisyphilitica (ipê-verde), espécie arbórea que ocorre no Estado de São Paulo, Brasil, foram estudadas morfoanatomicamente e citogeneticamente. As plântulas são eudicotiledôneas, fanerocotiledonares e epigéias.
Flavia Aparecida Ortolani, Márcia Fiorese Mataqueiro, José Roberto Moro, Fabíola Vitti Moro, Carlos Ferreira Damião Filho   +4 more
doaj   +1 more source

A step‐by‐step protocol for meiotic chromosome counts in flowering plants: A powerful and economical technique revisited

Applications in Plant Sciences, 2020
Premise Counting chromosomes is a fundamental botanical technique, yet it is often intimidating and increasingly sidestepped. Once mastered, the basic protocol can be applied to a broad range of taxa and research questions.
Michael D. Windham, Kathleen M. Pryer, Derick B. Poindexter, Fay‐Wei Li, Carl J. Rothfels, James B. Beck   +5 more
doaj   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Detection of complete and partial chromosome gains and losses by comparative genomic in situ hybridization [PDF]

, 1993
Comparative genomic in situ hybridization (CGH) provides a new possibility for searching genomes for imbalanced genetic material. Labeled genomic test DNA, prepared from clinical or tumor specimens, is mixed with differently labeled control DNA prepared ...
Cremer, Thomas, Döhner, Hartmut, Joos, Stefan, Kovacs, Gyula, Lichter, Peter, Manoir, Stanislas du, Popp, Susanne, Robert-Nicoud, Michel, Schröck, Evelin, Speicher, Michael R.   +9 more
core   +1 more source

Genome size, chromosome number, and rDNA organisation in Algerian populations of Artemisia herba-alba (Asteraceae), a basic plant for animal feeding facing overgrazing erosion

Anales del Jardín Botánico de Madrid, 2016
Artemisia herba-alba is a largely-distributed and often landscape-dominating taxon in arid areas of the Mediterranean and Irano-Turanian regions. In Algeria, in 2010 its communities covered 10% of the steppe territory, but its populations have been ...
Youcef Bougoutaia, Sònia Garcia, Teresa Garnatje, Meriem Kaid-Harche, Joan Vallès   +4 more
doaj   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Biomarkers of leukemia risk: benzene as a model. [PDF]

, 1998
Although relatively rare, leukemias place a considerable financial burden on society and cause psychologic trauma to many families. Leukemia is the most common cancer in children.
Smith, MT, Zhang, L
core   +3 more sources

MEIOSIS: HOW TO HALVE THE CHROMOSOME NUMBER

Вавиловский журнал генетики и селекции, 2014
The notion of meiosis has been changed and refined for over a century since the discovery of this complicated way of cell division. Its success depends on precise time and space orchestration of many processes, such as chromosome replication, packaging ...
A. A. Torgasheva
doaj  

Maximum likelihood inference implies a high, not a low, ancestral haploid chromosome number in Araceae, with a critique of the bias introduced by 'x'.

Annals of Botany, 2012
BACKGROUND AND AIMS For 84 years, botanists have relied on calculating the highest common factor for series of haploid chromosome numbers to arrive at a so-called basic number, x.
N. Cusimano, Aretuza Sousa, S. Renner
semanticscholar   +1 more source