Results 101 to 110 of about 11,109,446 (394)
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Ecology and Evolution, 2021 In the species‐rich genus Impatiens, few natural hybrids are known, even though closely related species often occur sympatrically. In this study, we aim to bridge the gap between micro‐ and macro‐evolution to disentangle pre‐ and postzygotic mechanisms ...
Stefan Abrahamczyk +6 more
doaj +1 more source
Inference of plasmid copy number mean and noise from single cell gene expression data
, 2010 Plasmids are extra-chromosomal DNA molecules which code for their own replication. We previously reported a setup using genes coding for fluorescent proteins of two colors that allowed us, using a simple model, to extract the plasmid copy number noise in
Chatenay, Didier +3 more
core +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Morphometric Variations Between Triploid and Diploid Clarias gariepinus (Burchell, 1822)
Croatian Journal of Fisheries, 2017 Several scientific methods have been described in the identification of triploid fish. However, many of these methods are not applicable for routine management purposes due to their complexity and cost.
Normala Jalil +6 more
doaj +1 more source
Karyotypes of six previously unstudied European mealybugs (Homoptera: Pseudococcidae)
Comparative Cytogenetics, 2010 Phenacoccus peruvianus Granada de Willink, 2007, Ph. prope avenae Borchsenius, 1949, Ph. hordei (Lindeman, 1886), Вalanococcus boratynskii Williams, 1962, Trionymus radicum (Newstead, 1895), Rhizoecus halophilus (Hardy, 1868) were studied ...
Ilya Gavrilov-Zimin, I Trapeznikova
doaj +1 more source
, 2020 X‐chromosome inactivation ensures dosage compensation between the sexes in mammals by randomly choosing one out of the two X chromosomes in females for inactivation.
Mutzel, V., Schulz, E.
core +1 more source
Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source
Amplification of the androgen receptor may not explain the development of androgen-independent prostate cancer [PDF]
, 2001 Objective To examine the role of androgen receptor (AR) gene amplification and aneusomy of the X chromosome in the development of antiandrogen-resistant prostate cancer.
Bartlett, J.M.S. +5 more
core +1 more source
Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source