Chromosome number and karyotype of the endangered Amazonian woody Centrolobium paraense Tul. species [PDF]
Centrolobium paraense Tul., popularly known in Brazil as “pau-rainha”, is a species with a high timberpotential, presently endangered due to deforestation of the Amazonian region and indiscriminate wood extraction.
Nair Dahmer+2 more
doaj
The family Malpighiaceae presents species with different habits, fruit types and cytological characters. Climbers are considered the most derived habit, followed, respectively, by the shrubby and arboreal ones. The present study examines the relationship
Ricardo A. Lombello+1 more
doaj +1 more source
A novel three-colour fluorescence in situ hybridization approach for the detection of t(7;12)(q36;p13) in acute myeloid leukaemia reveals new cryptic three way translocation t(7;12;16) [PDF]
© 2013 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).The t(7;12)(q36;p13 ...
Abdulbasit Naiel+14 more
core +2 more sources
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides+13 more
wiley +1 more source
Chromosome numbers, meiotic behavior and pollen fertility in a collection of Paspalum nicorae Parodi accessions [PDF]
Chromosome number, meiotic behavior and pollen viability were evaluated in a collection of 53 Paspalumnicorae Parodi accessions, which are part of a breeding project of the species.
Camila Aparecida de Oliveira dos Reis+2 more
doaj
Chromosome positioning is largely unaffected in lymphoblastoid cell lines containing emerin or A-type lamin mutations [PDF]
Gene-poor human chromosomes are reproducibly found at the nuclear periphery in proliferating cells. There are a number of inner nuclear envelope proteins that may have roles in chromosome location and anchorage, e.g. emerin and A-type lamins.
Bridger, JM+3 more
core +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero+8 more
wiley +1 more source
Cytogenetics of Hypericum caprifoliatum Cham. & Schltdl. (Clusiaceae) populations and other species of the genus [PDF]
Chromosome numbers and meiotic behavior are presented for the first time for Hypericum caprifoliatum(2n=48), H. cf carinatum (2n=48) and H. polyanthemum (2n= 32) and confirmed the H. perforatum (2n=32) number.Chromosomes are very small (ca.
Danielle Almeida+3 more
doaj
The Mbd1-Atf7ip-Setdb1 pathway contributes to the maintenance of X chromosome inactivation. [PDF]
BackgroundX chromosome inactivation (XCI) is a developmental program of heterochromatin formation that initiates during early female mammalian embryonic development and is maintained through a lifetime of cell divisions in somatic cells.
Bonora, Giancarlo+5 more
core +3 more sources
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li+12 more
wiley +1 more source