Results 31 to 40 of about 405,684 (326)
Nature Communications, 2022 Trans-chromosomic (Tc) mice have helped the development of therapeutic antibodies, but chromosome instability limits its application. Here the authors develop a new line of Tc mice with full human Ig heavy and kappa loci integrated into the mouse ...
Hiroyuki Satofuka +17 more
doaj +1 more source
mBio, 2020 Cell division requires proper spatial coordination with the chromosome, which undergoes dynamic changes during chromosome replication and segregation. FtsZ is a bacterial cytoskeletal protein that assembles into the Z-ring, providing a platform to build ...
Shogo Ozaki, Urs Jenal, Tsutomu Katayama
doaj +1 more source
Reduced chromosome aberration complexity in normal human bronchial epithelial cells exposed to low-LET γ-rays and high-LET α-particles [PDF]
, 2013 This article is made available through the Brunel Open Access Publishing Fund.Copyright © 2013 The Author(s). Purpose: Cells of the lung are at risk from exposure to low and moderate doses of ionizing radiation from a range of environmental and medical ...
Anderson, RM +3 more
core +2 more sources
Getting your chromosomes organized [PDF]
Nature Reviews Microbiology, 2019 This study reports that the archaeal chromosome is organized into two compartments with differential gene expression activities that are maintained by a novel Sulfolobus-encoded structural maintenance of chromosomes protein.
openaire +2 more sources
Frontiers in Microbiology, 2021 The alpha-proteobacterium Zymomonas mobilis is a promising biofuel producer, based on its native metabolism that efficiently converts sugars to ethanol. Therefore, it has a high potential for industrial-scale biofuel production.
Katsuya Fuchino +3 more
doaj +1 more source
Chromosome Segregation Is Biased by Kinetochore Size [PDF]
, 2018 Chromosome missegregation during mitosis or meiosis is a hallmark of cancer and the main cause of prenatal death in humans. The gain or loss of specific chromosomes is thought to be random, with cell viability being essentially determined by selection ...
Aguiar, P +8 more
core +2 more sources
Chromosome Centromeres: Structural and Analytical Investigations with High Resolution Scanning Electron Microscopy in Combination with Focused Ion Beam Milling [PDF]
, 2009 Whole mount mitotic metaphase chromosomes of different plants and animals were investigated with high resolution field emission scanning electron microscopy (FESEM) to study the ultrastructural organization of centromeres, including metacentric ...
Schroeder-Reiter, E., Wanner, Gerhard
core +1 more source
Stretching the Rules: Monocentric Chromosomes with Multiple Centromere Domains [PDF]
, 2012 The centromere is a functional chromosome domain that is essential for faithful chromosome segregation during cell division and that can be reliably identified by the presence of the centromere-specific histone H3 variant CenH3.
A Kawabe +45 more
core +4 more sources
Organization of the Chromosome
Cold Spring Harbor Symposia on Quantitative Biology, 1956 The observational and experimental results presented here constitute another chapter in a continuing research program that is directed toward an understanding of patterns of organization of chromosomal materials. Evidence has been sought over the years at various levels of analysis, beginning with descriptive cytology, progressing into the areas of ...
B P, KAUFMANN, M R, MCDONALD
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BMC Genomics, 2018 Background Due to the predominant usage of short-read sequencing to date, most bacterial genome sequences reported in the last years remain at the draft level.
Friedhelm Pfeiffer +6 more
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