Specific staining of human chromosomes in Chinese hamster x man hybrid cell lines demonstrates interphase chromosome territories [PDF]
In spite of Carl Rabl's (1885) and Theodor Boveri's (1909) early hypothesis that chromosomes occupy discrete territories or domains within the interphase nucleus, evidence in favor pf this hypothesis has been limited and indirect so far in higher plants ...
AB Murray+34 more
core +1 more source
A conserved filamentous assembly underlies the structure of the meiotic chromosome axis. [PDF]
The meiotic chromosome axis plays key roles in meiotic chromosome organization and recombination, yet the underlying protein components of this structure are highly diverged.
Caballero, Iracema+10 more
core +4 more sources
Chromosome Oscillations in Mitosis [PDF]
Successful cell division requires a tight regulation of chromosome motion via the activity of molecular motors. Many of the key players at the origin of the forces generating the movement have been identified, but their spatial and temporal organization ...
A. P. Joglekar+8 more
core +2 more sources
The condensin complex is required for proper spindle assembly and chromosome segregation in Xenopus egg extracts. [PDF]
Chromosome condensation is required for the physical resolution and segregation of sister chromatids during cell division, but the precise role of higher order chromatin structure in mitotic chromosome functions is unclear.
Deehan, Renee+3 more
core +4 more sources
Background Due to the predominant usage of short-read sequencing to date, most bacterial genome sequences reported in the last years remain at the draft level.
Friedhelm Pfeiffer+6 more
doaj +1 more source
Prime movers : mechanochemistry of mitotic kinesins [PDF]
Mitotic spindles are self-organizing protein machines that harness teams of multiple force generators to drive chromosome segregation. Kinesins are key members of these force-generating teams.
A Blangy+184 more
core +1 more source
Iterative Correction of Hi-C Data Reveals Hallmarks of Chromosome Organization
Extracting biologically meaningful information from chromosomal interactions obtained with genome-wide chromosome conformation capture (3C) analyses requires the elimination of systematic biases.
Maxim Imakaev+7 more
semanticscholar +1 more source
Spatial organization of bacterial chromosomes [PDF]
Bacterial chromosomes are organized in stereotypical patterns that are faithfully and robustly regenerated in daughter cells. Two distinct spatial patterns were described almost a decade ago in our most tractable model organisms. In recent years, analysis of chromosome organization in a larger and more diverse set of bacteria and a deeper ...
David Z. Rudner, Xindan Wang
openaire +3 more sources
Mechanisms of Chromosome Folding and Nuclear Organization: Their Interplay and Open Questions.
Microscopy and genomic approaches provide detailed descriptions of the three-dimensional folding of chromosomes and nuclear organization. The fundamental question is how activity of molecules at the nanometer scale can lead to complex and orchestrated ...
L. Mirny, J. Dekker
semanticscholar +1 more source
Multi layer chromosome organization through DNA bending, bridging and extrusion [PDF]
All living cells have to master the extraordinarily extended and tangly nature of genomic DNA molecules in particular during cell division when sister chromosomes are resolved from one another and confined to opposite halves of a cell.
Gruber, S.
core +2 more sources