Results 191 to 200 of about 199,391 (364)

Genome Mining Enabled by Biosynthetic Characterization Uncovers a Class of Benzoxazolinate‐Containing Natural Products in Diverse Bacteria

open access: yesAngewandte Chemie, Volume 134, Issue 51, December 19, 2022., 2022
Benzoxazolinate is a rare bis‐heterocyclic moiety that interacts with proteins and DNA. It was found that a putative acyl AMP‐ligase mediates the last cyclization step to afford benzoxazolinate. The enzyme was then used as a probe for genome mining, which led to the discovery of a new class of benzoxazolinate‐containing compounds in diverse bacteria ...
Yi‐Ming Shi   +12 more
wiley   +2 more sources

The genome-wide multi-layered architecture of chromosome pairing in early Drosophila embryos. [PDF]

open access: yesNat Commun, 2019
Erceg J   +16 more
europepmc   +1 more source

Single‐Cell Atlas Reveals Tumorigenic Profiles and Immune Dynamics of Adrenal Incidentalomas

open access: yesAdvanced Science, EarlyView.
Single‐cell RNA sequencing reveals cellular heterogeneity in adrenal incidentalomas, identifying distinct tumor cell populations. Clusterin is recognized as a biomarker for adrenocortical tumors, correlating with established markers. MYCN‐positive clusters in pheochromocytomas indicated poorer survival.
Meng Wang   +18 more
wiley   +1 more source

Characterization of Button Loci that Promote Homologous Chromosome Pairing and Cell-Type-Specific Interchromosomal Gene Regulation. [PDF]

open access: yesDev Cell, 2019
Viets K   +13 more
europepmc   +1 more source

Revealing the Transcriptional and Metabolic Characteristics of Sebocytes Based on the Donkey Cell Transcriptome Atlas

open access: yesAdvanced Science, EarlyView.
In this study, a comprehensive single‐cell transcriptome atlas of the Dezhou donkey, encompassing 20 tissues and 275 050 cells, is constructed. Through cross‐species and cross‐tissue analyses, distinct transcriptional patterns in donkey sebocytes are identified.
Yu Tian   +11 more
wiley   +1 more source

Touch-and-Go Pairing in Chromosomes [PDF]

open access: yesProceedings of the National Academy of Sciences, 1940
openaire   +3 more sources

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