Results 221 to 230 of about 199,391 (364)

Antler tine homologies and cervid systematics: A review of past and present controversies with special emphasis on Elaphurus davidianus

open access: yesThe Anatomical Record, Volume 306, Issue 1, Page 5-28, January 2023., 2023
Abstract Antlers are the most conspicuous trait of cervids and have been used in the past to establish a classification of their fossil and living representatives. Since the availability of molecular data, morphological characters have generally become less important for phylogenetic reconstructions.
Nicola S. Heckeberg   +2 more
wiley   +1 more source

Single‐Cell Analysis Clarifies Pathological Heterogeneity in Tenosynovial Giant Cell Tumor and Identifies Biomarkers for Predicting Disease Recurrence

open access: yesAdvanced Science, EarlyView.
MP3 tumor cells, a specific subpopulation of tumor cells in D‐TGCT, regulated the differentiation of CD34+ Fbs into MMP3+ Fbs and APOE+ Fbs through COL6A3 − (ITGAV + ITGB8) interaction. APOE+ Fbs activated IL‐1B+CCL20+ Mφs through the CXCL12/CXCR4 axis. IL‐1B+CCL20+ Mφs and MMP3+ Fbs participated in the local invasion of D‐TGCT.
Yubin Xie   +15 more
wiley   +1 more source

Embryonic cranial cartilage defects in the Fgfr3Y367C/+ mouse model of achondroplasia

open access: yesThe Anatomical Record, EarlyView., 2023
Abstract Achondroplasia, the most common chondrodysplasia in humans, is caused by one of two gain of function mutations localized in the transmembrane domain of fibroblast growth factor receptor 3 (FGFR3) leading to constitutive activation of FGFR3 and subsequent growth plate cartilage and bone defects.
Susan M. Motch Perrine   +9 more
wiley   +1 more source

Physical maps of the six smallest chromosomes of Saccharomyces cerevisiae at a resolution of 2.6 kilobase pairs. [PDF]

open access: bronze, 1993
Linda Riles   +8 more
openalex   +1 more source

The Hypoxia‐Associated High‐Risk Cell Subpopulation Distinctly Enhances the Progression of Glioma

open access: yesAdvanced Science, EarlyView.
This study suggests the potential roles of a novel hypoxia‐associated CDC20+KIF20A+PTTG1+ cell subpopulation in glioma progression. This high‐risk glioma cell subpopulation is therapeutically vulnerable to glioma progression and may play important roles in glioma standard‐of‐care therapeutic resistance.
Quan Wan   +13 more
wiley   +1 more source

Identification and Biological Evaluation of a Novel CLK4 Inhibitor Targeting Alternative Splicing in Pancreatic Cancer Using Structure‐Based Virtual Screening

open access: yesAdvanced Science, EarlyView.
Pancreatic cancer is a highly aggressive malignancy with limited treatment options. CLK4 regulates alternative splicing, contributing to cancer progression. This study establishes a computational model to identify CLK4 inhibitors, leading to compound 150441 (IC50: 21.4 nm).
Chun‐Lin Yang   +13 more
wiley   +1 more source

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