Perspectives on the utilization of <i>Aegilops</i> species containing the U genome in wheat breeding: a review. [PDF]
Badaeva ED +4 more
europepmc +1 more source
Ancestral Chromosome-Level Assemblies Reveal Posthybridization Genome Evolution in the New Mexico Whiptail Lizard (Aspidoscelis neomexicanus). [PDF]
Ho DV +11 more
europepmc +1 more source
ABSTRACT Bladder exstrophy and epispadias complex (BEEC) is one of the most severe congenital malformations of the urogenital tract, significantly impacting continence, sexual function, and renal function. To date, the only recurrent genetic aberration identified is the 22q.11.2 microduplication, but several candidate regions and genes including ...
Agneta Nordenskjöld +9 more
wiley +1 more source
Prenatal Evaluation of RNU4‐2 Variants in Fetuses With Central Nervous System Anomalies
ABSTRACT Fetal central nervous system (CNS) anomalies are among the most common congenital malformations, yet the overall prenatal diagnostic yield of current genetic testing remains below 40%. Variants in RNU4‐2, a non‐coding gene encoding the U4 small nuclear RNA (snRNA), have recently been linked to a novel highly recurrent dominant ...
Yiyao Chen +13 more
wiley +1 more source
A diverse satellite DNA repertoire in <i>Limnoperna fortunei</i>: insights into genome structure and chromosomal organization. [PDF]
Castro JP +5 more
europepmc +1 more source
Construction of pathogenic Sec16a mutation mouse model using CRISPR/Cas9
Yaqiang Hu et al. engineered a pathogenic Sec16a mutant mouse model using CRISPR/Cas9 technology. They observed that the Sec16a mutant mice displayed diminished learning and memory capabilities, along with a limb‐clasping phenotype upon tail suspension.
Yaqiang Hu +6 more
wiley +1 more source
Non-Canonical Male Meiosis in a Marine Gastropod, <i>Littorina saxatilis</i>. [PDF]
Demin SI +3 more
europepmc +1 more source
Molecular characterization of the A52 murine hepatocellular carcinoma cell line
Hepatocellular carcinoma (HCC) is a poor outcome cancer with limited therapeutic choices. To advance therapeutic development we genetically characterized the A52 murine HCC cell line. We noted genetic changes that match a subset of human HCC and this offers the opportunity to test novel targeted therapies in syngeneic mice.
Rhys Gillman +5 more
wiley +1 more source
Reproductive barriers confirm absence of hybrid speciation and introgression in the Rhodnius pictipes and R. pallescens groups (Hemiptera, Triatominae). [PDF]
Alevi KCC +10 more
europepmc +1 more source

