Results 241 to 250 of about 199,391 (364)
Targeted regulation of pyroptosis to modulate the immune landscape is a novel design strategy for cancer immunotherapy and anti‐inflammatory treatment. Pyroptosis, as a double‐edged sword, underscores the importance of optimizing the design strategy of functional materials and appropriately activating pyroptosis for the effective treatment of diseases.
Luyao Tian+5 more
wiley +1 more source
Chromosome pairing and synapsis during Caenorhabditis elegans meiosis. [PDF]
Rog O, Dernburg AF.
europepmc +1 more source
Telomere-led bouquet formation facilitates homologous chromosome pairing and restricts ectopic interaction in fission yeast meiosis [PDF]
Osami Niwa+2 more
openalex +1 more source
A novel “prof” cocktail therapy is designed. It screens antigens, selects personalized antigen panels, engineers optimized CAR‐Vδ1 T cells, and tests in patient‐derived GBM organoids, offering hope for effective CAR‐T drugs against heterogeneous solid tumors. Abstract Various challenges, including tumor heterogeneity and inadequate T cell infiltration,
Guidong Zhu+12 more
wiley +1 more source
Modeling meiotic chromosome pairing: nuclear envelope attachment, telomere-led active random motion, and anomalous diffusion. [PDF]
Marshall WF, Fung JC.
europepmc +1 more source
MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice [PDF]
Burkhard Kneitz+9 more
openalex +1 more source
Pogostemon cablin Benth. (PCEE) is a promising antiaging agent that inhibits ROS, decreases the senescence‐associated β‐galactosidase (SA‐β‐gal) gene, and maintains telomere length in doxorubicin‐induced 3T3‐L1 fibroblast cells. The researchers extend their gratitude to www.freepik.com for providing Figure telomer.
Teguh Santoso+6 more
wiley +1 more source
Chromosomal Position Effects Reveal Different cis-Acting Requirements for rDNA Transcription and Sex Chromosome Pairing in Drosophila melanogaster [PDF]
Albert Briscoe, John E. Tomkiel
openalex +1 more source
TP53‐Mutated Myeloid Neoplasms: 2024 Update on Diagnosis, Risk‐Stratification, and Management
ABSTRACT Alterations in the tumor suppressor gene TP53 are common in human cancers and are associated with an aggressive nature. Approximately 8%–12% of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) harbor TP53 mutations (TP53mut) and present immense challenges due to inherent chemoresistance and poor outcomes.
Mithun Vinod Shah+2 more
wiley +1 more source