Results 51 to 60 of about 43,615 (154)

X-inactivation by chromosomal pairing events [PDF]

Genes & Development, 1999
X-inactivation is the coordinated silencing of nearly all genes on one of the two X chromosomes in female mammals. X-inactivation requires the cis-acting Xist gene. The highly unusual properties of Xist and the extremely long distances over which Xist acts have made it difficult to reconcile X-inactivation with other examples of gene regulation.
openaire   +2 more sources

Protein phosphatase 4 promotes chromosome pairing and synapsis, and contributes to maintaining crossover competence with increasing age.

PLoS Genetics, 2014
Prior to the meiotic divisions, dynamic chromosome reorganizations including pairing, synapsis, and recombination of maternal and paternal chromosome pairs must occur in a highly regulated fashion during meiotic prophase.
Aya Sato-Carlton, Xuan Li, Oliver Crawley, Sarah Testori, Enrique Martinez-Perez, Asako Sugimoto, Peter M Carlton   +6 more
doaj   +1 more source

Sex Chromosome Inactivation: The Importance of Pairing [PDF]

Current Biology, 2005
In mammals, the process of making sperm is marked by inactivation of sex chromosomes. Why and how does this happen? The answer apparently lies in whether a chromosome finds a pairing partner. Similar mechanisms in mold and worms reveal a surprising and recurrent theme throughout evolution.
openaire   +2 more sources

Protocol for the Preparation of Arabidopsis Meiotic Chromosome Spreads and Fluorescent in situ Hybridization

Bio-Protocol, 2014
This protocol is a more detailed version of previous protocols (Yang et al., 2011; Bolaños-Villegas et al., 2013) developed for the examination of meiotic chromosome spreads.
Pablo Bolanos-Villegas, Xiaohui Yang, Christopher Makaroff, Guang-Yuh Jauh   +3 more
doaj   +1 more source

MJL-1 is a nuclear envelope protein required for homologous chromosome pairing and regulation of synapsis during meiosis in C. elegans. [PDF]

Sci Adv, 2023
Kim HJ, Liu C, Zhang L, Dernburg AF.
europepmc   +1 more source

The use of the ph1b mutant to induce recombination between the chromosomes of wheat and barley

Frontiers in Plant Science, 2015
Intensive breeding has led to a narrowing in the genetic base of our major crops. In wheat, access to the extensive gene pool residing in its many and varied relatives (some cultivated, others wild) is hampered by the block on recombination imposed by ...
María-Dolores eRey, María-del-Carmen eCalderón, Pilar ePrieto   +2 more
doaj   +1 more source

The Essential Function of SETDB1 in Homologous Chromosome Pairing and Synapsis during Meiosis. [PDF]

Cell Rep, 2021
Cheng EC, Hsieh CL, Liu N, Wang J, Zhong M, Chen T, Li E, Lin H.   +7 more
europepmc   +1 more source

Meiotic Behavior of Achiasmate Sex Chromosomes in the African Pygmy Mouse Mus mattheyi Offers New Insights into the Evolution of Sex Chromosome Pairing and Segregation in Mammals. [PDF]

Genes (Basel), 2021
Gil-Fernández A, Ribagorda M, Martín-Ruiz M, López-Jiménez P, Laguna T, Gómez R, Parra MT, Viera A, Veyrunes F, Page J.   +9 more
europepmc   +1 more source

Pairing of homologous regions in the mouse genome is associated with transcription but not imprinting status.

PLoS ONE, 2012
Although somatic homologous pairing is common in Drosophila it is not generally observed in mammalian cells. However, a number of regions have recently been shown to come into close proximity with their homologous allele, and it has been proposed that ...
Christel Krueger, Michelle R King, Felix Krueger, Miguel R Branco, Cameron S Osborne, Kathy K Niakan, Michael J Higgins, Wolf Reik   +7 more
doaj   +1 more source

Chromosome segregation during spermatogenesis occurs through a unique center-kinetic mechanism in holocentric moth species.

PLoS Genetics
Precise regulation of chromosome dynamics in the germline is essential for reproductive success across species. Yet, the mechanisms underlying meiotic chromosomal events such as homolog pairing and chromosome segregation are not fully understood in many ...
Clio Hockens, Hernan Lorenzi, Tricia T Wang, Elissa P Lei, Leah F Rosin   +4 more
doaj   +1 more source