Results 101 to 110 of about 44,353 (314)

Nonequilibrium polysome dynamics promote chromosome segregation and its coupling to cell growth in Escherichia coli

eLife
Chromosome segregation is essential for cellular proliferation. Unlike eukaryotes, bacteria lack cytoskeleton-based machinery to segregate their chromosomal DNA (nucleoid).
Alexandros Papagiannakis, Qiwei Yu, Sander K Govers, Wei-Hsiang Lin, Ned S Wingreen, Christine Jacobs-Wagner   +5 more
doaj   +1 more source

Genome-wide linkage analyses identify Hfhl1 and Hfhl3 with frequency-specific effects on the hearing spectrum of NIH Swiss mice

BMC Genetics, 2012
Background The mammalian cochlea receives and analyzes sound at specific places along the cochlea coil, commonly referred to as the tonotopic map. Although much is known about the cell-level molecular defects responsible for severe hearing loss, the ...
Keller James M, Noben-Trauth Konrad
doaj   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

An intelligent system for risk classification of stock investment projects [PDF]

, 2003
The proposed paper demonstrates that a hybrid fuzzy neural network can serve as a risk classifier of stock investment projects. The training algorithm for the regular part of the network is based on bidirectional incremental evolution proving more ...
Kalganova, T, Khan, T, Serguieva, A
core  

BLADE‐ON‐PETIOLE Genes Enable Genetic Bottleneck Mitigation Through Cross‐Species Repurposing of Floral Persistence Traits

Advanced Science, EarlyView.
This study shows that BLADE‐ON‐PETIOLE (BOP) proteins regulate floral abscission and senescence in tomato by interacting with TFAM1 to form transcriptional condensates controlling the ARABIDOPSIS THALIANA HOMEOBOX GENE 1 (ATH1)‐mediated abscission pathway.
Nan Xiao, Qianwen Lyu, Tinghao Zhang, Yupan Zou, Yue Xie, Dandan Yang, Cao Xu, Xiaozhen Huang   +7 more
wiley   +1 more source

Corrigendum: Dynamic nature of SecA and Its associated proteins in Escherichia coli

Frontiers in Microbiology, 2021
Shun Adachi, Yasuhiro Murakawa, Sota Hiraga   +2 more
doaj   +1 more source

Escherichia coli CrfC Protein, a Nucleoid Partition Factor, Localizes to Nucleoid Poles via the Activities of Specific Nucleoid-Associated Proteins

Frontiers in Microbiology, 2019
The Escherichia coli CrfC protein is an important regulator of nucleoid positioning and equipartition. Previously we revealed that CrfC homo-oligomers bind the clamp, a DNA-binding subunit of the DNA polymerase III holoenzyme, promoting colocalization of
Saki Taniguchi, Kazutoshi Kasho, Shogo Ozaki, Tsutomu Katayama   +3 more
doaj   +1 more source

Gemella morbillorum Promotes Colorectal Carcinogenesis: LPBDCP‐Mediated Invasion Activates Ras Signaling and Destabilizes p53

Advanced Science, EarlyView.
ABSTRACT Gut microbiota dysbiosis promotes colorectal cancer (CRC) tumorigenesis. A global fecal metagenomic analysis identified Gemella morbillorum as a key contributor to the CRC‐associated microbiota. Fluorescence in situ hybridization revealed that Gemella morbillorum is enriched in CRC tumor tissues compared to adjacent normal tissues.
Zhen Wang, Jia Zhang, Haojie Lu, Jingjing Ni, Shuaishuai Yang, Yuting Shi, Shuo Zhang, Pei Zhang, Li Liu   +8 more
wiley   +1 more source

Topoisomerase IV is required for partitioning of circular chromosomes but not linear chromosomes in Streptomyces

Nucleic Acids Research, 2013
Abstract Filamentous bacteria of the genus Streptomyces possess linear chromosomes and linear plasmids. Theoretically, linear replicons may not need a decatenase for post-replicational separation of daughter molecules. Yet, Streptomyces contain parC and parE that encode the subunits for the decatenase topoisomerase IV.
Huang, Tzu-Wen, Hsu, Chin-Chen, Yang, Han-Yu, Chen, Carton W.   +3 more
openaire   +2 more sources

Random Forest as a tumour genetic marker extractor [PDF]

, 2019
Identifying tumour genetic markers is an essential task for biomedicine. In this thesis, we analyse a dataset of chromosomal rearrangements of cancer samples and present a methodology for extracting genetic markers from this dataset by using a Random ...
Pérez Arnal, Raquel Leandra
core   +1 more source