Results 101 to 110 of about 455,442 (295)

X Chromosome Pericentric Inversion: Report of a Case with 46,X,inv(X)(p11.2q26) and a Mini-Review of the Literature

Gazi Medical Journal
Pericentric inversions arise from double breaks on opposite arms of the chromosome, followed by 180° rotation and reintegration of the broken segment. Carriers of an inversion are mostly phenotypically healthy.
Emine Göktaş, Betül Okur Altındaş, Ayşe Gül Zamani, Mahmut Selman Yıldırım   +3 more
doaj   +1 more source

Chromosome breakpoint distribution of damage induced in peripheral blood lymphocytes by densely ionising radiation [PDF]

, 2006
Purpose: To assess the chromosomal breakpoint distribution in human peripheral blood lymphocytes (PBL) after exposure to a low dose of high linear energy transfer (LET) α-particles using the technique of multiplex fluorescence in situ hybridisation (m ...
Anderson, RM, Papworth, DG, Sumption, ND, Goodhead, DT   +3 more
core   +1 more source

Does a subset of mature T‐cell leukemias with features akin to T‐cell prolymphocytic leukemia but lacking rearrangement of the TCL1 represent peripheral T‐cell lymphoma, NOS in a leukemic phase?

eJHaem
In the current WHO classification, a T‐cell prolymphocytic leukemia (T‐PLL) diagnosis requires lymphocytosis of >5 × 109/L, evidence of monoclonality, and TCL1A or MTCP1 rearrangement. However, the 2019 consensus document suggested that in the absence of
David C. Gajzer, Xueyan Chen, Daniel E. Sabath, Christina Poh, Kikkeri N. Naresh   +4 more
doaj   +1 more source

Structure of the germline genome of Tetrahymena thermophila and relationship to the massively rearranged somatic genome

eLife, 2016
The germline genome of the binucleated ciliate Tetrahymena thermophila undergoes programmed chromosome breakage and massive DNA elimination to generate the somatic genome.
Eileen P Hamilton, Aurélie Kapusta, Piroska E Huvos, Shelby L Bidwell, Nikhat Zafar, Haibao Tang, Michalis Hadjithomas, Vivek Krishnakumar, Jonathan H Badger, Elisabet V Caler, Carsten Russ, Qiandong Zeng, Lin Fan, Joshua Z Levin, Terrance Shea, Sarah K Young, Ryan Hegarty, Riza Daza, Sharvari Gujja, Jennifer R Wortman, Bruce W Birren, Chad Nusbaum, Jainy Thomas, Clayton M Carey, Ellen J Pritham, Cédric Feschotte, Tomoko Noto, Kazufumi Mochizuki, Romeo Papazyan, Sean D Taverna, Paul H Dear, Donna M Cassidy-Hanley, Jie Xiong, Wei Miao, Eduardo Orias, Robert S Coyne   +35 more
doaj   +1 more source

NUT Midline Carcinoma: A Rare Solid Tumour Characterized by Chromosome Rearrangement. [PDF]

Evid Based Complement Alternat Med, 2022
Zhang H, Kong W, Liang W.
europepmc   +1 more source

Male reproductive system in stenopodidean shrimps: Unveiling basal reproductive traits in shrimp‐like Pleocyemata (Stenopodidae and Spongicolidae)

The Anatomical Record, EarlyView.
Abstract Stenopodidea represents one of the basal lineages within Pleocyemata, yet the male reproductive system (MRS) of this group remains poorly understood, with limited information available regarding its morphology and function. This study provides the first detailed description of the MRS in four stenopodidean shrimp species from two families ...
Caio Santos Nogueira, Lucas Rezende Penido Paschoal, Fernando José Zara   +2 more
wiley   +1 more source

Global chromosome rearrangement induced by CRISPR-Cas9 reshapes the genome and transcriptome of human cells. [PDF]

Nucleic Acids Res, 2022
Liu Y, Ma G, Gao Z, Li J, Wang J, Zhu X, Ma R, Yang J, Zhou Y, Hu K, Zhang Y, Guo Y.   +11 more
europepmc   +1 more source

Comparative Genomic Hybridization of Human Malignant Gliomas Reveals Multiple Amplification Sites and Nonrandom Chromosomal Gains and Losses [PDF]

, 1994
Nine human malignant gliomas (2 astrocytomas grade III and 7 glioblastomas) were analyzed using comparative genomic hybridization (CGH). In addition to the amplification of the EGFR gene at 7p12 in 4 of 9 cases, six new amplification sites were mapped to
Vogel, S., Ried, Thomas, Thiel, G., Manoir, Stanislas du, Meffert, M. C., Speicher, Michael R., Cremer, Thomas, Donis-Keller, Helen, Nürnberg, P., Lozonova, T., Jauch, Anna, Schröck, Evelin, Witkowski, R., Jänisch, W.   +13 more
core   +1 more source

Genetic Diversity, Adaptation, Wild Introgression, and Coat Color Mutation of Golden Yak

Animal Research and One Health, EarlyView.
Genetic diversity, adaptation, wild introgression, and coat color mutation of golden yak from two populations on the Qinghai‐Xizang Plateau. ABSTRACT The golden yak lives on the Qinghai‐Xizang Plateau with a golden coat and adapts to high altitudes and strong ultraviolet environment. The golden coat is a prominent phenotype in many domesticated species,
Huixuan Yan, Jialei Chen, Chuzhao Lei, Fengwei Zhang, Shunzhong He, Weiru Song, Hongyan Ma, Shuling Li, Guomei Li, Laba Yongcuo, Jianlin Han, Johannes A. Lenstra, Qiang Zhang, Rende Song, Basang Wangdui, Ningbo Chen   +15 more
wiley   +1 more source

An Incidental Detection of a Cryptic Complex Chromosome Rearrangement Found During NGS Based PGT-SR: A Case Report. [PDF]

J Reprod Infertil, 2022
Özer L, Aktuna S, Unsal E, Baltaci A, Baltaci V.   +4 more
europepmc   +1 more source