Results 251 to 260 of about 234,024 (306)

The DNA helicase RTEL1 is involved in the repair of replicative DNA damage independently of the alternative end joining and the DNA-protein cross-link repair pathways in Arabidopsis. [PDF]

Plant J
Goldkuhle L, Lechner L, Capdeville N, Dorn A, Puchta H.   +4 more
europepmc   +1 more source

Loss of Pol32, a subunit of DNA polymerases δ and ζ, leads to different patterns of genome stability than direct impairment of these individual polymerases. [PDF]

mBio
Qi L, Li K-J, Tang X-X, Tian L-Y, Wang Y-K, He M, Zhang K, Petes TD, Zheng D-Q.   +8 more
europepmc   +1 more source

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Regulation of Chromosome Replication

Annual Review of Biochemistry, 2000
▪ Abstract  The initiation of DNA replication in eukaryotic cells is tightly controlled to ensure that the genome is faithfully duplicated once each cell cycle. Genetic and biochemical studies in several model systems indicate that initiation is mediated by a common set of proteins, present in all eukaryotic species, and that the activities of these ...
T J, Kelly, G W, Brown
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Replication of the bacterial chromosome

Proceedings of the Royal Society of London. Series B. Biological Sciences, 1966
Abstract In this paper I shall confine myself to only one aspect of chromosome replication in bacteria: its control and co-ordination with growth and cell division. The nature of the problem to be considered is made clear by two features of chromosome replication in Escherichia coli, First, under conditions of rapid growth, involving ...
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Replication of adenovirus mini-chromosomes

Journal of Molecular Biology, 1984
We have isolated adenovirus origins of DNA replication from both the right and left ends of the genome, which are functional on linear autonomously replicating mini-chromosomes. The mini-chromosomes contain two cloned inverted adenovirus termini and require non-defective adenovirus as a helper.
R T, Hay, N D, Stow, I M, McDougall
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Bacterial chromosome origins of replication

Current Opinion in Genetics & Development, 1993
Bacteria regulate chromosomal replication from one specific origin. We compare the regulatory requirements, DNA structures, and biochemical properties of the prototypic Escherichia coli origin with those of evolutionarily distant Bacillus subtilis and Caulobacter crescentus origins.
G T, Marczynski, L, Shapiro
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Replication of Yeast Chromosomal DNA

Nature, 1974
THE study of replication in higher eukaryotes has been hampered by the large size of the DNA molecules in their chromosomes. The yeast Saccharomyces cerevisiae is a eukaryote with very little DNA per haploid nucleus (9 × 109 daltons)1. This has facilitated measurement of intact yeast chromosomal DNA by sedimentation velocity2 and electron microscopy3 ...
C S, Newlon, T D, Petes, L M, Hereford, W L, Fangman   +3 more
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A fractal model of chromosomes and chromosomal DNA replication

Journal of Theoretical Biology, 1989
With the aim of clarifying topological problems involved in the process of chromosomal DNA replication, a fractal model of chromosomes was built based on the assumption that a part of a chromosome, e.g. a radial loop, is similar in shape to a whole chromosome and each radial loop represents structures in the lower-order organization (an assumption of ...
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Replication in Polytene Chromosomes

1972
Replication of polytene chromosomes has been reviewed frequently in the last two decades, either as a facet of chromosome replication in general or in treatments restricted to polytene nuclei. The reader is referred especially to the following for further discussion and bibliographic references: Beermann (1962), Pelling (1969), Taylor (1969), Prescott (
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The haloarchaeal chromosome replication machinery

Biochemical Society Transactions, 2009
The powerful combination of genetic and biochemical analysis has provided many key insights into the structure and function of the chromosomal DNA replication machineries of bacterial and eukaryotic cells. In contrast, in the archaea, biochemical studies have dominated, mainly due to the absence of efficient genetic systems for these organisms.
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