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Initiation of Chromosomal Replication
2014The complex process of bacterial chromosomal replication can be divided into several stages: initiation, priming of chain starts, chain elongation, and termination. Since much of what is known about the initiation of bacterial chromosomal replication comes from studies of Escherichia coli, this chapter concentrates on initiation in that organism.
Johanna Eltz Camara, Elliott Crooke
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Replication of DNA in Eukaryotic Chromosomes
1987Studies of DNA replication in chromosomes first clearly revealed the compartments of the cell cycle and provided a means for measuring the parameters of the S-phase in the cell cycle. Radioisotopic labeling, especially with [3H]-thymidine, provided a specific label easily detected by autoradiography, as well as by liquid scintillation counting for ...
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Chromosome Replication and Segregation
2014This chapter reviews our current understanding of bacterial DNA replication and chromosome partitioning in Bacillus subtilis and makes comparisons to Escherichia coli and other organisms where appropriate. Bacterial chromosome replication initiates once per cell division cycle in response to a signal that is tightly coupled to cell mass.
Katherine P. Lemon +3 more
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EUKARYOTIC CHROMOSOME REPLICATION
Annual Review of Genetics, 1975H J, Edenberg, J A, Huberman
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The Replication of Yeast Chromosomes
1996Eukaryotic chromosomes consist of linear DNA molecules that are complexed with proteins to form chromatin. Early analysis of replicating chromosomal DNA by fiber autoradiography revealed that replication initiates at multiple sites along each DNA molecule and that replication forks move bidirectionally away from the initiation sites (Huberman and Riggs
J. F. Theis, C. S. Newlon
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Replication: Organization and Replication of the Eukaryotic Chromosome
1977There is increasing evidence that the variation in nuclear DNA content between species is caused predominantly by the variation of the amount of repetitive DNA (FLAVELL et al.; NAGL, 4, 6). NARAYAN and REES studied nine species of Lathyrus, where the 2C DNA content ranges from 12.45 pg to 20.27 pg.
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Termination of Chromosome Replication
2014This chapter discusses the components of the terminus-region replication fork-arrest system, their organization and structural features, and their functioning during termination of a round of vegetative replication in Bacillus subtilis. Progress in characterizing and understanding the components and features associated with termination of replication ...
I. G. Duggin, R. G. Wake
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Origins of Chromosome Replication
1998The first obligatory step for replication of duplex DNA is strand separation. Duplex melting (unwinding) leading to initiation of bacterial chromosome replication normally occurs at a fixed site on the chromosome termed oriC. This local duplex unwinding is effected by specific binding of an initiator, DnaA protein encoded by the dnaA gene, to 9-bp ...
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Bacterial chromosomes and their replication
This chapter reviews the current knowledge on the organization and replication of bacterial genomes with a special emphasis on the initiation of DNA replication. Most bacteria contain one chromosome, however a few species, like the human pathogen Vibrio cholerae, carry a secondary chromosome.Frimodt-Møller, Jakob +3 more
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Replication origins in the eucaryotic chromosome
Cell, 1981R A, Laskey, R M, Harland
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