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The Replication of Yeast Chromosomes
1996Eukaryotic chromosomes consist of linear DNA molecules that are complexed with proteins to form chromatin. Early analysis of replicating chromosomal DNA by fiber autoradiography revealed that replication initiates at multiple sites along each DNA molecule and that replication forks move bidirectionally away from the initiation sites (Huberman and Riggs
J. F. Theis, C. S. Newlon
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Replication origins in the eucaryotic chromosome
Cell, 1981R A, Laskey, R M, Harland
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Bacterial chromosomes and their replication
This chapter reviews the current knowledge on the organization and replication of bacterial genomes with a special emphasis on the initiation of DNA replication. Most bacteria contain one chromosome, however a few species, like the human pathogen Vibrio cholerae, carry a secondary chromosome.Frimodt-Møller, Jakob +3 more
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Origins of Chromosome Replication
1998The first obligatory step for replication of duplex DNA is strand separation. Duplex melting (unwinding) leading to initiation of bacterial chromosome replication normally occurs at a fixed site on the chromosome termed oriC. This local duplex unwinding is effected by specific binding of an initiator, DnaA protein encoded by the dnaA gene, to 9-bp ...
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Replication stress impairs chromosome segregation and preimplantation development in human embryos
Cell, 2022exaly
Initiation of the Streptomyces chromosome replication
Antonie van Leeuwenhoek, 2000J, Zakrzewska-Czerwińska +4 more
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