Results 51 to 60 of about 693,747 (160)

A rewiring of DNA replication mediated by MRE11 exonuclease underlies primed-to-naive cell de-differentiation

Cell Reports
Summary: Mouse embryonic stem cells (mESCs) in the primed pluripotency state, which resembles the post-implantation epiblast, can be de-differentiated in culture to a naive state that resembles the pre-implantation inner cell mass.
Patricia Ubieto-Capella, Pilar Ximénez-Embún, Daniel Giménez-Llorente, Ana Losada, Javier Muñoz, Juan Méndez   +5 more
doaj   +1 more source

Two different cell-cycle processes determine the timing of cell division in Escherichia coli

eLife, 2021
Cells must control the cell cycle to ensure that key processes are brought to completion. In Escherichia coli, it is controversial whether cell division is tied to chromosome replication or to a replication-independent inter-division process.
Alexandra Colin, Gabriele Micali, Louis Faure, Marco Cosentino Lagomarsino, Sven van Teeffelen   +4 more
doaj   +1 more source

Identification of candidate genes for dyslexia susceptibility on chromosome 18 [PDF]

, 2010
Background: Six independent studies have identified linkage to chromosome 18 for developmental dyslexia or general reading ability. Until now, no candidate genes have been identified to explain this linkage.
Olson, R K, Pennington Bruce F., Anthony P. Monaco, Pennington, B F, Scerri, TS, Alex J. Richardson, Smith, SD, Talcott, J, Richard K. Olson, Alex J Richardson, MacPhie, I L, Joel Talcott, Bruce F Pennington, Stein, J, Monaco, AP, Morris Andrew, Pennington, BF, Olson Richard K., Silvia Paracchini, Macphie, IL, DeFries, J C, Anthony P Monaco, Thomas S Scerri, Smith, Shelley D., Richardson, Alex J., Olson, RK, I Laurence MacPhie, Stein, John, Shelley D. Smith, Pennington, Bruce F., Monaco, Anthony P., Defries, JC, Paracchini, Silvia, John Stein, Stein, John F., Scerri Thomas S., MacPhie I. Laurence, Talcott, Joel B., I. Laurence MacPhie, Richardson, Alexandra, Monaco, Anthony, Andrew Morris, John C. DeFries, Talcott Joel, Morris, Andrew, Smith, S D, Smith Shelley D., Talcott, Joel, Bruce F. Pennington, Monaco Anthony P., Olson, Richard K., MacPhie, I. Laurence, Morris, A, Richardson, AJ, Paracchini, S, DeFries, John C., DeFries John C., Shelley D Smith, Stein John, John C DeFries, Monaco, A P, Richard K Olson, Paracchini Silvia, Thomas S. Scerri, Scerri, Thomas S., Scerri, T S   +65 more
core   +1 more source

Localization of an accessory helicase at the replisome is critical in sustaining efficient genome duplication [PDF]

, 2010
© The Author(s) 2010. Published by Oxford University PressGenome duplication requires accessory helicases to displace proteins ahead of advancing replication forks.
Lloyd, RG, McGlynn, P, Hazel Bell, Robert G. Lloyd, John Atkinson, Peter McGlynn, Atkinson, J, Bell, H, Christian J. Rudolph, Gupta, MK, Rudolph, CJ, Milind K. Gupta   +11 more
core   +1 more source

Choreography of the Mycobacterium Replication Machinery during the Cell Cycle

mBio, 2015
It has recently been demonstrated that bacterial chromosomes are highly organized, with specific positioning of the replication initiation region. Moreover, the positioning of the replication machinery (replisome) has been shown to be variable and ...
Damian Trojanowski, Katarzyna Ginda, Monika Pióro, Joanna Hołówka, Partycja Skut, Dagmara Jakimowicz, Jolanta Zakrzewska-Czerwińska   +6 more
doaj   +1 more source

Yta7, a chromatin segregase regulated by the cell cycle machinery

Molecular & Cellular Oncology, 2022
We have recently revealed the existence of a cell cycle-regulated chromatin segregase, Yta7 (Yeast Tat-binding Analog 7), involved in chromosome replication. Phosphorylation of Yta7 by S-CDK (S-phase Cyclin-Dependent Kinase) regulates its function. These
Priyanka Bansal, Christoph F. Kurat
doaj   +1 more source

The radial arrangement of the human chromosome 7 in the lymphocyte cell nucleus is associated with chromosomal band gene density [PDF]

, 2008
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ Springer-Verlag 2008.In the nuclei of human lymphocytes, chromosome territories are distributed according to the average gene density of ...
Federico, C, Tosi, S, Cantarella, CD, Saccone, S, Di Mare, P   +4 more
core   +1 more source

Ciz1 cooperates with cyclin-A-CDK2 to activate mammalian DNA replication in vitro [PDF]

, 2010
Initiation of mammalian DNA replication can be reconstituted from isolated G1-phase nuclei and cell extracts, supplemented with cyclin-dependent protein kinases (CDKs).
Sercombe, Heather E, Ainscough, Justin F X, Coverley, Dawn, Copeland, Nikki A   +3 more
core   +4 more sources

Structure and Function of the Campylobacter jejuni Chromosome Replication Origin

Frontiers in Microbiology, 2018
Campylobacter jejuni is the leading bacterial cause of foodborne infections worldwide. However, our understanding of its cell cycle is poor. We identified the probable C.
Pawel Jaworski, Rafal Donczew, Thorsten Mielke, Christoph Weigel, Kerstin Stingl, Anna Zawilak-Pawlik   +5 more
doaj   +1 more source

Crosstalk Regulation Between Bacterial Chromosome Replication and Chromosome Partitioning

Frontiers in Microbiology, 2019
Despite much effort, the bacterial cell cycle has proved difficult to study and understand. Bacteria do not conform to the standard eukaryotic model of sequential cell-cycle phases.
Gregory T. Marczynski, Kenny Petit, Priya Patel   +2 more
doaj   +1 more source