Resolution of Joint Molecules by RuvABC and RecG Following Cleavage of the Escherichia coli Chromosome by EcoKI [PDF]
, 2009 DNA double-strand breaks can be repaired by homologous recombination involving the formation and resolution of Holliday junctions. In Escherichia coli, the RuvABC resolvasome and the RecG branch-migration enzyme have been proposed to act in alternative ...
Okely Ewa +8 more
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Separation of DNA replication from the assembly of break-competent meiotic chromosomes. [PDF]
PLoS Genetics, 2012 The meiotic cell division reduces the chromosome number from diploid to haploid to form gametes for sexual reproduction. Although much progress has been made in understanding meiotic recombination and the two meiotic divisions, the processes leading up ...
Hannah G Blitzblau +3 more
doaj +1 more source
Avoiding chromosome pathology when replication forks collide [PDF]
, 2013 This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2013 Macmillan Publishers Limited.Chromosome duplication normally initiates through the assembly of replication fork complexes at defined ...
Lloyd, RG +3 more
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Chromosome Organization and Replisome Dynamics in
mBio, 2015 Subcellular organization of the bacterial nucleoid and spatiotemporal dynamics of DNA replication and segregation have been studied intensively, but the functional link between these processes remains poorly understood.
Isabella Santi, John D. McKinney
doaj +1 more source
Experimental study on effect of simulated microgravity on structural chromosome instability of human peripheral blood lymphocytes. [PDF]
PLoS ONE, 2014 Experimental study was made by keeping human peripheral blood lymphocytes under simulated microgravity in a Rotary Cell Culture System bioreactor to investigate the changes that occur in the number of chromosomes, the expression rate of chromosome ...
Lijun Wei +6 more
doaj +1 more source
Units of chromosome replication and packing [PDF]
Journal of Cell Science, 1983 ABSTRACT Fusion between mitotic and S-phase cells induces the formation of prematurely condensed chromosomes (PCC) in the interphase partner. Viewed in the light microscope, S-phase PCC derived from the Indian muntjac appear to be fragmented and heterogeneous. In scanning electron micrographs prepared by an osmium impregnation technique,
A M, Mullinger, R T, Johnson
openaire +2 more sources
USF binding sequences from the HS4 insulator element impose early replication timing on a vertebrate replicator [PDF]
, 2012 The nuclear genomes of vertebrates show a highly organized program of DNA replication where GC-rich isochores are replicated early in S-phase, while AT-rich isochores are late replicating.
Chilaka, S. +20 more
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Differential Requirements for MCM Proteins in DNA Replication in Drosophila S2 Cells. [PDF]
, 2007 BACKGROUND: The MCM2-7 proteins are crucial components of the pre replication complex (preRC) in eukaryotes. Since they are significantly more abundant than other preRC components, we were interested in determining whether the entire cellular content was
Reina Hashimoto +30 more
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Chromosome-wide profiles of replication timing and repair.
, 2022 Replication timing profiles are shown for chromosome 1 and 19 until 50 Mb. Profiles are colored by the local ratio of (A) normalized repair rate and (B) Early/Late S phase normalized repair rate of CPD 12 minutes samples. (TIF)
Jinchuan Hu (1909264) +7 more
core +1 more source
Chk1 inhibits replication factory activation but allows dormant origin firing in existing factories [PDF]
, 2010 Replication origins are licensed by loading MCM2-7 hexamers before entry into S phase. However, only similar to 10% of licensed origins are normally used in S phase, with the others remaining dormant.
Blow, J. Julian; id_orcid +4 more
core +1 more source