Avian Lifespan Network Reveals Shared Mechanisms and New Key Players in Animal Longevity
Aging Cell, EarlyView.In this work, we found that birds with similar lifespans exhibit convergent evolution in specific genes, suggesting that shared evolutionary pressures shape the genetic basis of lifespan similarity across species. By investigating protein–protein interactions across genes evolving convergently in long‐ and short‐lived species, we identified a network ...
Mirko Martini +3 more
wiley +1 more source
An Aurora kinase A-BOD1L1-PP2A B56 axis promotes chromosome segregation fidelity. [PDF]
Cell RepKucharski TJ +6 more
europepmc +1 more source
Analysis of chromosome loss and chromosome segregation in cytokinesis-blocked human lymphocytes: non-disjunction is the prevalent mistake in chromosome segregation produced by low dose exposure to ionizing radiation [PDF]
, 2000 Nadia Touil
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Segregating meiotic chromosomes [PDF]
Nature Structural & Molecular Biology, 2013 openaire +2 more sources
A historical perspective on Lionel Penrose: Scientist, geneticist and dedicated opponent of eugenics
Annals of Human Genetics, EarlyView.Abstract The paper explores Lionel Penrose's scientific work. Penrose investigated the causes of mental disorders from clinical and genetic points of view. His investigations on phenylketonuria and Down syndrome helped to demonstrate the heterogenous character of mental disorders, whose causes can range from genetic with high penetrance, to largely ...
Maria Kiladi
wiley +1 more source
Chk2 sustains PLK1 activity in mitosis to ensure proper chromosome segregation. [PDF]
Nat CommunBlack EM +7 more
europepmc +1 more source
CHL1 is a nuclear protein with an essential ATP binding site that exhibits a size-dependent effect on chromosome segregation [PDF]
, 2000 Sandra L Holloway
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Genetic Determinants of the Familial Hypercholesterolaemia Phenotype
Annals of Human Genetics, EarlyView.ABSTRACT Individuals with familial hypercholesterolaemia (FH) have severely elevated plasma concentrations of low‐density lipoprotein cholesterol (LDL‐C) from birth and as a consequence have an elevated morbidity and mortality due to the development of coronary heart disease (CHD).
Steve Eric Humphries, Marta Futema
wiley +1 more source
Fission Yeast Homologs of Human CENP-B Have Redundant Functions Affecting Cell Growth and Chromosome Segregation [PDF]
, 2000 Mary Baum, Louise Clarke
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