Results 261 to 270 of about 187,172 (325)

A disulfidptosis‐related gene signature predicts prognosis and immune‐metabolic landscape in multiple myeloma

open access: yesBritish Journal of Haematology, EarlyView.
Summary Disulfidptosis is a newly recognized cell death induced by disulphide stress under glucose deprivation. However, its clinical implications in multiple myeloma (MM) remain largely unexplored. We identified disulfidptosis‐related genes via co‐expression analysis and developed a risk signature through univariate Cox, least absolute shrinkage and ...
Li Wang   +4 more
wiley   +1 more source

Compartmentalisation in cAMP signalling: A phase separation perspective

open access: yesBritish Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

Segregation of malignant hyperthermia, central core disease and chromosome 19 markers

open access: bronze, 1999
Julie Curran   +10 more
openalex   +1 more source

Reversibility of sex changes in the plant kingdom: more important than we thought?

open access: yesBiological Reviews, EarlyView.
ABSTRACT Compared to animals, plants show a wide range of reproductive strategies with different degrees of sex separation (e.g. dioecy, monoecy, hermaphroditism). While sex expression was previously thought to be genetically determined and fixed in plants, accumulating evidence suggests that sex expression can change reversibly even within one ...
Iris Sammarco   +3 more
wiley   +1 more source

Nuclear destabilisation – a possible genesis of cancer?

open access: yesBiological Reviews, EarlyView.
ABSTRACT This review examines the increasingly prominent role of mechanics within cancer formation and progression. The extremely varied and contradictory genetic landscape of cancer is in stark contrast to the seemingly universal mechanical characteristics of cancer cells and their tumour microenvironment, and mechanics may be a principal unifying ...
Daniel D. Scott   +4 more
wiley   +1 more source

Canonical and Non‐Canonical Functions of Histone H3K4 Methylation Modifiers in Cancer

open access: yesCancer Science, EarlyView.
Histone H3K4‐modifying enzymes regulate gene expression and cellular processes critical to cancer development. Beyond their canonical roles, these enzymes also exhibit non‐catalytic and non‐histone functions, offering new opportunities for therapeutic intervention. ABSTRACT Histone H3K4 modifications are altered in the regulation of gene expression and
Takayuki Hoshii
wiley   +1 more source

RetSat stabilizes mitotic chromosome segregation in pluripotent stem cells. [PDF]

open access: yesCell Mol Life Sci
Cai W   +5 more
europepmc   +1 more source

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