Results 151 to 160 of about 66,240 (247)

Population genomic analyses reveal extensive genomic regions within selective sweeps associated with adaptation and demographic history of a wheat fungal pathogen

New Plant Protection, EarlyView.
Applying population genomics, this study revealed that Pst exhibits slower linkage disequilibrium decay compared to rust fungi with known sexual reproduction, identified extensive hard and soft sweeps linked to Pst adaptation, and demonstrated that crop domestication and breeding programs have significantly influenced pathogen population sizes ...
Yun Xing, Chongjing Xia, Liang Huang, Na Zhao, Hongfu Li, Xingzong Zhang, Age Qiu, Wanqiang Tang, Meinan Wang, Xianming Chen, Bo Liu, Hao Zhang, Li Gao, Wanquan Chen, Taiguo Liu   +14 more
wiley   +1 more source

Carbapenem-Resistant <i>Pseudomonas aeruginosa's</i> Resistome: Pan-Genomic Plasticity, the Impact of Transposable Elements and Jumping Genes. [PDF]

Antibiotics (Basel)
Karampatakis T, Tsergouli K, Behzadi P.
europepmc   +1 more source

Post‐COVID‐19 condition: clinical phenotypes, pathophysiological mechanisms, pathology, and management strategies

The Journal of Pathology, EarlyView.
Abstract Post‐COVID‐19 condition (PCC), also known as long COVID, is a complex multiple organ system condition that can develop and persist for months after acute COVID‐19. PCC encompasses a wide range of symptoms, resulting in heterogeneous clinical manifestations. These manifestations likely arise from diverse underlying pathophysiological mechanisms,
Larissa E Vlaming‐van Eijk, Guolu Tang, Arno R Bourgonje, Wilfred FA den Dunnen, Jan‐Luuk Hillebrands, Harry van Goor   +5 more
wiley   +1 more source

Plasticity of Gene Expression in Spaceflight and Postflight in Relation to Cardiovascular Disease: Mechanisms and Candidate Repurposed Drugs

PROTEOMICS, EarlyView.
ABSTRACT Spaceflight poses unique challenges to human health due to exposure to increased levels of cosmic radiation, microgravity, and associated oxidative stress. These environmental factors can lead to cellular damage, inflammation, and a range of health complications, including cardiovascular problems, immune system impairment, and an increased ...
Marilena M. Bourdakou, Eleni M. Loizidou, George M. Spyrou   +2 more
wiley   +1 more source

Chromosome-level genome assembly of a doubled haploid brook trout (Salvelinus fontinalis). [PDF]

G3 (Bethesda)
Lecomte L, Ferchaud AL, Normandeau E, Mérot C, Langlois-Parisé I, Therrien JC, Bérubé P, Djambazian H, Nawarathna PM, Ragoussis J, Fraser D.   +10 more
europepmc   +1 more source

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

PROTEOMICS, EarlyView.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella, Jens Möller, Christopher Lischer, Julio Vera‐Gonzalez, Jörg Hofmann, Lisa Ott, Andreas Burkovski   +6 more
wiley   +1 more source

Global analysis of the metaplasmidome: ecological drivers and spread of antibiotic resistance genes across ecosystems. [PDF]

Microbiome
Debroas D.
europepmc   +1 more source

The Actin‐Binding Prolyl‐Isomerase Par17 Sustains Its Substrate Selectivity by Interdomain Allostery

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The human peptidyl‐prolyl‐cis/trans isomerases (PPIases), Parvulin 14 and Parvulin 17, accelerate the cis/trans isomerization of Xaa‐Pro moieties within protein sequences. By modulating the respective binding interfaces of their target proteins, they play a crucial role in determining the fate of their substrates within the cell. Although both
Anna Sternberg, Jennifer Lynne Borger, Mathilda Thies, Anja Matena, Mike Blueggel, Bianca E. Kamba, Christine Beuck, Farnusch Kaschani, Markus Kaiser, Peter Bayer   +9 more
wiley   +1 more source

Characterizing Common Factors Affecting Replication Initiation During H₂O₂ Exposure and Genetic Mutation-Induced Oxidative Stress in <i>Escherichia coli</i>. [PDF]

Int J Mol Sci
Qiao J, Zhu W, Du D, Morigen M.
europepmc   +1 more source

FHY3/FAR1 transposable elements generate adaptive genetic variation in the Bassia scoparia genome

Pest Management Science, EarlyView.
FHY3/FAR1 are active transposable elements and are involved with the formation of genomic structural variants that cause glyphosate resistance in Bassia scoparia. Abstract BACKGROUND A nearly complete genome assembly consisting of 14 scaffolds, a total length of 969.6 Mb, and an N50 scaffold length of 99.88 Mb, was generated to better understand how ...
Nathan Hall, Jacob Montgomery, Jinyi Chen, Christopher Saski, Maor Matzrafi, Phil Westra, Todd Gaines, Eric Patterson   +7 more
wiley   +1 more source