Results 201 to 210 of about 66,240 (247)

Comprehensive αβ T‐Cell Receptor Repertoire Analysis Reveals a Unique CD8+ TCR Landscape in DOCK8‐Deficient Patients

Allergy, EarlyView.
T cell receptor repertoire analysis by high‐throughput immune repertoire RNA‐sequencing in the patients with DOCK8 deficiency. Comprehensive comparisons revealed a restricted TCR repertoire diversity in the patients. Additional assessments showed potential auto‐reactive CD8+ T cell clones in the patients.Abbreviations: DOCK8, dedicator of cytokinesis ...
Ceren Bozkurt, Gökhan Cildir, Umran Aba, Rahmi Kutay Erdogan, Nicholas I Warnock I, Chung Hoow Kok, Asena Pinar Sefer, Sule Haskologlu, Sidem Didar Tekeoglu, Gülşah Merve Kılınç, Canberk Ipsir, Tugba Arikoglu, Aylin Kont Ozhan, Saliha Esenboga, Ahmet Özen, Elif Karakoç‐Aydiner, Sevgi Bilgiç Eltan, Çigdem Aydogmus, Candan Islamoglu, Kübra Baskın, Betul Karaatmaca, Ayse Metin, Deniz Çagdaş, Figen Dogu, Aydan Ikinciogullari, Safa Baris, Baran Erman   +26 more
wiley   +1 more source

Kalamari: a representative set of genomes of public health concern. [PDF]

Microbiol Resour Announc
Katz LS, Griswold T, Lindsey RL, Lauer AC, Im MS, Williams G, Halpin JL, Gómez GA, Kucerova Z, Morrison S, Page A, Den Bakker HC, Carleton HA.   +12 more
europepmc   +1 more source

Luteinizing hormone receptor knockout mouse: What has it taught us?

Andrology, EarlyView.
Abstract Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis ...
Ilpo T. Huhtaniemi
wiley   +1 more source

Identification of a novel aminoglycoside nucleotidyltransferase gene in Morganella morganii from farm sewage. [PDF]

BMC Microbiol
Lu J, Wang J, Gao M, Zhou K, Liang J, Song C, He X, Liu C, Feng H, Pan W, Bao Q, Yan C, Huang D.   +12 more
europepmc   +1 more source

Comprehensive diagnostic and therapeutic approach to male factor infertility aimed at natural fertility: A multicentric retrospective cohort study

Andrology, EarlyView.
Abstract Background In infertile couples whose male partner has alterations in semen parameters frequently, a comprehensive andrological approach is lacking and approximately 30–50% are classified as idiopathic infertility. These couples are often directly addressed to assisted reproduction techniques (ARTs).
Giuseppe Grande, Andrea Garolla, Andrea Graziani, Anna Laura Astorri, Maria Vittoria Cammarota, Annamaria Merola, Maria Pia Polidori, Emanuela Lulli, Enrico Busato, Francesco Pesce, Giuseppina Pompa, Alfredo Pontecorvi, Domenico Milardi, Alberto Ferlin   +13 more
wiley   +1 more source

Genome-wide association study and transcriptomic analysis reveal the crucial role of <i>sting1</i> in resistance to visceral white-nodules disease in <i>Larimichthys polyactis</i>. [PDF]

Front Immunol
Zhu J, Liu F, Ye T, Li Q, Liu H, Liu S, Zhang T, Guo D, Zhu J, Lou B.   +9 more
europepmc   +1 more source

Herpes simplex virus‐1 infection alters microtubule‐associated protein Tau splicing and promotes Tau pathology in neural models of Alzheimer's disease

Brain Pathology, EarlyView.
HSV‐1 infection alters MAPT splicing and promotes Tau pathology in neural models of Alzheimer's disease. HSV‐1 infection in brain organoids and neuronal models increase 4R‐MAPT splicing and Tau hyperphosphorylation. HSV‐1 ICP27 is both necessary and sufficient for inducing these changes highlighting the potential role of HSV‐1 in Alzheimer's disease ...
Emmanuel C. Ijezie, Michael J. Miller, Celine Hardy, Ava R. Jarvis, Timothy F. Czajka, Lianna D'Brant, Natasha Rugenstein, Adam Waickman, Eain Murphy, David C. Butler   +9 more
wiley   +1 more source

Investigation of genomic island 2 deciphers the evolution of a genus Brucella. [PDF]

Sci Rep
Banai M.
europepmc   +1 more source

Chromosome-scale whole genome assembly and annotation of the Jamaican field cricket Gryllus assimilis. [PDF]

Sci Data
Ito Y, Sanno R, Ashikari S, Yura K, Asahi T, Ylla G, Kataoka K.   +6 more
europepmc   +1 more source

Non‐canonical nitric oxide signalling and DNA methylation: Inflammation induced epigenetic alterations and potential drug targets

British Journal of Pharmacology, EarlyView.
Abstract DNA methylation controls DNA accessibility to transcription factors and other regulatory proteins, thereby affecting gene expression and hence cellular identity and function. As epigenetic modifications control the transcriptome, epigenetic dysfunction is strongly associated with pathological conditions and ageing.
Christopher H. Switzer
wiley   +1 more source