Results 71 to 80 of about 74,687 (303)

DistAMo: A web-based tool to characterize DNA-motif distribution on bacterial chromosomes

open access: yesFrontiers in Microbiology, 2016
Short DNA motifs are involved in a multitude of functions such as for example chromosome segregation, DNA replication or mismatch repair. Distribution of such motifs is often not random and the specific chromosomal pattern relates to the respective motif
Patrick eSobetzko   +5 more
doaj   +1 more source

Rapid modification of bacterial artificial chromosomes by ET-recombination [PDF]

open access: yes, 1999
We present a method to modify bacterial artificial chromosomes (BACs) resident in their host strain. The method is based on homologous recombination by ET-cloning.
Muyrers J. P. P.   +3 more
core   +1 more source

Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production

open access: yesAdvanced Science, EarlyView.
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du   +4 more
wiley   +1 more source

Where and When Bacterial Chromosome Replication Starts: A Single Cell Perspective

open access: yesFrontiers in Microbiology, 2018
Bacterial chromosomes have a single, unique replication origin (named oriC), from which DNA synthesis starts. This study describes methods of visualizing oriC regions and the chromosome replication in single living bacterial cells in real-time.
Damian Trojanowski   +2 more
doaj   +1 more source

Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean

open access: yesAdvanced Science, EarlyView.
This study identified NAR5, a gene encoding a subtilisin‐like protease, that regulates nitrogenase activity in soybean nodules. Overexpressing NAR5 delayed nodule senescence, enhancing nitrogenase activity, yield, and low‐nitrogen tolerance. The elite haplotype NAR5HapI‐1 linked to superior nitrogenase activity and greater seed weight has been ...
Chao Ma   +11 more
wiley   +1 more source

Linear dicentric chromosomes in bacterial natural isolates reveal common constraints for replicon fusion

open access: yesmBio
Multipartite bacterial genome organization can confer advantages, including coordinated gene regulation and faster genome replication, but is challenging to maintain.
Ram Sanath-Kumar   +7 more
doaj   +1 more source

Analysis of the SOS response of Vibrio and other bacteria with multiple chromosomes

open access: yesBMC Genomics, 2012
Background The SOS response is a well-known regulatory network present in most bacteria and aimed at addressing DNA damage. It has also been linked extensively to stress-induced mutagenesis, virulence and the emergence and dissemination of antibiotic ...
Sanchez-Alberola Neus   +3 more
doaj   +1 more source

Exotic mitotic mechanisms [PDF]

open access: yes, 2012
The emergence of eukaryotes around two billion years ago provided new challenges for the chromosome segregation machineries: the physical separation of multiple large and linear chromosomes from the microtubule-organizing centres by the nuclear envelope.
Drechsler, Hauke, McAinsh, Andrew D.
core   +1 more source

Comparative Oligo‐FISH Mapping Illuminates Chromosomal Evolution Among Rutaceae Species Diverged Over 50 Million Years

open access: yesAdvanced Science, EarlyView.
Oligonucleotide‐based fluorescence in situ hybridization probes were developed in the model citrus species Citrus maxima. These probes were applied to comparative karyotyping across 14 species in the Rutaceae family. This analysis revealed chromosomal evolution in lineages that diverged from Citrus nearly 52 million years ago.
Li He   +9 more
wiley   +1 more source

Editorial for Special Issue “Bacterial Toxin-Antitoxin Systems”

open access: yesMicroorganisms
Toxin antitoxin systems (TAS) are widely distributed in bacterial chromosomes as well as on mobile genetic elements [...]
Muhammad Kamruzzaman
doaj   +1 more source

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