Results 11 to 20 of about 26,122 (221)

Interspecies hybridization as a route of accessory chromosome origin in fungal pathogens [PDF]

mBio
Fungal plant pathogens have dynamic genomic architectures that can contribute to rapid evolution and adaptation to new niches. Zymoseptoria tritici, an important fungal pathogen of wheat, has a compartmentalized and rapidly evolving genome. In the genome
Wagner C. Fagundes, Mareike Möller, Alice Feurtey, Rune Hansen, Janine Haueisen, Fatemeh Salimi, Alireza Alizadeh, Eva H. Stukenbrock   +7 more
doaj   +4 more sources

Recurrent Chromosome Destabilization Through Repeat-Mediated Rearrangements in a Fungal Pathogen [PDF]

Genome Biology and Evolution, 2023
Abstract Genomic instability caused by chromosomal rearrangements has severe consequences for organismal fitness and progression of cancerous cell lines. The triggers of destabilized chromosomes remain poorly understood but likely co-locate with fragile sites. Here, we retrace a runaway chromosomal degeneration process observed in the
Simone Fouché, Ursula Oggenfuss, Bruce A. McDonald, Daniel Croll   +3 more
openaire   +3 more sources

Genetic and Epigenetic Mechanisms Underlying Reversible Adaptive Responses in Fungi [PDF]

Journal of Fungi
The remarkable ecological success of fungi is supported by their capacity for rapid and often reversible molecular responses to fluctuating environments.
Lufeng Dan, Siyin Liu, Zhihao Qiang, Xiaowen Ye, Jinping Zhang   +4 more
doaj   +2 more sources

Dual RNA-Seq Reveals Molecular Interactions Between Alternaria alternata and Cucumis melo During Postharvest Infection [PDF]

Foods
Alternaria alternata causes major postharvest losses in melons. This dual RNA-seq study analyzed transcriptomic dynamics in both A. alternata strain A2022 and melon during infection.
Yujia Bai, Xiangfeng Zheng, Bin Wu, Xiangyue Kong, Liuchun Du   +4 more
doaj   +2 more sources

Three-dimensional genome architecture connects chromatin structure and function in a major wheat pathogen [PDF]

BMC Biology
Background Genome spatial organization plays a fundamental role in biological function across all domains of life. While the principles of nuclear architecture have been well-characterized in animals and plants, their functional relevance in filamentous ...
Ivona Glavincheska, Cecile Lorrain
doaj   +2 more sources

T2T Colletotrichum lini Genomes with Hifiasm: ONT R9 and R10 Read Processing and Assembly Guidelines for Fungi [PDF]

Journal of Fungi
The assembly of telomere-to-telomere (T2T) genomes is essential for understanding genomic architecture, especially in fungal pathogens with complex karyotypes, such as Colletotrichum lini, causing flax anthracnose disease.
Elizaveta A. Ivankina, Ekaterina M. Dvorianinova, Alexander A. Arkhipov, Antoniy M. Kaplun, Tatiana A. Rozhmina, Ludmila P. Kudryavtseva, Nikolai M. Barsukov, Olesya D. Moskalenko, Fedor D. Kostromskoy, Kirill A. Klimov, Andrei A. Artamonov, Elena V. Borkhert, Daiana A. Krupskaya, Elena N. Pushkova, Nataliya V. Melnikova, Alexey A. Dmitriev   +15 more
doaj   +2 more sources

Fungal artificial chromosomes for mining of the fungal secondary metabolome [PDF]

BMC Genomics, 2015
With thousands of fungal genomes being sequenced, each genome containing up to 70 secondary metabolite (SM) clusters 30-80 kb in size, breakthrough techniques are needed to characterize this SM wealth.Here we describe a novel system-level methodology for unbiased cloning of intact large SM clusters from a single fungal genome for one-step ...
Bok, Jin Woo, Ye, Rosa, Clevenger, Kenneth D, Mead, David, Wagner, Megan, Krerowicz, Amanda, Albright, Jessica C, Goering, Anthony W, Thomas, Paul M, Kelleher, Neil L, Keller, Nancy P, Wu, Chengcang C   +11 more
openaire   +2 more sources

Frequent horizontal chromosome transfer between asexual fungal insect pathogens

Proceedings of the National Academy of Sciences, 2023
Abstract Entire chromosomes are typically only transmitted vertically from one generation to the next. The horizontal transfer of such chromosomes has long been considered improbable, yet gained recent support in several pathogenic fungi where it may affect the fitness or host specificity.
Michael Habig, Anna V. Grasse, Judith Müller, Eva H. Stukenbrock, Hanna Leitner, Sylvia Cremer   +5 more
openaire   +3 more sources

3D models of fungal chromosomes to enhance visual integration of omics data

NAR Genomics and Bioinformatics, 2023
Abstract The functions of eukaryotic chromosomes and their spatial architecture in the nucleus are reciprocally dependent. Hi-C experiments are routinely used to study chromosome 3D organization by probing chromatin interactions. Standard representation of the data has relied on contact maps that show the frequency of interactions ...
Thibault Poinsignon, Mélina Gallopin, Pierre Grognet, Fabienne Malagnac, Gaëlle Lelandais, Pierre Poulain   +5 more
openaire   +2 more sources

The genome organization of Neurospora crassa at high resolution uncovers principles of fungal chromosome topology [PDF]

G3, 2022
Abstract The eukaryotic genome must be precisely organized for its proper function, as genome topology impacts transcriptional regulation, cell division, replication, and repair, among other essential processes. Disruptions to human genome topology can lead to diseases, including cancer. The advent of chromosome conformation capture with
Sara Rodriguez, Ashley Ward, Andrew T Reckard, Yulia Shtanko, Clayton Hull-Crew, Andrew D Klocko   +5 more
openaire   +3 more sources