Results 161 to 170 of about 248,131 (206)

Before hormones: early sex-specific mechanisms shaping nervous system development, function, and postnatal disease susceptibility. [PDF]

Front Behav Neurosci
Tsiarli MA, Larschan EN.
europepmc   +1 more source

A Novel tRNA Half mt‐5’‐tiRNA‐Tyr Promotes Colorectal Cancer Proliferation via Inducing HARS2 Succinylation

Advanced Science, EarlyView.
A mitochondria‐derived tRNA half, mt‐5’‐tiRNA‐Tyr, is upregulated in colorectal cancer tissues and plasma and promotes tumor proliferation. It binds HARS2 and promotes CPT1A‐associated HARS2 K91 succinylation, disrupts HARS2–mt‐tRNA‐His association, impairs mitochondrial translation, enhances succinate‐linked metabolic reprogramming, and shows promise ...
Xinliang Gu, Danping Zhu, Xinwei Liu, Shangshang Hu, Xincheng Yang, Junjie Nie, Tao Xu, Yuqin Pan, Mu Xu, Huiling Sun, Shukui Wang   +10 more
wiley   +1 more source

ChromoMapperWeb: evaluate genome alignments and track assembly steps within an interactive graphic environment. [PDF]

Nucleic Acids Res
Toscano E, Cimmino E, Boccia A, Sepe L, Paolella G.   +4 more
europepmc   +1 more source

TED1 Promotes the Assembly of SCFD3‐D14‐D53 to Reinforce Strigolactone Signaling in Rice

Advanced Science, EarlyView.
This study identifies TED1 as a positive regulator of strigolactones (SL) signaling in rice. The ted1 mutants display dwarfism and increased tillering with significantly reduced SLs sensitivity. Through its longer C‐terminal region, TED1 interacts with D53 and D14 to promote the assembly of SCFD3‐D14‐D53, thereby facilitating the efficient ...
Sheng Luo, Chuanyin Wu, Miao Feng, Wenfan Luo, Rong Miao, Jinsheng Qian, Fan Wang, Chunlei Zhou, Bojuan Liu, Jiale Shao, Ziqi Xun, Yehui Xiong, Zhichao Zhao, Cailin Lei, Shanshan Zhu, Yulong Ren, Xin Wang, Xiuping Guo, Haiyang Wang, Zichao Li, Zhijun Cheng, Qibing Lin, Jianmin Wan   +22 more
wiley   +1 more source

A complete genome for the common marmoset. [PDF]

Cell
Hebbar P, Potapova T, Loucks H, Ray K, Rodrigues MF, Ryabov F, Malukiewicz J, Yoo D, Gomes de Lima L, Haber A, Kumar S, Banerjee S, Borchers M, Garcia GH, Gardner J, Hachem S, Heath HD, Ha SK, Mastoras M, McNulty B, Menendez J, Munson KM, Pal K, Park J, Plösch S, Roos C, Seligmann WE, Shepelev V, Spruce C, Violich I, Walter L, Makova KD, Thathiah A, Sukoff Rizzo SJ, Silva AC, Carter GW, Miga KH, Eichler EE, Conrad DF, Gerton JL, Alexandrov IA, Paten B.   +41 more
europepmc   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

Advanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan, Fuming Cao, Junqiang Mao, Pengbin Yin, Licheng Zhang, Jianjun Wang, Peifu Tang   +6 more
wiley   +1 more source

Chromosome-Scale Assembly of Novel <i>Caenorhabditis sp. 61</i> (strain JU4110). [PDF]

MicroPubl Biol
Lad P, McCauley MA, Eggers VK, Fierst JL, Willicott K.   +4 more
europepmc   +1 more source

The Landscape of Long Non‐Coding RNAs Provides Insights Into the Domestication and Improvement of Pear Fruit

Advanced Science, EarlyView.
This study reveals that long non‐coding RNAs represent important regulatory components underlying pear domestication and improvement. Integrative multi‐omics analyses identify selected lncRNAs associated with fruit traits, while functional validation uncovers a lignin‐related lncRNA, lncRNA‐pys, that promotes lignin accumulation.
Bobo Song, Peilin Han, Jiaming Li, Xiaolong Li, Xiang Zhang, Jing Fan, Dongliang Liu, Jianfa Cai, Lingchao Zhang, Jun Wu   +9 more
wiley   +1 more source

Haplotype-resolved DiMeLo-seq maps centromeric chromatin in a complete diploid human genome. [PDF]

Cell Genom
Xu Y, Loucks H, Menendez J, Ryabov F, Lucas JK, Cechova M, Morina L, Xu E, Dubocanin D, Chittenden C, Asri M, Violich I, Ortiz C, Gardner JMV, Hillaker T, O'Rourke S, McNulty B, Potapova TA, Mitchell MW, Schwartz JP, Straight AF, Gerton JL, Timp W, Alexandrov IA, Altemose N, Miga KH.   +25 more
europepmc   +1 more source

Polymer Concepts in Cellular Function

Advanced Science, EarlyView.
Miao Yu, Shikha Dhiman, Dorothee Dormann, Frauke Gräter, Katja Luck, Friederike Schmid, Andreas Walther, Edward A. Lemke   +7 more
wiley   +1 more source