Results 41 to 50 of about 419,615 (160)

Tandemly repeated DNA families in the mouse genome

open access: yesBMC Genomics, 2011
Background Functional and morphological studies of tandem DNA repeats, that combine high portion of most genomes, are mostly limited due to the incomplete characterization of these genome elements.
Gavrilova Ekaterina V   +4 more
doaj   +1 more source

Correlation between DNase I hypersensitive site distribution and gene expression in HeLa S3 cells. [PDF]

open access: yesPLoS ONE, 2012
Mapping DNase I hypersensitive sites (DHSs) within nuclear chromatin is a traditional and powerful method of identifying genetic regulatory elements. DHSs have been mapped by capturing the ends of long DNase I-cut fragments (>100,000 bp), or 100-1200 bp ...
Ya-Mei Wang   +5 more
doaj   +1 more source

Using Nanopore Sequencing to Obtain Complete Bacterial Genomes from Saliva Samples

open access: yesmSystems, 2022
Obtaining complete, high-quality reference genomes is essential to the study of any organism. Recent advances in nanopore sequencing, as well as genome assembly and analysis methods, have made it possible to obtain complete bacterial genomes from ...
Jonathon L. Baker
doaj   +1 more source

Genomics of an ancient sex chromosome in Tilapia. W633 [PDF]

open access: yes, 2012
We have developed important genomic tools and methods of comparative genomics in the Nile tilapia, Oreochromis niloticus. The physical comparative map generated with BACs allowed us to calculate that there were about one rearrangement of intra ...
Baroiller, Jean-François   +7 more
core  

Multicolor fluorescence in situ hybridization on metaphase chromosomes and interphase Halo-preparations using cosmid and YAC clones for the simultaneous high resolution mapping of deletions in the dystrophin gene [PDF]

open access: yes, 1994
We report on multicolor fluorescence in situ hybridization protocols for the simultaneous visualization of deletion-prone regions for carrier detection of Duchenne/ Becker (DMD/BMD) muscular dystrophy.
Blonden, Lau   +6 more
core   +1 more source

Insertion/deletion polymorphisms are convenient and reliable markers to assess chromosomal instability in human tumors

open access: yesThe International Journal of Biological Markers, 2012
Chromosomal instability (CIN) is frequently associated with a poor outcome in human carcinomas. The genomes of the main human malignancies are well defined as hundreds of tumors have been characterized by arrays.
Agnès Marchio   +4 more
doaj   +1 more source

Additional haplogroups of Toxoplasma gondii out of Africa: population structure and mouse-virulence of strains from Gabon. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2010
BACKGROUND: Toxoplasma gondii is found worldwide, but distribution of its genotypes as well as clinical expression of human toxoplasmosis varies across the continents.
Aurélien Mercier   +8 more
doaj   +1 more source

Nucleotide Frequencies in Human Genome and Fibonacci Numbers [PDF]

open access: yes, 2006
This work presents a mathematical model that establishes an interesting connection between nucleotide frequencies in human single-stranded DNA and the famous Fibonacci's numbers. The model relies on two assumptions.
A. Dress   +14 more
core   +2 more sources

Genetic Stratigraphy of Key Demographic Events in Arabia [PDF]

open access: yes, 2015
The issue of admixture in human populations is normally addressed by genome-wide (GW) studies, and several approaches have been developed to date admixture events [1,2,3,4,5].
Alshamali, Farida   +12 more
core   +3 more sources

An insight into the phylogenetic history of HOX linked gene families in vertebrates

open access: yesBMC Evolutionary Biology, 2007
Background The human chromosomes 2q, 7, 12q and 17q show extensive intra-genomic homology, containing duplicate, triplicate and quadruplicate paralogous regions centered on the HOX gene clusters.
Grzeschik Karl-Heinz, Abbasi Amir
doaj   +1 more source

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