Results 61 to 70 of about 245,879 (248)

Insertion/deletion polymorphisms are convenient and reliable markers to assess chromosomal instability in human tumors

open access: yesThe International Journal of Biological Markers, 2012
Chromosomal instability (CIN) is frequently associated with a poor outcome in human carcinomas. The genomes of the main human malignancies are well defined as hundreds of tumors have been characterized by arrays.
Agnès Marchio   +4 more
doaj   +1 more source

Additional haplogroups of Toxoplasma gondii out of Africa: population structure and mouse-virulence of strains from Gabon. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2010
BACKGROUND: Toxoplasma gondii is found worldwide, but distribution of its genotypes as well as clinical expression of human toxoplasmosis varies across the continents.
Aurélien Mercier   +8 more
doaj   +1 more source

Evolutionary strata on the X chromosomes of the dioecious plant Silene latifolia: Evidence from new sex-linked genes [PDF]

open access: yes, 2007
Despite its recent evolutionary origin, the sex chromosome system of the plant Silene latifolia shows signs of progressive suppression of recombination having created evolutionary strata of different X-Y divergence on sex chromosomes. However, even after
Bergero, Roberta   +3 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization using recombinant DNA libraries [PDF]

open access: yes, 1988
A method of in situ hybridization for visualizing individual human chromosomes from pter to qter, both in metaphase spreads and interphase nuclei, is reported.
Cremer, Thomas   +4 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

An insight into the phylogenetic history of HOX linked gene families in vertebrates

open access: yesBMC Evolutionary Biology, 2007
Background The human chromosomes 2q, 7, 12q and 17q show extensive intra-genomic homology, containing duplicate, triplicate and quadruplicate paralogous regions centered on the HOX gene clusters.
Grzeschik Karl-Heinz, Abbasi Amir
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Cytogenetic analysis on Herichthys minckleyi (Perciformes, Cichlidae) from Cuatrociénegas, Coahuila, México

open access: yesThe European Zoological Journal
The purpose of this work was to use standard Giemsa staining and several chromosome-banding procedures to define the karyotype of Herichthys minckleyi (Perciformes, Cichlidae) from Cuatrociénegas, Coahuila, Mexico.
R. E. Mendoza-Alfaro   +4 more
doaj   +1 more source

Identifying Candidate Genes for Enhancing Grain Zn Concentration in Wheat

open access: yesFrontiers in Plant Science, 2018
Wheat (Triticum aestivum L.) is one of the major staple food crops worldwide. Despite efforts in improving wheat quality, micronutrient levels are still below the optimal range for human nutrition.
Dalia Z. Alomari   +8 more
doaj   +1 more source

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