An interactive e-learning resource to explore Human Chromosomes and the consequences of changes in chromosome number to health and development.
Richard Flint
core
Dosage compensation in birds [PDF]
The Z and W sex chromosomes of birds have evolved independently from the mammalian X and Y chromosomes [1]. Unlike mammals, female birds are heterogametic (ZW), while males are homogametic (ZZ).
Bird, Adrian P +14 more
core +1 more source
Metaphase and Interphase Cytogenetics with Alu-PCR-amplified Yeast Artificial Chromosome Clones Containing the BCR Gene and the Protooncogenes c-raf-1, c-fms, and c-erbB-21 [PDF]
A human yeast artificial chromosome (YAC) library was screened by polymerase chain reaction with oligonucleotide primers defined for DNA sequences of the BCR gene and the protooncogenes c-raf-1, c-fms, and c-erB-2.
Olson, Maynard V. +17 more
core +1 more source
Sex Chromosomes focuses on the study of sex chromosomes, including human chromosomal abnormalities, behavior and characteristics of chromosomes, and cell division.
Mittwoch, Ursula
core
Specific loss of chromosomes 1, 2, 6, 10, 13, 17, and 21 in chromophobe renal cell carcinomas revealed by comparative genomic hybridization [PDF]
We analyzed 19 chromophobe renal cell carcinomas by means of comparative genomic hybridization. Two tumors revealed no numerical abnormalities. In the remaining 17 cases we found loss of entire chromosomes with underrepresentation of chromosome 1 ...
Speicher, Michael R. +7 more
core +1 more source
A presentation slide reflecting a microscopic view of Chromosomes, and labeled Life Science Flight Research Approach, Tissue culture and Cells ...
core
We present a novel and efficient non-integrating gene expression system in human embryonic stem cells (hESc) utilizing human artificial chromosomes (HAC), which behave as autonomous endogenous host chromosomes and segregate correctly during cell division.
Moralli, D. +36 more
core +1 more source
The complete sequence of the silkworm W chromosome uncovers its rapid evolution by large-scale duplications/deletions and translocation of W-linked genes. [PDF]
Li W +25 more
europepmc +1 more source
EasyCen: A Lightweight Framework for Centromere Localisation and Repeat-Organisation Profiling in Telomere-to-Telomere Genomes. [PDF]
Lv Y, Li Y, Li J, Mu X.
europepmc +1 more source
Identification of rare maternal copy number variants by genome-wide analysis of noninvasive prenatal screening data in 113,017 pregnant women. [PDF]
Hu L +7 more
europepmc +1 more source

