Results 101 to 110 of about 9,449,306 (346)
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Flow Sorting Enrichment and Nanopore Sequencing of Chromosome 1 From a Chinese Individual
Frontiers in Genetics, 2020 Sorting of individual chromosomes by Flow Cytometry (flow-sorting) is an enrichment method to potentially simplify genome assembly by isolating chromosomes from the context of the genome.
Lukas F. K. Kuderna +20 more
doaj +1 more source
A role for Separase in telomere protection [PDF]
, 2016 Drosophila telomeres are elongated by transposition of specialized retroelements rather than telomerase activity and are assembled independently of the sequence. Fly telomeres are protected by the terminin complex that localizes and functions exclusively
Bosso, Giuseppe +9 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
BMC Evolutionary Biology, 2012 Background Xenarthra (sloths, armadillos and anteaters) represent one of four currently recognized Eutherian mammal supraorders. Some phylogenomic studies point to the possibility of Xenarthra being at the base of the Eutherian tree, together or not with
Azevedo Nathália F +5 more
doaj +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Long-range autocorrelations of CpG islands in the human genome.
PLoS ONE, 2012 In this paper, we use a statistical estimator developed in astrophysics to study the distribution and organization of features of the human genome.
Benjamin Koester +4 more
doaj +1 more source
Normal human chromosomes have long G-rich telomeric overhangs at one end.
Genes & Development, 1997 Telomeres protect the ends of linear chromosomes from degradation and abnormal recombination events, and in vertebrates may be important in cellular senescence and cancer. However, very little is known about the structure of human telomeres.
W. Wright +4 more
semanticscholar +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
The Effect of Teratozoospermia on Sex Chromosomes in Human Embryos
The Application of Clinical Genetics, 2021 Dalia Mostafa Nayel,1 Hanan Salah El Din Mahrous,1 Emad El Din Khalifa,2 Soha Kholeif,1 Ghada Mohamed Elhady1 1Department of Human Genetics, Medical Research Institute, Alexandria University, Alexandria, Egypt; 2Department of Obstetrics and Gynecology ...
Mostafa Nayel D +4 more
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