Results 61 to 70 of about 164,419 (307)

Populations of doubled haploids for genetic mapping in hexaploid winter triticale. [PDF]

, 2018
To create a framework for genetic dissection of hexaploid triticale, six populations of doubled haploid (DH) lines were developed from pairwise hybrids of high-yielding winter triticale cultivars. The six populations comprise between 97 and 231 genotyped
Baenziger, PS, Lukaszewski, AJ, Metzger, RJ, Oleszczuk, S, Ponitka, A, Rabiza-Swider, J, Tyrka, M, Wedzony, M, Wos, H, Zimny, J, Ślusarkiewicz-Jarzina, A   +10 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Cytomolecular identification of individual wheat-wheat chromosome arm associations in wheat-rye hybrids [PDF]

, 2013
Chromosome pairing in the meiotic metaphase I of wheatrye hybrids has been characterized by sequential genomic and fluorescent in situ hybridization allowing not only the discrimination of wheat and rye chromosomes, but also the identification of the
Badaeva ED, Badaeva ED, Bass HW, Bedbrook J, Berkman PJ, Cifuentes M, Cifuentes M, Cifuentes M, Colas I, Conley EJ, Contento A, Cuadrado A, Devos KM, Devos KM, Fedak G, Fernandez-Kalvin B, Ferrer E, Fominaya A, Gale MD, Gerlach WL, Gill BS, Hernandez P, Huang S, I. Molnár, Jauhar PP, Kamstra SA, Le HT, Logojan A, Lukaszewski AJ, M. Megyeri, M. Molnár-Láng, Martinez-Perez E, Martinez-Perez E, Miller TE, Molnár I, Molnár I, Molnár I, Molnár I, Molnár-Láng M, Molnár-Láng M, Mukai Y, Munkvold JD, Nagaki K, Naranjo T, Naranjo T, Naranjo T, Prieto P, Qi L, Riley R, Riley R, Sabot F, Schwarzacher T, Sepsi A, Sharp PJ, Szakács, Sánchez-Morán E, Tischner T   +56 more
core   +1 more source

Visualization of chromosome condensation in plants with large chromosomes [PDF]

BMC Plant Biology, 2017
Most data concerning chromosome organization have been acquired from studies of a small number of model organisms, the majority of which are mammals. In plants with large genomes, the chromosomes are significantly larger than the animal chromosomes that have been studied to date, and it is possible that chromosome condensation in such plants was ...
Kuznetsova, Maria A., Chaban, Inna A., Sheval, Eugene V.   +2 more
openaire   +4 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Epigenetic consequences of interploidal hybridisation in synthetic and natural interspecific potato hybrids [PDF]

, 2019
Interploidal hybridisation can generate changes in plant chromosome numbers, which might exert effects additional to the expected due to genome merger per se (i.e., genetic, epigenetic and phenotypic novelties).Wild potatoes are suitable to address this ...
Camadro, Elsa Lucila, Cara, Nicolás, Ferrer, María Soledad, Marfil, Carlos Federico, Masuelli, Ricardo Williams   +4 more
core   +1 more source

Flow Sorting Plant Chromosomes

, 2016
Nuclear genomes of many important plant species are tremendously complicated to map and sequence. The ability to isolate single chromosomes, which represent small units of nuclear genome, is priceless in many areas of plant research including cytogenetics, genomics, and proteomics. Flow cytometry is the only technique which can provide large quantities
Vrána, J. (Jan), Cápal, P. (Petr), Čihalíková, J. (Jarmila), Kubaláková, M. (Marie), Doležel, J. (Jaroslav)   +4 more
openaire   +3 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

FISHIS: fluorescence in situ hybridization in suspension and chromosome flow sorting made easy. [PDF]

PLoS ONE, 2013
The large size and complex polyploid nature of many genomes has often hampered genomics development, as is the case for several plants of high agronomic value. Isolating single chromosomes or chromosome arms via flow sorting offers a clue to resolve such
Debora Giorgi, Anna Farina, Valentina Grosso, Andrea Gennaro, Carla Ceoloni, Sergio Lucretti   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source