Results 101 to 110 of about 1,419,260 (349)

UV micro-irradiation of the Chinese hamster cell nucleus and caffeine post-treatment immunocytochemical localization of DNA photolesions in cells with partial and generalized chromosome shattering [PDF]

, 1983
UV micro-irradiation of a small part of the Chinese hamster nucleus and caffeine post-incubation often results in shattered chromosomes at the first post-irradiation mitosis.
Cornelis, Cornelis, Cornelis, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Deaven, Fukuda, Gray, Hsu, Kihlman, Lehmann, Nilsson, Stack, Stubblefield, Taylor, Zorn, Zorn   +26 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Análise do cariótipo de Apuleia leiocarpa (Vog.) Macbr. Analysis of Apuleia leiocarpa (Vog.) Macbr. karyotype

Ciência Rural, 1999
Estudos citogenéticos da Apuleia leiocarpa foram realizados com o objetivo de determinar e montar o cariótipo da espécie. As sementes utilizadas foram coletadas na localidade de Cerrito, município de Santa Maria - RS.
Neiva Maria Frizon Auler, Alice Battistin   +1 more
doaj   +1 more source

Unscheduled DNA synthesis after partial UV irradiation of the cell nucleus [PDF]

, 1979
Cells of an euploid strain of the Chinese hamster synchronized in the G1 phase were microirradiated in the nucleus with a laser UV microbeam (λ = 257 nm) and pulse-labelled with [3H]thymidine. In autoradiographs of cells fixed immediately after the pulse
Berliner, Bostock, Brown, Christian Zorn, Christoph Cremer, Cleaver, Cohen, Comings, Cremer, Cremer, Cremer, Cremer, Deaven, Diaz, Dutrillaux, Ehmann, Feldman, Ghosh, Godin, Harris, Heneen, Hens, Hobarth, Hsu, Johnson, Juricek, Jürgen Zimmer, Loza Bonifaz, Moreno, Moreno, Nichols, Rasmussen, Robards, Sakharov, Sakharov, Schempp, Schwarzacher, Singh, Thomas Cremer, Vogel, Warburton, Werry, Wilkins, Williams, Yatani, Zorn, Zorn, Zorn   +47 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Detection of monosomy 7 in interphase cells of patients with myeloid disorders [PDF]

, 1990
Six patients, five with acute myeloid leukemia (AML) and one with a myelodysplastic syndrome (MDS), were found to have monosomy 7 by conventional cytogenetics at diagnosis.
Cremer, Thomas, Gezer, Sefer, Kolluri, Rukmini V., Manuelidis, L., Raza, Azra, Sait, Sheila   +5 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

(Ovo-)viviparity in the darkling beetle, Alegoria castelnaui (Tenebrioninae: Ulomini), from Guadeloupe

European Journal of Entomology, 2010
In the course of cytogenetic studies on Alegoria castelnaui Fleutiaux & Sallé 1889 (Coleoptera: Tenebrionidae: Tenebrioninae: Ulomini) from Guadeloupe, a number of adult specimens were dissected.
Anne Marie DUTRILLAUX, Dominique PLUOT-SIGWALT, Bernard DUTRILLAUX   +2 more
doaj   +1 more source

Biochemical evidence of chromosome homoeology among related plant genera. [PDF]

, 1975
Biochemical markers associated with homoelogous chromosome groups 3 and 7 of Triticum aestivum L. have been investigated in genetic stocks carrying chromosomes or chromosomal segments of the same homoeology groups from Agropyron elongatum and Secale ...
Aragoncillo, Aragoncillo, Barber, García-Olmedo, García-Olmedo, García-Olmedo, Gupta, Johnson, Johnson, Quinn, Redman, Riley, Rodríguez-Loperena, Rodríguez-Loperena, Sears, Sears, Sears, Shepherd, Torres   +18 more
core   +2 more sources

Three-Dimensional Maps of All Chromosomes in Human Male Fibroblast Nuclei and Prometaphase Rosettes

PLoS Biology, 2005
Studies of higher-order chromatin arrangements are an essential part of ongoing attempts to explore changes in epigenome structure and their functional implications during development and cell differentiation.
A. Bolzer, G. Kreth, Irina Solovei, D. Koehler, K. Saracoglu, Christine Fauth, S. Müller, Roland Eils, Christoph Cremer, M. R. Speicher, T. Cremer   +10 more
semanticscholar   +1 more source