Results 101 to 110 of about 1,536,776 (399)

Stretching the Rules: Monocentric Chromosomes with Multiple Centromere Domains [PDF]

, 2012
The centromere is a functional chromosome domain that is essential for faithful chromosome segregation during cell division and that can be reliably identified by the presence of the centromere-specific histone H3 variant CenH3.
A Kawabe, AE Hall, AF Dernburg, Alice Navrátilová, Andrea Koblížková, AW Higgins, BA Sullivan, BE Black, Beth A. Sullivan, DA Pepper, E Schroeder-Reiter, Elizabeth Schroeder-Reiter, Eva Chocholová, Gerhard Wanner, HR Lee, HS Malik, HS Malik, IC Moraes, J Macas, J Monen, Jiří Macas, JM Jiang, K Nagaki, K Nagaki, K Prufer, M Plohl, M Sanei, MD Bennett, OJ Marshall, P Binarova, P Neumann, P Neumann, P Neumann, P Novák, Pavel Neumann, PB Talbert, Petr Novák, PW Barlow, R ten Hoopen, RJ McFarlane, RK Dawe, S Heckmann, SA Ribeiro, T Haizel, Veronika Steinbauerová, W Zhang   +45 more
core   +4 more sources

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Aneusomy of chromosomes 7 and 17 predicts the recurrence of transitional cell carcinoma of the urinary bladder [PDF]

, 2000
Objective To determine if changes in chromosome 7 and 17 copy number can be used to predict recurrence in patients with primary noninvasive (pTa) or superficially invasive (pT1) transitional cell carcinoma (TCC) of the urinary bladder.
A.D. Watters, Bartlett, Bartlett, Cordon-cardo, Corless, Foresman, J.J. Going, J.M.S. Bartlett, K.M. Grigor, Kallioniemi, Knowles, McCredie, Murphy, Ozen, Povey, Pycha, Qureshi, S.A. Ballantyne, Sandberg, Saran, Sauter, Sauter, Sauter, Tolley, Underwood, Waldman, Yokogi   +26 more
core   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Cytogenetic analysis of five Hypostomus species (Siluriformes, Loricariidae)

Genetics and Molecular Biology, 2011
In this work, we analyzed the karyotypes of five species. Hypostomus cf. heraldoi, from the Mogi-Guaçu River, had 2n = 72 chromosomes, with a nucleolar organizer region (NOR) in one chromosomal pair.
Emanuel Ricardo Monteiro Martinez, Claudio Henrique Zawadzki, Fausto Foresti, Claudio Oliveira   +3 more
doaj  

Five new species of Pristimantis (Anura: Strabomantidae) from the coastal cloud forest of the Península de Paria, Venezuela

Journal of Threatened Taxa, 2015
Fieldwork in the cloud forest of Venezuela’s remote Península de Paria in 2001 resulted in the collection of several specimens that could unquestionably be classified as members of the genus Pristimantis.
Hinrich Kaiser, César L. Barrio-Amorós, Gilson A. Rivas, Claus Steinlein, Michael Schmid   +4 more
doaj   +1 more source

The degeneration of Y chromosomes.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2000
Y chromosomes are genetically degenerate, having lost most of the active genes that were present in their ancestors. The causes of this degeneration have attracted much attention from evolutionary theorists.
B. Charlesworth, D. Charlesworth
semanticscholar   +1 more source

Multicolour interphase cytogenetics: 24 chromosome probes, 6 colours, 4 layers [PDF]

, 2011
From the late 1980s onwards, the use of DNA probes to visualise sequences on individual chromosomes (fluorescent in-situ hybridisation - FISH) revolutionised the study of cytogenetics.
A.R. Thornhill, Abruzzo, Arnold, Camps, Celeda, Cremer, D. Ioannou, D.K. Griffin, Dauwerse, DeSilva, E.J. Meershoek, Egozcue, Emmerich, Ersfeld, Fiegler, Finch, Finch, Foster, Gabriel, Griffin, Griffin, Griffin, Griffin, Griffin, Handyside, Harper, Harper, Harton, Jauch, Julien, Kallioniemi, Kearns, Kolluri, Langer, Lichter, M. Ellis, Mann, Matsuzaki, Muller, Munne, Munne, Munne, Munne, Nederlof, Nordgren, Olszewska, O’Keefe, Pinkel, Quilter, Rennstam, Roberts, Rodriguez, Rottger, Sbracia, Schardin, Schrock, Speicher, Syvanen, Tempest, Tsuchiya, Walling, Wienberg   +61 more
core   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

UV micro-irradiation of the Chinese hamster cell nucleus and caffeine post-treatment immunocytochemical localization of DNA photolesions in cells with partial and generalized chromosome shattering [PDF]

, 1983
UV micro-irradiation of a small part of the Chinese hamster nucleus and caffeine post-incubation often results in shattered chromosomes at the first post-irradiation mitosis.
Cornelis, Cornelis, Cornelis, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Deaven, Fukuda, Gray, Hsu, Kihlman, Lehmann, Nilsson, Stack, Stubblefield, Taylor, Zorn, Zorn   +26 more
core   +1 more source