Results 11 to 20 of about 1,551,359 (398)
B Chromosomes – A Matter of Chromosome Drive [PDF]
B chromosomes are supernumerary chromosomes which are often preferentially inherited, deviating from usual Mendelian segregation. The balance between the so-called chromosome drive and the negative effects that the presence of Bs applies on the fitness ...
A. Houben
semanticscholar +4 more sources
Targeting chromosome trisomy for chromosome editing [PDF]
AbstractA trisomy is a type of aneuploidy characterised by an additional chromosome. The additional chromosome theoretically accepts any kind of changes since it is not necessary for cellular proliferation. This advantage led us to apply two chromosome manipulation methods to autosomal trisomy in chicken DT40 cells.
Kouji Hirota +3 more
openaire +4 more sources
Chromosomes, chromosome anomalies [PDF]
Educational Items on Chromosomes, chromosome anomalies.
Huret, JL, Leonard, C, Savage, JRK
openaire +3 more sources
Chromosome Painting of Mouse Chromosomes [PDF]
Chromosome painting enables the visualization of chromosomes and has been used extensively in cytogenetics. Chromosome paint probes, which consist of a pooled composite of DNA-FISH probes, bind to nonrepetitive sequences for individual chromosomes [1, 2].
Hua, Lisa L, Mikawa, Takashi
openaire +4 more sources
In RNA-mediated interference (RNAi), double-stranded RNAs (dsRNAs) target complementary mRNAs for degradation. New work demonstrates that essential chromosomal functions are mediated through RNAi protein components and short RNAs, which alter chromosome function at specific DNA loci via histone modification.
Abby F. Dernburg, Gary H. Karpen
openaire +2 more sources
Holocentric chromosomes possess multiple kinetochores along their length rather than the single centromere typical of other chromosomes [1]. They have been described for the first time in cytogenetic experiments dating from 1935 and, since this first observation, the term holocentric chromosome has referred to chromosomes that: i.
Mauro Mandrioli, Gian Carlo Manicardi
openaire +6 more sources
Architecture of metaphase chromosomes and chromosome scaffolds. [PDF]
We have developed procedures for depositing intact mitotic chromosomes and isolated residual scaffolds on electron microscope grids at controlled and reproducible levels of compaction. The chromosomes were isolated using a recently developed aqueous method. Our study has addressed two different aspects of chromosome structure.
Earnshaw, William C. +1 more
openaire +4 more sources
Hexavalents in spermatocytes of Robertsonian heterozygotes between Mus m. domesticus 2n 26 from the Vulcano and Lipari Islands (Aeolian Archipelago, Italy) [PDF]
The size and shape of the chromosomes, as well as the chromosomal domains that compose them, are determinants in the distribution and interaction between the bivalents within the nucleus of spermatocytes in prophase I of meiosis.
Eliana Ayarza +6 more
core +3 more sources
Factors Impacting Invader-Mediated Recognition of Double-Stranded DNA
The development of chemically modified oligonucleotides enabling robust, sequence-unrestricted recognition of complementary chromosomal DNA regions has been an aspirational goal for scientists for many decades.
Caroline P. Shepard +3 more
doaj +1 more source
A method for nucleic acid hybridization to isolated chromosomes in suspension [PDF]
A procedure was developed to provide differential fluorescent staining of metaphase chromosomes in suspension following nucleic acid hybridization. For this purpose metaphase chromosomes were isolated from a Chinese hamster x human hybrid cell line ...
Bier, Frank +5 more
core +1 more source

