Results 211 to 220 of about 1,573,429 (399)

Phase‐Separation of YAP Mediates AJUBA Super Enhancer Activation to Promote Aberrant Mitosis in Breast Cancer

Advanced Science, EarlyView.
YAP undergoes phase separation to activate the AJUBA super‐enhancer, driving aberrant mitosis through spindle checkpoint dysregulation in breast cancer. This study uncovers a mechanistic link between YAP condensates, super‐enhancer activation, and aneuploidy formation.
Rui Zhang, Qingwen Huang, Zhuo Chen, Weijian Meng, Hongliang Dong, Zhihong Qi, Liang Liu, Jie Shen, Daxing Xie   +8 more
wiley   +1 more source

An Achiasmatic Mechanism That Ensures the Regular Segregation of Sex Chromosomes in Male Meiosis in the Black Spongilla-fly <i>Sisyra nigra</i> (Retzius 1738), Sisyridae, Differs from the Mechanism Commonly Observed Within Neuroptera. [PDF]

Insects
Nokkala S, Nokkala C.
europepmc   +1 more source

Functional selection for the centromere DNA from yeast chromosome VIII [PDF]

, 1995
Ursula Fleig, J. Beinhauer, Johannes H. Hegemann   +2 more
openalex   +1 more source

VDLIN: A Deep Learning‐Based Platform for Methylcobalamin‐Inspired Immunomodulatory Compound Screening

Advanced Science, EarlyView.
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo, Yang Zhao, Xianle Rong, Chenxi Niu, Shiyu Hu, Qiang Liu, Fuping You   +6 more
wiley   +1 more source

B chromosome retrotransposed sequences persist through speciation, contributing to genomic and regulatory innovations in the fish genus Psalidodon (Characiformes, Acestrorhamphidae). [PDF]

PLoS One
Lasmar LF, Vidal MR, Nadai PCF, Dos Santos RZ, Machado RDC, Utsunomia R, Ruiz-Ruano FJ, Suh A, Oliveira C, M Z A Silva D, Foresti F.   +10 more
europepmc   +1 more source

Pulsed-Field Gel Electrophoresis Profile Changes Resulting from Spontaneous Chromosomal Deletions in Enterohemorrhagic Escherichia coli O157:H7 during Passage in Cattle

, 2009
Noriyo Yoshii, Yoshitoshi Ogura, Tetsuya Hayashi, Takashi Ajiro, Toshiya Sameshima, Muneo NAKAZAWA, Masahiro Kusumoto, Taketoshi Iwata, Masato Akiba   +8 more
openalex   +1 more source

NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction

Advanced Science, EarlyView.
NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu, Jing Luo, Li Yu, Daoxi Qi, Boyu Li, Yating Chen, Chen Wang, Xiaokang Zhang, Wenzheng Guo, Qiyong Lou, Gang Zhai, Yonglin Ruan, Jianfei Huang, Shengchi Shi, Zhan Yin, Fang Zheng   +15 more
wiley   +1 more source

Progress in Flax Genome Assembly from Nanopore Sequencing Data. [PDF]

Plants (Basel)
Pushkova EN, Arkhipov AA, Bolsheva NL, Rozhmina TA, Zhuchenko AA, Borkhert EV, Barsukov NM, Oleshnya GA, Milovanova AV, Moskalenko OD, Kostromskoy FD, Ivankina EA, Dvorianinova EM, Krupskaya DA, Melnikova NV, Dmitriev AA.   +15 more
europepmc   +1 more source

Centromere inactivation on a neo-Y fusion chromosome in threespine stickleback fish

, 2016
Jennifer N. Cech, Catherine L. Peichel
openalex   +1 more source

Translocation of a 190-kb mitochondrial fragment into rice chromosome 12 followed by the integration of four retrotransposons [PDF]

, 2005
Minoru Ueda, Nobuhiro Tsutsumi, Koh-ichi Kadowaki   +2 more
openalex   +1 more source