Results 41 to 50 of about 1,536,776 (399)
Genetic Diversity on the Sex Chromosomes
Genome Biology and Evolution, 2018 Levels and patterns of genetic diversity can provide insights into a population’s history. In species with sex chromosomes, differences between genomic regions with unique inheritance patterns can be used to distinguish between different sets of possible
Melissa A. Wilson Sayres
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Rapid generation of chromosome-specific alphoid DNA probes using the polymerase chain reaction [PDF]
, 1992 Non-isotopic in situ hybridization of chromosome-specific alphoid DNA probes has become a potent tool in the study of numerical aberrations of specific human chromosomes at all stages of the cell cycle. In this paper, we describe approaches for the rapid
A Gnirke +33 more
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Chromosome Structure: Coiling up chromosomes [PDF]
Current Biology, 1995 The mechanism by which eukaryotic chromosomes condense as cells enter mitosis has long been inaccessible to molecular biologists. An important clue has now been provided by a ubiquitous protein family, the SMCs.
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A dynamic mode of mitotic bookmarking by transcription factors. [PDF]
, 2016 During mitosis, transcription is shut off, chromatin condenses, and most transcription factors (TFs) are reported to be excluded from chromosomes. How do daughter cells re-establish the original transcription program? Recent discoveries that a select set
An, Luye +5 more
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The chromosomes of the Filariae [PDF]
Filaria Journal, 2005 An understanding of the nature of the chromosomes of the filariae is expected to greatly assist the future interpretation of genome data. Filarial development is not eutelic, and there does not seem to be a fixed number of cell divisions in the way that there is in Caenorhabditis.
Rory J. Post, Rory J. Post
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Genetics and Molecular Biology, 2006 We present the karyotypic characterization of 26 specimens of the side-necked turtle Hydromedusa tectifera collected in the upper Iguaçu River, Paraná state, Brazil.
Rafael Bueno Noleto +5 more
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Chromosome instability in Alzheimer’s disease [PDF]
Archives of Biological Sciences, 2011 Alzheimer’s disease (AD), as the most common form of dementia, has for many years attracted the attention of researchers around the world, primarily because of the problems of reliable diagnostic methods that could help in the early detection of this ...
Spremo-Potparević B. +3 more
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DNA methylation profiling of human chromosomes 6, 20 and 22
Nature Genetics, 2006 DNA methylation is the most stable type of epigenetic modification modulating the transcriptional plasticity of mammalian genomes. Using bisulfite DNA sequencing, we report high-resolution methylation profiles of human chromosomes 6, 20 and 22, providing
F. Eckhardt +26 more
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A fragmented metazoan organellar genome [PDF]
, 2008 Background: Animal mitochondrial (mt) genomes are characteristically circular molecules of ~16–20 kb. Medusozoa (Cnidaria excluding Anthozoa) are exceptional in that their mt genomes are linear and sometimes subdivided into two to presumably four ...
Erpenbeck, Dirk +2 more
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Chromosome cohesion: A polymerase for chromosome bridges [PDF]
Current Biology, 2000 How do cells ensure that sister chromatids produced during DNA replication stay connected with each other until their separation in anaphase? New insight is provided by the discovery of DNA polymerase kappa, which has been found to be required for building the connections between sister chromatids.
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