Chromosome instability in Alzheimer’s disease [PDF]
Archives of Biological Sciences, 2011 Alzheimer’s disease (AD), as the most common form of dementia, has for many years attracted the attention of researchers around the world, primarily because of the problems of reliable diagnostic methods that could help in the early detection of this ...
Spremo-Potparević B. +3 more
doaj +1 more source
Homologies in human and Macasa fuscata chromosomes revealed by in situ suppression hybridization with human chromosome specific DNA libraries [PDF]
, 1992 We established chromosomal homologies between all chromosomes of the human karyotype and that of an old world monkey (Macaca fuscata) by chromosomal in situ suppression (CISS) hybridization with human chromosome specific DNA libraries.
Cremer, Thomas +3 more
core +1 more source
Avian W and mammalian Y chromosomes convergently retained dosage-sensitive regulators
Nature Genetics, 2017 After birds diverged from mammals, different ancestral autosomes evolved into sex chromosomes in each lineage. In birds, females are ZW and males are ZZ, but in mammals females are XX and males are XY.
D. W. Bellott +15 more
semanticscholar +1 more source
Direct and indirect control of the initiation of meiotic recombination by DNA damage checkpoint mechanisms in budding yeast [PDF]
, 2013 Meiotic recombination plays an essential role in the proper segregation of chromosomes at meiosis I in many sexually reproducing organisms. Meiotic recombination is initiated by the scheduled formation of genome-wide DNA double-strand breaks (DSBs).
AJ MacQueen +40 more
core +3 more sources
Back to BAC: The Use of Infectious Clone Technologies for Viral Mutagenesis
Viruses, 2012 Bacterial artificial chromosome (BAC) vectors were first developed to facilitate the propagation and manipulation of large DNA fragments in molecular biology studies for uses such as genome sequencing projects and genetic disease models.
Robyn N. Hall +3 more
doaj +1 more source
A dynamic mode of mitotic bookmarking by transcription factors. [PDF]
, 2016 During mitosis, transcription is shut off, chromatin condenses, and most transcription factors (TFs) are reported to be excluded from chromosomes. How do daughter cells re-establish the original transcription program? Recent discoveries that a select set
An, Luye +5 more
core +1 more source
Genetic Diversity on the Sex Chromosomes
Genome Biology and Evolution, 2018 Levels and patterns of genetic diversity can provide insights into a population’s history. In species with sex chromosomes, differences between genomic regions with unique inheritance patterns can be used to distinguish between different sets of possible
Melissa A. Wilson Sayres
semanticscholar +1 more source
Immunocytochemical localization of chromatin regions UV-microirradiated in S phase or anaphase : Evidence for a territorial organization of chromosomes during cell cycle of cultured Chinese hamster cells [PDF]
, 1983 Chinese hamster cells (M3-1 line) in S phase were laser-UV-microirradiated (λ, 257 nm) at a small site of the nucleus. Cells were fixed either immediately thereafter or in subsequent stages of the cell cycle, including prophase and metaphase.
Avivi +33 more
core +1 more source
PLOS Genetics, 2020 Holocentric chromosomes possess multiple kinetochores along their length rather than the single centromere typical of other chromosomes [1]. They have been described for the first time in cytogenetic experiments dating from 1935 and, since this first observation, the term holocentric chromosome has referred to chromosomes that: i.
Mauro Mandrioli, Gian Carlo Manicardi
openaire +5 more sources
Genetic control of isozymes in the primary gene pool Phaseolus lunatus L. [PDF]
Biotechnologie, Agronomie, Société et Environnement, 1999 Suitable electrophoretic separation methods of 34 isozymes from 17 enzyme systems resolved in Phaseolus lunatus L. (Lima bean) were developed. Data from the migration of the staining zones indicated that three loci control EST, GPI, IDH and MDH ...
Maquet A. +3 more
doaj