Results 81 to 90 of about 1,530,143 (402)

Thermodynamic pathways to genome spatial organization in the cell nucleus [PDF]

, 2009
The architecture of the eukaryotic genome is characterized by a high degree of spatial organization. Chromosomes occupy preferred territories correlated to their state of activity and, yet, displace their genes to interact with remote sites in complex ...
Akhtar, Antonella Prisco, Bantignies, Berg, Binder, Binder, Bohn, Bon, Branco, Brown, Chuang, Cook, Cremer, de Laat, de Laat, Doi, Donohoe, Drissen, Fraser, Galande, Gerland, Hahnfeldt, Hancock, Hancock, Handwerger, Hediger, Jing, Kreth, Kurukuti, Kwon, Lanctôt, Lassig, Ling, Locke, Lomvardas, Maerkl, Marenduzzo, Marenduzzo, Mario Nicodemi, Massie, Maynard, Meaburn, Mergell, Misteli, Misteli, Morozov, Munkel, Munkel, Nicodemi, Nicodemi, Nicodemi, Nicodemi, Osborne, Osborne, Purbey, Sachs, Scialdone, Simonis, Spilianakis, Stanley, Takizawa, Vakoc, Xu, Yokota, Zhao   +64 more
core   +3 more sources

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

Chromosomes and phylogeny in Crepis, [PDF]

, 1930
P6 ...
Babcock, E. B. (Ernest Brown), 1877-1954, Hollingshead, Lillian, 1900-   +1 more
core   +2 more sources

Population growth of human Y chromosomes: a study of Y chromosome microsatellites.

Molecular biology and evolution, 1999
We use variation at a set of eight human Y chromosome microsatellite loci to investigate the demographic history of the Y chromosome. Instead of assuming a population of constant size, as in most of the previous work on the Y chromosome, we consider a ...
J. Pritchard, M. Seielstad, A. Pérez-Lezaun, M. Feldman   +3 more
semanticscholar   +1 more source

Chromosome Evolution: The Junction of Mammalian Chromosomes in the Formation of Mouse Chromosome 10 [PDF]

Genome Research, 2000
During evolution, chromosomes are rearranged and become fixed into new patterns in new species. The relatively conservative nature of this process supports predictions of the arrangement of ancestral mammalian chromosomes, but the basis for these rearrangements is unknown.
Eda Malaj, Mathew T. Pletcher, Bruce A. Roe, Ahn Do, Trang Do, Fang Chen, Roger H. Reeves   +6 more
openaire   +3 more sources

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Karyotype characterization of Malpighia emarginata (Malpighiaceae) Caracterização cariotípica de Malpighia emarginata (Malpighiaceae)

Revista Brasileira de Fruticultura, 2010
Malpighia emarginata Sessé & Mociño ex DC. or West Indian cherry (acerola) is a wild plant originated in southern Mexico, Central America and the northern region of South America.
Mateus Mondin, Carlos Alberto de Oliveira, Maria Lúcia Carneiro Vieira   +2 more
doaj  

Micro-Raman spectroscopy of chromosomes [PDF]

, 1984
Raman spectra of intact chromosomes (Chinese hamster), recorded with a microspectrometer, are reported. The spectra could be assigned to protein and DNA contributions.
Albrecht, Bradbury, Burki, de Mul, Erfurth, Ervin, Goodwin, Goodwin, Guillot, Klump, Koglin, Nordheim, Savoie, Séquaris, Thamann, Thomas, Wray   +16 more
core   +3 more sources

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source