Results 41 to 50 of about 1,793,188 (155)

A Prospective Observational Study on Chronic Anal Fissure in a Tertiary Care Centre

open access: yesNational Board of Examinations Journal of Medical Sciences
Background: Chronic anal fissure is a common and painful anorectal condition that may become resistant to conventional medical treatment in a significant proportion of patients.
M. Sadhana, M. Vimalnathan, B. Sridhar
doaj   +1 more source

A Case Series of Anal Carcinoma Misdiagnosed as Idiopathic Chronic Anal Fissure

open access: yes, 2016
Chronic anal fissure is a linear ulcer in the anal canal that has not cicatrized for more than 8-12 weeks of treatment. Most anal fissures are idiopathic and are located in the posterior midline.
Isabel Cotrim   +5 more
core   +1 more source

Topical Platelet Lysate Hydrogel in Patients With Anal Fissure [PDF]

open access: yesIranian Journal of Colorectal Research, 2014
Background Anal fissure is a painful tear or crack in the distal part of anal canal. It usually involves the epithelium, but in the long term it may extend to the whole anal mucosa.
Akram Jamshidzadeh   +8 more
doaj   +1 more source

Males are worse mothers: Comparing care patterns in a facultatively caring beetle

open access: yesInsect Science, EarlyView.
Why should biparental care exist if offspring fare just as well when only one parent is present? In the facultatively dependent burying beetle, Nicrophorus vespilloides, manipulating environmental quality reveals that biparental care benefits offspring in form of lower personal immune requirement and parents in term of weight gain.
Leon Müller   +2 more
wiley   +1 more source

CURRENT TREATMENT OF CHRONIC ANAL FISSURE.‎ [PDF]

open access: yesBasrah Journal of Surgery, 2004
This is a prospective study to test the hypothesis that topical isosorbide dinitrate (Isordil) is the best first ‎line of treatment of a chronic anal fissure.
Bahzad W Hamad, Faruk H Faraj
doaj   +1 more source

A Biweekly GLP‐1R Agonist Designed With Drug‐Free Intervals for Enhanced Efficacy, Receptor Homeostasis and Gastrointestinal Tolerability

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To develop a next‐generation, longer‐acting, more‐clinical‐benefits agonist to achieve sustained efficacy with improved tolerability. Methods CT130 was designed from semaglutide. Binding affinity was validated via molecular dynamics and cellular assays.
Wei Ding   +4 more
wiley   +1 more source

Anal Fissure: Is it becoming a medical disorder? Review Article

open access: yesمجله كليه طب الكندي, 2014
An anal fissure which does not heal with conservative measures as sits baths and laxatives is a chronic anal fissure. Physiologically, it is the high resting tone of the internal anal sphincter that chiefly interferes with the healing process of these ...
Ali Al-shaham,   +2 more
doaj  

Same‐night PrEP in community care: The Nightcafé model for male and transgender sex workers

open access: yesHIV Medicine, EarlyView.
Abstract Introduction Despite high risk of HIV infection, uptake of pre‐exposure prophylaxis (PrEP) remains limited among male and transgender sex workers (MSW and TSW), and data on tailored interventions to improve access are scarce. The Nightcafé programme addresses this gap by offering low‐threshold PrEP provision in a community‐centred setting ...
Elena Heizmann   +9 more
wiley   +1 more source

A clinical study on the management of chronic anal fissure [PDF]

open access: yes, 2021
Background: Fissure in ano is one of the most common benign anorectal disorder encountered in surgical practice causing considerable morbidity to the patient.This study is an attempt to clinical evaluation of chronic anal fissureand evaluation of ...
A. Vijaya Lakshmi   +2 more
core   +1 more source

European S2k guidelines for hidradenitis suppurativa/acne inversa Part 1. Epidemiology, diagnosis and clinical assessment

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Updated S2k hidradenitis suppurativa (HS) guidelines provide expert consensus on diagnosis, assessment and comorbidities. Expanded substantially since the 2015 version, they reflect rapid growth in HS literature and aim to improve generalist‐level patient care through evidence‐informed, consensus‐based guidance.
G. B. E. Jemec   +36 more
wiley   +1 more source

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