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Botulinum toxin preparations: areas for improvement and issues of standardisation
Scientific relevance. Botulinum toxin preparations are a good example of using a deadly toxin as a unique therapeutic agent. However, there are many unresolved issues related to biotechnology, biological activity, interchangeability, and standardisation ...
M. V. Savkina +4 more
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Immunogenicity of botulinum toxin [PDF]
Botulinum toxin treatment is the most common non-surgical cosmetic treatment. Although there are many available treatments using botulinum toxin, their effects are temporary and repeated injections are required. These frequent injections can trigger an immunological response. In addition, botulinum toxin acts as an antigen in the body; thus, its effect
Syeo Young Wee, Eun Soo Park
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Wide range applications of botulinum toxin in medicine - literature review
Introduction and purpose : Botulinum toxin is one of the most dangerous natural toxins. Botulinum toxin poisoning causes botulism. Botulism is a set of systemic symptoms resulting from flaccid muscle paralysis.
Aleksandra Serwik-Trandasir +9 more
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ObjectiveThe aim of this study was to detect botulinum toxin and Clostridium botulinum (C.botulinum) in 30 batches of infant formula milk powder obtained from an enterprise and to analyze the whole genome of the strain of C.
LUO Haipeng +8 more
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Botulinum toxin type A (Botox®) is thought to have antipruritic effects through inhibition of pruritic factors, including acetylcholine, substance P, and glutamate. The aim of this randomized, single-blind, placebo-controlled trial was to test the effect
Leigh A. Nattkemper +7 more
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Background and objective: The gold standard for the treatment of chronic anal fissure is lateral internal sphincterotomy. Botulinum toxin injection provides temporary alleviation of sphincter spasm and allows the fissure to heal.
Abdulqadir M. Zngana, Bawan Hiwa
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The Effects of Botulinum Toxin (BTXA) Dermal Injections on Facial Wrinkle Lines. [PDF]
Facial rejuvenation using Botulinum toxin A is one of the most popular aesthetic procedures. Many cosmetic applications of Botulinum toxin A are under evaluation.
Sung Chul Park +3 more
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To date, efficacy data on botulinum toxin type B (rimabotulinumtoxinB) in patients with cervical dystonia (CD) previously treated with botulinum toxin type A in a large population are lacking; thus, we aimed to evaluate type B efficacy in this patient ...
Ryuji Kaji +3 more
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Botulinum toxin type A in treatment of chronic migraine, spasticity and bruxism
Introduction: Nowadays, botulinum toxin has found use in many disease entities such as chronic migraine, spasticity, bruxism and many others. Among serotypes A-E, type A is mainly used in treatment.
Klaudia Kuliga +9 more
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Botulinum toxin, one of the most poisonous biological substances known, is a neurotoxin produced by the bacterium Clostridium botulinum. C. botulinum elaborates eight antigenically distinguishable exotoxins (A, B, C(1), C(2), D, E, F and G). All serotypes interfere with neural transmission by blocking the release of acetylcholine, the principal ...
Nigam P, Nigam Anjana
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