Results 51 to 60 of about 7,344,469 (193)

Chagas Heart Disease

, 2018
Chagas heart disease is becoming a worldwide health burden and represents a major cause of cardiovascular death in areas where it is endemic. Although rarely observed in Switzerland, increased awareness of the disease is important, particularly in times ...
Nisha Arenja, Jan Novak, Regula Fankhauser, Deborah Schild   +3 more
core   +1 more source

IL-1β is not critical to chronic heart dysfunction in mice with Chagas disease

Frontiers in Immunology, 2022
Long after Trypanosoma cruzi infection, 40% of individuals develop a progressive chronic chagasic cardiomyopathy (CCC), with systolic dysfunction and arrhythmias. Since we previously showed IL-1β mediates the development of systolic dysfunction and cardiac arrhythmias in diabetes mellitus and cardiorenal syndrome, and IL-1β remains elevated in Chagas ...
Camila Victória Sousa Oliveira, Oscar Moreno-Loaiza, Daniel Figueiredo-Vanzan, Isalira Peroba Ramos, Hilton Mata-Santos, Marcelo Torres Bozza, Claudia Neto Paiva, Emiliano Medei, Emiliano Medei, Emiliano Medei   +9 more
openaire   +3 more sources

Metagenomic detection and characterization of RNA viruses associated with Rhipicephalus linnaei (Audouin, 1826) ticks from the Amazon, Pará, Brazil

Medical and Veterinary Entomology, EarlyView.
Metagenomic analysis of Rhipicephalus linnaei from the Brazilian Amazon revealed the presence of RNA viruses belonging to the families Chuviridae, Phenuiviridae, Orthomyxoviridae and Rhabdoviridae. This study reports the first detection of Brown dog tick mivirus 1 and Brown dog tick phlebovirus 2 in Brazil, based on genomic characterization and ...
Lucas Henrique da Silva e Silva, Sandro Patroca da Silva, Fábio Silva da Silva, Leonardo Henrique Almeida Hernández, Daniel Damous Dias, Sâmia Luzia Sena da Silva, Lúcia Aline Moura Reis, Hanna Carolina Farias Reis, Bruna Laís Sena do Nascimento, Roberto Carlos Feitosa Brandão, Durval Bertram Rodrigues Vieira, Bruno Tardelli Diniz Nunes, Ana Cecília Ribeiro Cruz, Joaquim Pinto Nunes Neto   +13 more
wiley   +1 more source

Comparison of 1-year healthcare resource utilization and related costs for patients with heart failure in the Chagas and non-Chagas matched cohorts

Therapeutic Advances in Infectious Disease, 2022
Background: Chagas disease is one of the leading causes of heart failure (HF) in Latin Americans, and there are limited data available that examine related costs of care for patients with HF.
Mario J. Olivera, Adriana Arévalo, Lyda Muñoz, Sofía Duque, Juan Bedoya, Gabriel Parra-Henao   +5 more
doaj   +1 more source

Characteristics of the chronic Chagas disease patients and control individuals.

, 2015
CCD: chronic Chagas disease patients; NC: without heart involvement patients, CCC: chronic chagasic cardiopathy patients.*mixed population (white + mulatto + black) = 165 controls and 131 patientsCharacteristics of the chronic Chagas disease patients and
Camila de Freitas Oliveira (739714), Jeane Eliete Laguila Visentainer (585586), Divina Seila de Oliveira Marques (739715), Christiane Maria Ayo (739711), Ana Maria Sell (585587), Márcia Machado de Oliveira Dalalio (739713), Silvana Marques de Araújo (380686), Pâmela Guimarães Reis (739712)   +7 more
core   +1 more source

Virus‐specific alterations in placental structure and transporter expression following maternal arbovirus infection

The Journal of Physiology, EarlyView.
Abstract figure legend Arboviruses induce virus‐specific alterations in placental structure and functional markers. Chikungunya virus (CHIKV) exposure was associated with reduced syncytiotrophoblast and syncytial knot areas, increased cytotrophoblast proliferation (Ki‐67) and thyroid transporter (MCT8) expression, reduced protective (P‐gp and BCRP ...
Cherley B. V. Andrade, Enrrico Bloise, Natália L. Silva, Jair R. S. Braga, Sharton V. A. Coelho, Veronica M. O. Nascimento, Guinever E. Imperio, Camila O. S. Nunes, Antônio J. L. A. Cunha, Marcelo A. Pascoal‐Xavier, Luciana B. Arruda, Arnaldo Prata‐Barbosa, Kristin L. Connor, Tania M. Ortiga‐Carvalho   +13 more
wiley   +1 more source

Bradykinin B2 receptors of dendritic cells, acting as sensors of kinins proteolytically released by Trypanosoma cruzi, are critical for the development of protective type-1 responses [PDF]

, 2007
Although the concept that dendritic cells (DCs) recognize pathogens through the engagement of Toll-like receptors is widely accepted, we recently suggested that immature DCs might sense kinin-releasing strains of Trypanosoma cruzi through the triggering ...
Müller-Esterl Werner, Alessandra Granato, Schmitz Verônica, Scharfstein Julio, Tanowitz Herbert B, Scharfstein, Julio, Werner Müller-Esterl, Fnu Nagajyothi, de Arruda Luciana Barros, Nagajyothi, Fnu, Granato Alessandra, Pesquero João B, Müller-Esterl, Werner, Schmitz, Verônica, Luciana Barros de Arruda, Alexandre Morrot, Granato, Alessandra, Barros de Arruda, Luciana, Morrot Alexandre, Monteiro, Ana Carolina, Tanowitz, Herbert B., Julio Scharfstein, Nagajyothi Fnu, Morrot, Alexandre, Verônica Schmitz, João B Pesquero, Pesquero, João B., Monteiro Ana Carolina, Ana Carolina Monteiro, Herbert B Tanowitz   +29 more
core   +2 more sources

The potential influence of atherogenic dyslipidemia on the severity of chronic Chagas heart disease [PDF]

Revista da Associação Médica Brasileira, 2016
SUMMARY Introduction: chronic Chagas heart disease (CCHD) is the most common manifestation of American Trypanosomiasis, causing about 50,000 deaths annually. Several factors bear correlation with the severity of CCHD. However, to our knowledge, the assessment on the contribution of major cardiovascular risk factors (CRF), such as hypertension and ...
Peverengo, Luz, Rodeles, Luz, Vicco, Miguel Hernan, Marcipar, Iván   +3 more
openaire   +5 more sources

Illegal Gold Mining in the Brazilian Amazon: Environmental Degradation in Yanomami Indigenous Lands, and Regulatory Failures

Sustainable Development, Volume 34, Issue 7, Page 9232-9246, November 2026.
ABSTRACT Illegal gold mining has emerged as a major sustainability threat in the Amazon, eroding Indigenous rights, forest integrity, and climate mitigation efforts. This study examines how international market incentives relate to the expansion of illegal mining and associated deforestation within the Yanomami Indigenous Territory (YIT) from 2008 to ...
Shirléia Lago Santos, Ana Claudia de Araujo Moxotó, Jurandir Moura Dutra   +2 more
wiley   +1 more source

A Single Exercise Session Elicits a Transient Kynurenine Metabolic Signature in Health and Disease: A Systematic Review and Meta‐Analysis

The FASEB Journal, Volume 40, Issue 20, 31 October 2026.
A single exercise session transiently modulates systemic kynurenine pathway metabolism. Immediately after exercise, tryptophan decreases while kynurenine, KYN/TRP, kynurenic acid, and quinolinic acid increase. During recovery, lower tryptophan, higher KYN/TRP, and kynurenic acid remain.
Marcus Vinicius dos Santos Rangel, Gabriela Andrade Paz, Maria das Graças C. Souza, Marie Kupjetz, Tiffany Y. Wences Chirino, Philipp Zimmer, Paulo Farinatti, Juliana Pereira Borges   +7 more
wiley   +1 more source