Results 81 to 90 of about 92,292 (242)
Abstract Background Medullary thyroid cancer (MTC) standard of care includes multikinase inhibitors (MKIs), which can exacerbate disease‐related diarrhea, primarily because of non‐RET kinase inhibition. We report diarrhea and other patient‐reported outcomes (PROs) with selpercatinib, a highly selective RET inhibitor, among patients with RET‐mutant MTC ...
Lori J. Wirth +10 more
wiley +1 more source
Investigating the Quality of Sleep in Patients with Functional Constipation Referred to Shahid Mostafa Khomini Hospital in Ilam [PDF]
Background: Constipation is a very common disorder in adults. The aim of this study is to determine the relationship between sleep hours during the week and weekends with constipation in individuals.
Gholamreza Nouri +3 more
doaj
Abstract Objective In the dose‐escalation part of Study 101, which included multiple tumor types, objective responses were observed in 10 of 22 patients across multiple dose levels of farletuzumab ecteribulin (FZEC). We explored the safety/antitumor activity of FZEC in patients with platinum‐resistant ovarian cancer (PROC) from the Study 101 expansion ...
Kan Yonemori +11 more
wiley +1 more source
Obesity has become a global public health problem, and its relationship with gastrointestinal diseases has become a major concern. The visceral adiposity index (VAI) is a novel index to assess the distribution and content of visceral fat, and this study ...
Xiaoxian Yang +7 more
doaj +1 more source
Pelvic venous disorders in women: Diagnosis and management for gynecologists
Abstract Pelvic venous disorders (PeVD) are an underrecognized yet significant cause of chronic pelvic pain (CPP) in reproductive‐aged women, characterized by venous reflux, obstruction, or both. This clinical opinion provides a practical overview of PeVD for gynecologists, outlining its pathophysiology, common presentations, diagnostic approach, and ...
Tiffany Ni +5 more
wiley +1 more source
Background: Chronic functional constipation is a common problem that affects between 15-25% of the population and cause symptoms and disorders that creates discomfort, morbidity, and high costs for health care.
Taolin Agustinus +3 more
doaj
The trend of the aging population worldwide is becoming increasingly severe. As people age, constipation becomes increasingly common in older adults, causing varying degrees of physical and psychological harm to them.
Yiping Zhao +5 more
doaj +1 more source
Chronic constipation is a global medical, social, and economic problem due to its negative impact on patients’ quality of life and increased risk of colorectal cancer, cardiovascular and cerebrovascular disorders. The gut microbiota plays an important
Margarita Y. Serkova +2 more
doaj +1 more source
This study retrospectively analysed eight years of neonatal spinal ultrasound data from a major Australian children's hospital to assess the value of imaging for simple sacral dimples. Out of 448 scans, 195 were for an isolated simple dimple, and only two infants (1%) were found to have spinal dysraphism, both with other congenital anomalies.
Nyles Tattersall +5 more
wiley +1 more source
MODERN VIEWS ON A PROBLEM OF CONSTIPATION IN CHILDREN — A POSITION OF PEDIATRICIANS
This article highlights the issues of definition and classification of chronic constipation, the most prevailing pathology among gastrointestinal tract diseases.
F.Ch. Shakhtakhtinskaya
doaj +2 more sources

