Results 111 to 120 of about 5,096,258 (344)

Social determinants of breast cancer in the Caribbean: a systematic review

International Journal for Equity in Health, 2017
Background Breast cancer is the leading cause of cancer deaths among women in the Caribbean and accounts for >1 million disability adjusted life years. Little is known about the social inequalities of this disease in the Caribbean.
Catherine R. Brown, Ian R. Hambleton, Shawn M. Hercules, Miriam Alvarado, Nigel Unwin, Madhuvanti M. Murphy, E. Nigel Harris, Rainford Wilks, Marlene MacLeish, Louis Sullivan, Natasha Sobers-Grannum, The U.S. Caribbean Alliance for Health Disparities Research Group (USCAHDR)   +11 more
doaj   +1 more source

Mechanisms of ECG signs in chronic obstructive pulmonary disease [PDF]

, 2017
Marte Strømsnes Larssen, Kjetil Steine, Janne Mykland Hilde, Ingunn Skjørten, Christian Hodnesdal, Knut Liestøl, Knut Gjesdal   +6 more
openalex   +1 more source

Chronic kidney disease linked to SARS-CoV-2 infection: a case report [PDF]

, 2021
Georges Tarris, Alexis de Rougemont, Marie-Anaïs Estienney, J. Journet, Anne-Cécile Lariotte, Damien Aubignat, Jean-Michel Rebibou, Mathilde Funes de la Vega, Mathieu Legendre, Gaël Belliot, Laurent Martin   +10 more
openalex   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Effect of CD4 count on Mycobacterium tuberculosis infection rates in people living with HIV: a comparative study in prison and community

Scientific Reports
To evaluate the impact of the CD4 count on ESAT6-CFP10 (EC) skin test, QuantiFERON-TB Gold In-tube test (QFT) and tuberculin skin test (TST) in a large prison and communities in Jiangsu Province among people living with HIV (PLHIV).
Peng Lu, Yilin Lian, Zhongqi Li, Kai Wu, Zhuping Xu, Hao Xue, Jincheng Li, Xing Zhang, Rong Wang, Xiaoyan Ding, Jingjing Pan, Hui Ding, Qiao Liu, Limei Zhu, Haitao Yang   +14 more
doaj   +1 more source

Chronic wasting disease

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2007
Until recently, chronic wasting disease of cervids, the only prion disease affecting wildlife, was believed to be geographically concentrated to Colorado and Wyoming within the United States. However, increased surveillance has unveiled several additional pockets of CWD-infected deer and elk in 12 additional states and 2 Canadian provinces.
Sigurdson, C J, Aguzzi, A
openaire   +3 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Rehospitalization risk in community-dwelling schizophrenia patients receiving paliperidone palmitate: a retrospective cohort study in urban China

BMC Psychiatry
Background While long-acting injectable paliperidone palmitate (PP-LAI) improves treatment adherence in schizophrenia, rehospitalization risks persist under community management.
Cheng-Feng Liu, Jiao-Lian Yuan, Juan Cheng, Jing-Lu Lu, Wei-Yun Wang, Shao-Ling Zhong, Chu-Hong Lu, Li Qing, Ying Xu, Liang Zhou, Yan-Fang Guo   +10 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Prevalence and patterns of chronic disease multimorbidity and associated determinants in Canada

Health Promotion and Chronic Disease Prevention in Canada, 2015
Introduction: Multimorbidity is increasingly recognized as a key issue in the prevention and management of chronic diseases. We examined the prevalence and correlates of chronic disease multimorbidity in the general adult Canadian population in relation ...
K. C. Roberts, D. P. Rao, T. L. Bennett, L. Loukine, G. C. Jayaraman   +4 more
doaj   +1 more source